Benzyl alcohol toxicity
[DOC File]GUIDELINE FOR GOOD CLINICAL PRACTICE
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The formulated product, GF-3301 Herbicide, containing 300 g/L florpyrauxifen-benzyl, has low acute oral toxicity (LD 50 >5000 mg/kg), dermal toxicity (LD 50 >5000 mg/kg) and inhalational toxicity in rats (LC 50 >5660 mg/m3). It was not a skin irritant in rabbits but was a slight eye irritant in rabbits.
[DOCX File]Form for submission of comments - EFPIA
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Benzyl Alcohol (preservative) Benzyl alcohol toxicity may lead to prolonged recovery and hyperkinesia in cats, and neurological signs such as tremors in dogs and fatalities in both species. There is no specific antidote; supportive treatment should be given.
[DOCX File]www.arcorepoxy.com
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150mg benzyl alcohol, 3250mg macrogol 300, 1210mg absolute ethyl alcohol, citric acid and polysorbate 80 Product diluted with preservative-free saline to a concentration of 0.1mg/mL and administered via an Ommaya or Rickham Reservoir.
[DOC File]Pharmacy Benefits Management Services Home
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The toxicity of benzyl alcohol has been studied extensively, including acute, short-term and long-term toxicity, carcinogenicity, genotoxicity and developmental toxicity. In juvenile rats with a mature metabolic system (PND22, equivalent to a 2-year old child) it was shown that benzyl alcohol dosed up to 6 weeks (until PND64) has a similar ...
[DOCX File]Veterinary Medicines Directorate
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The toxicity of some excipients may vary across pediatric age groups and between pediatric and adult populations, e.g., benzyl alcohol is toxic in the preterm newborn. Depending on the active substance and excipients, appropriate use of the medicinal product in the newborn may require a new formulation or appropriate information about dilution ...
[DOCX File]Public Release Summary on the evaluation of the new active ...
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The AIHA recommended WEEL (workplace environmental exposure level) for Benzyl alcohol is 8.1.2 Recommended monitoring procedures If this product contains ingredients with exposure limits, personal, workplace atmosphere or
Benzyl Alcohol: Toxic Agent in Neonatal Units
Benzyl alcohol toxicity: Spinosad topical suspension contains benzyl alcohol and is not recommended for use in neonates and infants under the age of 6 months. Systemic exposure to benzyl alcohol has been associated with serious adverse reactions, including “gasping syndrome,” and death in neonates and low birth weight infants.3
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