Alternatives to proton pump inhibitors
[DOC File]Photodynamic Therapy and High Grade Dysplasia in Barrett’s ...
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Treatment with proton pump inhibitors (PPIs) is effective in relieving symptoms and healing esophagitis however long-term treatment with PPIs as well as antireflux surgery has failed to regress BE [11,12]. Therefore, prevention of dysplastic changes by control of gastroesophageal reflux is unlikely [13].
[DOCX File]Background - SPS
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The PACA (Proton Pump Inhibitors and Clopidogrel Association) Prospective Randomised Study. Journal of the American College of Cardiology 2009; 54: 1149-1153. Sibbing D, Morath T, et al. Impact of proton pump inhibitors on the antiplatelet effects of clopdiogrel.
[DOCX File]Lippincott Williams & Wilkins
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Proton-pump inhibitors. Risk of . C. lostridium. ... or antiplatelet agents; use of proton-pump inhibitor or misoprostol reduces but does not eliminate risk. Upper gastrointestinal ulcers, gross bleeding, or perforation caused by NSAIDs occur in approximately 1% of patients treated for 3–6 months and in ~2%–4% of patients treated for 1 year ...
[DOC File]Pharmacy Benefits Management Services Home
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No adjustment needed for atorvastatin Proton pump inhibitors No significant effects on antiplatelet activity of ticagrelor Can be co-administered Ethinyl estradiol/levonorgestrel Ethinyl estradiol: 31% and 20% increase in Cmax and AUC; not considered clinically significant. Levonorgestrel: no changes
[DOC File]1: Gastro-intestinal system
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Proton pump inhibitors should be used with caution in the elderly. There may be an association between PPI use & Clostridium difficile infection and osteoporosis. Careful consideration should be made to the risk benefit ratio. MHRA Drug Safety Update. Proton pump inhibitors in long-term use: Reports of hypomagnesaemia. Article date: April 2012 ...
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