Actions of cortisol
Chapter 1
Chapter 6. Glucocorticoids, Thymus Function And Sex Hormone In Human Body Growing. Gordana Bjelakovic, Ivana Stojanovic, Tatjana Jevtovic-Stoimenov and Bojko Bjelakovic
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reas affected by too much cortisol the hippocampus, which plays a central role in learning and memory the prefrontal cortex, which regulates thoughts, emotions, and actions by “talking” to other brain regions
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5. Cortisol enhances _____ (in vessels) to help maintain blood pressure and also (increases or inhibits) the inflammation and immune response. 6. Besides cortisol, the adrenal cortex releases _____, which promotes salt and water retention, which …
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Cortisol is secreted by the zona fascilulata and is called a glucocorticoid because it affects glucose metabolism b. The actions of cortisol are to decrease protein synthesis, increase fatty acid release, and simulate glucose synthesis from noncarbohydrates.
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secretes glucocorticoids (cortisol) increase rate of protein catabolism & lipolysis. conversion of amino acids to glucose. stimulate lipolysis. provide resistance to stress by making nutrients available for ATP production. raise blood pressure by vasoconstriction. anti-inflammatory. The zona reticularis (inner zone) secretes androgens. insignificant in males
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Endocrine System: The Actions of Hormones on Target Cells. 1. The receptor is activated by the input signal that is the _____. This signal causes a biochemical change in the cell.
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General Considerations Of Cortisol Actions. Glucocorticoids promote the development of various organs and are necessary for the growth of many cell types. They were named for their glucose-regulating properties and have extensive influences on carbohydrate, lipid, protein and nucleic acid metabolism.
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Indeed, chronic cortisol elevations due to a failure to adequately regulate the HPA axis can eventually damage target tissues. However, cortisol is a life sustaining hormone and has many essential functions that allow coping and adaptation to stressors. For instance, cortisol plays a role in metabolism by increasing availability of energy stores.
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Cortisol also counteracts all these hormones and their actions in various ways. The apparent hypercortisolism of many adults (increased visceral fat, hypertension, insulin resistance, etc.) is not due to excessive cortisol levels but to the age-related declines in hormones that oppose cortisol’s actions.
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Cortisol is a glucocorticosteroid that is synthesized by the zona fasciculata of the adrenal cortex. Glucocorticosteroids enhance the action of hormones on body tissues and are essential in metabolic regulation during periods of injury and stress (Gerrard et al., 1985). Cortisol is regulated by the hypothalamic-pituitary-adrenal (HPA) axis.
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