Causes of elevated inr
[DOC File]Anticoagulation - Clinical Protocol
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The physician will seek or verify underlying causes of conditions requiring anticoagulation (for example, hyperthyroidism or mitral stenosis related to atrial fibrillation), and identify potentially reversible causes. ... In individuals receiving warfarin who are bleeding or who have a markedly elevated PT/INR, it may suffice to stop the ...
PT, PTT, FIB, INR by ACL 7000
4.3. The INR for a normal patient is 0.9 to 1.1. For non-medicated patients, INR values greater (>) than 1.5 are critical. 4.4. For standard oral anticoagulant therapy, the recommended therapeutic range for the INR is 2.0 to 3.0. 4.5. For high-dose oral anticoagulant therapy, the recommended therapeutic range the INR is 2.5 to 3.5.
[DOC File]Harvard Vanguard Medical Associates
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DVT/PE while at therapeutic level of anticoagulation, without identifiable cause or with identifiable cause likely to persist 2.5-3.5, or as indicated by INR at time of event 3.0, or as indicated by INR at time of event Lifetime; consider filter when at high risk for life-threatening PE, when higher level of anticoagulation is precluded, and/or ...
[DOC File]Coagulopathy - Stanford University
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Causes platelet dysfunction. Bleeding time may increase 3 to 4 fold. May be reversible with DDAVP or cryoprecipitate. Liver failure. In complete failure, patients may require 2 units of FFP every 2 hours to maintain adequate hemostasis. Preoperative Drug Therapy: Warfarin. Factor 7 is the first factor depleted, which is why the PT is affected ...
[DOC File]EmergencyPedia – Free Open Access Medical Education
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INR elevated with normal d-dimer - ?Snakebite (Blacksnake) Vertigo. Normal Lung USS – use of M mode. ... Sudden onset headache - strange worded about causes and history, 4 x parenteral tx with pro and con. 23) Urine paeds - interpret, cell counts for types of catch, admin q.
[DOC File]Pharmacology and Management of the Vitamin K Antagonists*
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Because the absolute daily risk of bleeding is low even when the INR is excessively prolonged, many physicians manage patients with minimally elevated INRs by more frequent monitoring without a dose change220 or for higher INR values between 4.0 and 10.0, by stopping warfarin for 1 day or more, reducing the weekly dose, and monitoring more ...
[DOC File]ISMP Medication Safety Alert
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The patient took double the dose of warfarin daily for several days before presenting to a clinic with an elevated INR. Most pharmacy systems are not implemented in such a way to receive discontinued e-Rx.
[DOC File]Jaundice or elevated bilirubin - Pennine VTS
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Routine USS if INR normal and not jaundiced or malignancy not suspected. Urgent USS/referral if INR prolonged, low albumin or patient jaundiced . 2ww if malignancy suspected Appendix. Drugs which causes abnormal LFTs. Common drug causes of raised …
[DOC File]CV-Med5566
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causes elevated INRs because of test interference, making the transition to warfarin difficult. Adverse Effects. HEMORRHAGE: dose related; increased in patients with renal insufficiency, liver injury, or recent trauma and/or treatment with other anticoagulants. DRUGS THAT INHIBIT SYNTHESIS OF COAGULATION FACTOR PRECURSORS: 4-HYDROXYCOUMARIN ...
[DOC File]Gastroenterology - Stanford University
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Non-pancreatic causes of elevation are renal failure, viscus perforation/infarct, ectopic pregnancy, cancer, macroamylassemia. Serum lipase: more sensitive and specific and remains elevated longer than amylase. Serum calcium, lipids, LDH, CBC, albumin, glucose, liver chemistries. RUQ ultrasound to evaluate biliary tree for obstruction/cholelithiasis
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