Atorvastatin long term side effects
[DOC File]Drug/Application
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Variable effects on . thyroid function. because it is iodinated; some pulmonary toxicity. ↑levels of warfarin and digoxin with amiodarone – often used in same patients! Short-term i.v., or long-term oral treatment. Prolongs Q-T interval. Good for pts. w/ CHF or post-infarct.
[DOCX File]Attachment 1. Product Information for Atozet/Zeteze
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There were 4 deaths in the short term studies; 2 in the ezetimibe + atorvastatin group and one further death in a long term study. None was considered treatment related. The exposure adjusted SAE rate (per 100 patient years) in the short term studies (12.3) was mildly higher than atorvastatin (9.6).
[DOCX File]Statins: - Students Today, Pharmacists Tomorrow | IPSF
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Moreover, Statin-induced myopathy is caused by the long-term use of higher doses, when certain drugs have been used previously (cyclosporine, erythromycin and clarithromycin), we should be fully aware of toxic side effects and other drug interactions and monitor for adverse reactions.
Atorvastatin (Lipitor) Side Effects & Complications | The People's P…
Use caution when driving or performing other dangerous tasks until drug effects are known. Report any adverse effects to a health care provider immediately: severe stomach pains nausea & vomiting, fever chills sore throat, diarrhea, or muscle cramping Monitor triglyceride and cholesterol levels during therapy (to evaluate effectiveness of drug therapy).
[DOC File]PROTOTYPE DRUG: Atorvastatin (Lipitor)
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Long term studies, P2154). Eight percent of subjects discontinued treatment early, 5% were due to adverse events. There was no trend across treatment groups in the distribution of subjects who discontinued or in the reasons for discontinuation. Patients receiving all doses of ATOZET were compared to those receiving all doses of atorvastatin.
[DOCX File]Heather n Folz, pharmD
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The Scandinavian Simvastatin Survival Study was the first clinical trial to demonstrate conclusively that long-term therapy with statins substantially reduced the risk of death from all causes, as well as from cardiac events, in middle-aged patients with coronary heart disease and raised cholesterol.
[DOC File]Cardiovascular Drugs for Pharmacology Final
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Less often, HIV drugs can cause serious or long-term side effects. These effects depend on the type of HIV drugs used. A healthcare provider can offer more information. To have information on the side effects of each antiretroviral drug, ... atorvastatin, fluvastatin, and pravastatin.
[DOC File]FACTS ABOUT STATINS
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Clearance varies among and within individuals - cleared by cytochrome p450 in liver Common side effects- nausea, tremor, HA, agitation, and insomnia Severe toxicity > 30 mcg -Seizures, arrhythmias Conditions that decreased elimination:
[DOCX File]Australian public assessment report for Ezetimibe ...
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Atorvastatin (Lipitor) safe for the most part. Some people have stomach upset, gas, heartburn, or diarrhea with their statin. Take it with supper if you have these symptoms and tell your prescriber if these side effects are severe or don’t go away. A more serious but not common side effect is muscles soreness. Can be a sign of muscle injury.
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