Base pair substitution
[DOC File]DNA Mutations during Protein Synthesis – Notes
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Point mutations can affect protein structure and function (pp. 322-325, FIGURE 17.24) Point mutations are changes in one base pair of DNA. Base-pair substitutions can cause missense or nonsense mutations, which are often detrimental to protein function. Base-pair insertions or deletions may produce frameshift mutations that disrupt the mRNA ...
[DOC File]AP Biology - Weebly
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Base Pair Substitution. In a base pair substitution, only a single base pair is affected. For example, a single G-C pair might be replaced by an A-T pair. If the change is in the third position of the codon, it might not alter the genetic message at all. However, it may change the code and call for a completely different amino acid.
[DOC File]Section Notes 3 - Harvard University
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Substitution is the replacement of one base pair with another. It is the cause of missense and nonsense mutations. Deletion: a mutation that happens when base pairs are removed from the genetic code.
[DOCX File]Chapter 09 - From DNA to Protein
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A scoring matrix is a table of values that describe the probability of a residue (amino acid or base) pair occurring in an alignment of related sequences. Not all substitutions are created equal: Mutations tend to favor a given set of substitutions
[DOC File]Home - Hillsboro City Schools
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substitution of one amino acid for another. ... So the probability, P, that a base pair is both mutated and lies within the coding region = P (base pair is mutated) * P (base pair is in coding region) = (175/6.5 billion) * (0.03) = 7.7 x 10-8. Therefore, there is a 1 in 1/(7.7 x 10-8
What is base pair substitution?
A base-pair substitution changes only one amino acid. By contrast, base insertions and deletions can change many amino acids in a peptide chain by shifting the entire sequence of codons. A base insertion . is the addition of one or more bases into a nucleotide sequence. Consider two …
[DOC File]Biology 30 - Patricia Schwandt Courses
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Point mutations can affect protein structure and function (pp. 322-325, FIGURE 17.24) Point mutations are changes in one base pair of DNA. Base-pair substitutions can cause missense or nonsense mutations, which are often detrimental to protein function. Base-pair insertions or deletions may produce frameshift mutations that disrupt the mRNA ...
[DOC File]Chapter 17
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Substitution – one base-pair is replaced by another. 2. Insertion – one or more base pairs is added to a sequence. 3. Deletion – one or more base pairs is lost from a sequence . There are four possible results of a mutation. 1. Silent mutation: When a base pair is substituted but the change still codes for the same amino acid in the sequence.
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