Aldosterone antagonist contraindications
Aldosterone Antagonists in the Treatment of Heart Failure
Aldosterone antagonist Aldosterone antagonists are recommended in patients with HF or post-MI left ventricular dysfunction and LVEF ≤ 40% and moderate to severe symptoms, unless a contraindication to aldosterone antagonists is documented in the medical record Start at very low HF dosing.
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Nov 14, 2010 · A mineralocorticoid receptor antagonist should also be used with caution in patients with a higher baseline potassium (e.g., > 4.2mEq/L), elevated serum creatinine (e.g., > 1.6 mg/dl), or receiving ACEIs7, angiotensin II receptor antagonists, or other medications that may increase the risk for hyperkalemia (e.g., cyclosporine, tacrolimus ...
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Eplerenone is a relatively selective mineralocorticoid receptor antagonist with weak binding to androgen, glucocorticoid and progesterone receptors. Eplerenone prevents the binding of aldosterone, a key hormone in the renin-angiotensin-aldosterone-system (RAAS), which is involved in the regulation of blood pressure and the pathophysiology of ...
[DOC File]Aldosterone Antagonists (Eplerenone, Spironolactone) in ...
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Aldosterone antagonist . Aldosterone antagonists are recommended in patients with HF or post-MI left ventricular dysfunction and LVEF ≤ 40% and moderate to severe symptoms, unless a contraindication to aldosterone antagonists is documented in the medical record. Start at very low HF dosing.
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