Ampicillin coverage spectrum
[DOCX File]SOHM LIBRARY - SOHM Library
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coverage with ampicillin or penicillin G for children hospitalized with uncomplicated CAP. ... Narrow-spectrum therapy was not inferior to broad-spectrum antibiotics in all measured outcomes including LOS, duration of oxygen, duration of fever, or readmission rates within 7 days. Describe Strategy. Interactive, analogies, visuals.
[DOCX File]Neurosurgery
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need broad spectrum coverage: gram +, gram -, possibly pseudomonas and MRSA. Cefepime + vancomycin, Piperacillin/Tazo + vanc, Meropenem + vanc. MDR PNA: patients with a h/o resistant organisms, current hospitalization >5 days, significant drug resistance in unit/community. Broad coverage as above in HCAP + addition of FQ, aminoglycoside or ...
[DOC File]Drug - University of Washington
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The sulbactam improves the S. aureus and anaerobic coverage of ampicillin, but only modestly improves G- coverage DOC for which diseases Intra-abdominal infections With advanced macrolide (azithromycin) for CAP treated on inpatient basis, non ICU (especially if aspiration pneumonia is a concern)
[DOC File]General Outline for Antibiotics (a good study guide)
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c) beta-lactamase inhibitors (clavulanate, sulbactam) extend the spectrum somewhat. 2. absorption. a) both are acid resistant but more amoxicillin is absorbed by the intestinal tract than ampicillin after an oral dosage . b) food interferes with absorption of ampicillin …
[DOCX File]Clinical advice concerning the shortage of benzylpenicillin
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For most clinical indications, ampicillin or amoxicillin injections can be safely substituted for benzylpenicillin. The general recommended dosage equivalence is: Adult :1.2g benzylpenicillin = 1g ampicillin or 1g amoxicillin injection. Children: 60mg/kg benzylpenicillin = 50mg/kg ampicillin or 50mg/kg amoxicillin injection
[DOC File]Frank Lowy - Columbia University
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limited spectrum . bactericidal . Gram-positive cocci – staphylococci, streptococci, and enterococci (only E. faecium not E. faecalis) Only parenteral. well-distributed. metabolized by liver to inactive metabolites. primarily used when have vancomycin-resistant enterococcus – 3rd line drug of choice for enterococcus after ampicillin and ...
[DOCX File]Supplementary table 1 - Clinical Microbiology and Infection
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Remark: if the treating team initiates empiric antimicrobials, they should assess for de-escalation daily, and re-evaluate the duration of therapy and spectrum of coverage based on the microbiology results and the patient’s clinical status
[DOC File]Pharmacology Paper Chase - Tripod
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Amoxicillin, ampicillin, bacampicillin. Extended spectrum: azlocillin, mezlocillin, carbenicillin, piperacillin, ticarcillin (anti Pseudomonas) Lots of drugs didn’t work for Pseudomonas. Aminoglycosides (AG) did work but had to be given IV and were toxic, so needed to discover new drugs for Pseudomonas. Orally given drugs. Pen V. Oxacillin in ...
[DOC File]Lecture 7 - Harper College
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Aminopenicillins (Broad Spectrum) Amoxicillin (Amoxil), Ampicillin (Omnipen), Bacampicillin HCL (Spectrobid) - Gram + & Gram - - Costlier - Inactivated by beta-lactamases = ineffective against Staphylococcus aureus (staph. A) - Amoxicillin = most prescribed PCN derivative for adults & children.
[DOC File]CHOICE OF THE PROPER ANTIMICROBIAL AGENT
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Examples of combination therapy with broad-spectrum coverage. Cephalosporin + aminoglycoside or fluoroquinolone. Decreased Toxicity . Reduce the amount of drug required for treatment and, thus, to reduce dose-related toxicity. Synergism . Penicillin enhances the uptake of aminoglycosides by enterococci ( synergistic killing of the organisms.
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