Benzodiazepine equivalent doses
[DOC File]Patients not appropriate for offering benzodiazepine ...
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Convert patient to equivalent daily dose of diazepam preferably taken at night. Diazepam is a long acting benzodiazepine and makes the dose reduction much easier. It does not produce the “kick” often experienced after larger doses of temazepam, but its calming effect may last up to 24 hours.
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For people withdrawing from these potent, short-acting drugs it has been advised that they switch to an equivalent dose of a benzodiazepine with a long half life such as diazepam (5). Diazepam is available as 2mg tablets which can be halved to give 1mg doses. This means the dose can be reduced in stages of 1mg every 1-4 weeks or more.
[DOC File]Basic Facts about Benzodiazepines
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Her work in the field of benzodiazepine withdrawal syndrome resulted in what has become known as the Ashton Manual. Dr. Ashton recommends changing faster-acting benzos like Xanax, Ativan and Klonopin for an equivalent dose of Valium, using the Valium to get a smoother, more controlled taper. This is all explained in her manual.
[DOC File]ALCOHOL WITHDRAWAL: PATHPHYSIOLOGY, DIAGNOSIS AND TREATMENT
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Symptom-triggered vsfixed-schedule doses of benzodiazepine for alcohol withdrawal: a randomizedtreatment trial. Arch Intern Med 162: 1117-1121, 2002. 32. Myrick H, Brady KT, Malcolm R.Divalproex in the treatment of alcohol withdrawal. Am J Drug Alcohol Abuse 26: 155-160,2000. Appendix 1.
[DOCX File]Model opioid prescribing policy - UW Departments Web Server
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Benzodiazepines, barbiturates, sedatives, carisoprodol, non-benzodiazepine hypnotics This section discusses guideline-consistent care processes for patients with pain lasting between 0 and 12 weeks. Encourage the use of evidence-based non-opioid and non-pharmacological modalities for acute and subacute pain whenever reasonable and clinically ...
How to recognise and treat benzodiazepine dependence
Initial doses should be according to the patient's current tolerance. In those requiring high doses (over 30mg diazepam daily or equivalent), this may be confirmed by an examination 3 hours after witnessed dosing. Reductions should be no more than 25% of the daily dose at 2 week intervals.
[DOCX File]Revised submission as of 7-20-14 for ASP.docx.docx
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Title: An Informal Review of Opioid Dependence (Addiction) Associated with Chronic Opioid Assisted Therapy (COAT) for Chronic Pain. Author: James K. Rotchford, M.D., M.P.H.
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Some anesthesiologists utilize benzodiazepine-sparing techniques due to the evidence in the ICU population relating benzodiazepine use to delirium, 1,2,5,7,8 but some anesthesiologists specifically administer benzodiazepines for their amnestic properties due to a higher than average rate of intraoperative awareness in the cardiac surgery ...
[DOC File]addictions.richard_matthews.fastmail.fm
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Equivalent doses can be calculated if the actual doses are known before beginning the tapering process (Table 4). A long-acting benzodiazepine is more effective than short-acting preparations in suppressing withdrawal symptoms and in producing a gradual and smooth transition to the abstinent state.
[DOCX File]Doctor 2015 - Lejan JU
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Transdermal patch: long-acting form, 12 hours for onset, 48-72 hours half-life. 12 micrograms or 25 micrograms/ hour, 25 microgram fentanyl is equivalent to 50-60 mg of oral morphine in 24 hours, in other words, the fentanyl transdermal patch is equivalent to a high-dose morphine regimen.
[DOC File]Prepared By
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The Emit® II Plus Benzodiazepine Assay detects benzodiazepines and benzodiazepine metabolites in human urine. The following table lists the concentrations of compounds that produce a result that is approximately equivalent to the Emit® Calibrator/Control Level 3; 200 ng/mL and Level 4; 300 ng/mL calibrator/control cutoffs, respectively.
[DOC File]Benzodiazepine Detoxification during Opiate Replacement ...
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There is no evidence to determine the best clinical practice regarding benzodiazepine detoxification during opiate replacement treatment. 5 Existing practice in Grampian. Guidelines exist in Grampian for benzodiazepine withdrawal (not specifically with opiate treatment) (Eagles et al 2006). These recommend reducing doses by 10-20% every fortnight.
[DOC File]Magellan Rx Management
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All solid oral dosage forms of benzodiazepine agents: Effective December 7, 2010 ... Options include titrating doses downward, adjusting strengths and quantities, or decreasing the number of benzodiazepine agents prescribed. ... 100 25 mg Drug Common Brand Names Elimination Half Life in hoursa b Approximate Equivalent Oral Dosagesc Clonazepam ...
[DOC File]G e n e r a l P r a c t i t i o n e r H a n d b o o k - NCETA
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In patients who have previously had severe withdrawal, it may be necessary to substitute a long-acting benzodiazepine such as diazepam. The following table gives approximate equivalent doses of diazepam. Note that due to differences in metabolism the exact equivalent will vary from patient to patient.
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