Bactrim ds dosing for cellulitis

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      • Bactrim would be an alternative drug • I always add Bactrim DS for proven MRSA pneumonia. I will not use linezolid until there is a prospective comparison with TMP-SMZ. Clinical presentation • All children had empyema and rapidly progressing pneumonia. This is a terrible disease.

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      Treatment: high-dose steroids (up to ~100 mg/day IV then PO) / improvement should occur with first few weeks with continued improvement over 3 to 6 months / continue initial dose until strength and CK normalizes for 4-8 weeks / CK can remain elevated due to leaky membranes and strength can remain low with normal CK due to steroid myopathy (i.e. steroid myopathy does not cause elevated CK) / …

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      Renal dosing: CrCl 10-50: 75% of the dose CrCl

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