Aldosterone antagonist drug list
[DOCX File]Australian public assessment for Eplerenone
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Drug action via a direct effect on a receptor. 1.2. Short-term and long-term effects of drugs at receptors. 1.3. ... For example, spironolactone is a competitive antagonist at aldosterone receptors in the distal convoluted tubule, and acetazolamide is an enzyme inhibitor, inhibiting the action of carbonic anhydrase in the proximal convoluted ...
[DOC File]Azilsartan National NME Drug Monograph
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Inspra (eplerenone) is a mineralocorticoid receptor antagonist with weak binding to androgen, glucocorticoid and progesterone receptors. It prevents the binding of aldosterone. Inspra has been considered previously by the Advisory Committee on Prescription Medicines (ACPM) on one occasion (238th (2005/1) meeting in 2005) prior to its initial ...
[DOCX File]Los Angeles Harbor College RN PRogram - LAHC
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Azilsartan is a selective AT1 subtype angiotensin II receptor antagonist. Effects mediated by the activation of AT1 receptors include vasoconstriction, production and release of aldosterone, sodium reabsorption by the kidney, and activation of the sympathetic nervous system. AT2 receptors function to oppose the effects of AT1 receptors.
Aldosterone Antagonists in the Treatment of Heart Failure
Eplerenone is a selective mineralocorticoid receptor antagonist. Aldosterone, the receptor’s predominant endogenous ligand, is involved in the pathophysiology of heart failure (HF) via its effects causing sodium retention, magnesium and potassium loss, sympathetic activation, parasympathetic inhibition, myocardial and vascular fibrosis, and ...
[DOCX File]Attachment 2. Extract from the Clinical Evaluation Report ...
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Aldosterone Antagonist. This type of medicine blocks the effects of the hormone aldosterone. Aldosterone can cause the heart muscle to get bigger and stiffer. This may decrease how well your heart pumps. Aldosterone also causes your body to retain sodium (salt) and water, and that may make you bloated and congested.
[DOCX File]3.Antidepressants - Michigan State University
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Potassium-sparing diuretic, aldosterone antagonist - Spironolactone (Aldactone) 100mg po twice daily. Albumin 5% in 500mL to run over 30 minutes. Normal Saline 0.9% - NaCl 100mL IV continous rate . Potassium Chloride (KCl) 20mEq IVPB x 1 over 1 hour. Sodium Bicarbonate 50mEq IVP x 1
[DOCX File]SEDA-19
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anti-arrhythmic drug. Some risk of proarrhythmia (less than other Na+ blockers). Minimal effect on ECG. Parenteral use only. Losartan Competitive . angiotensin II (AT1) receptor antagonist; inhibits vasoconstriction, aldosterone release and hypertrophic growth. 1st line treatment of . CHF. and . HTN. Fewer side effects than ACE inhibitors ...
[DOC File]Cardiovascular Drugs for Pharmacology Final
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This list is based upon the 2009 NPLEX drug list, which may have been updated. Ignore numbers on left hand side. CARDIOVASCULAR. ... Spironolactone → aldosterone antagonist, K+ sparring diruetic. 24 hyperkalemia and HORMONAL affects (breast deformity and tenderness.
Patient assessment
(Solian) - Selective dopamine antagonist. Asenapine (Saphris) is a 5-HT2A- and D2-receptor antagonist under development for the treatment of schizophrenia and acute mania associated with bipolar disorder. ... 7.Antihypertensive drug ... Aldosterone antagonists. Aldosterone. receptor antagonists: eplerenone. spironolactone. Aldosterone ...
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