Causes of hypothyroidism in dogs
[DOC File]Kindred Spirits Animal Clinic
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In dogs, the first two causes listed account for almost all cases, although currently the feeling is that atrophy of the gland actually represents the end result of earlier immune-mediated destruction of the gland. Hypothyroidism generally develops in middle aged or elderly dogs.
[DOC File]Wiley
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Familial (runs in certain families or lines of dogs) low levels of thyroid hormone due to infiltration of lymphocytes into the thyroid gland resulting in destruction of thyroid tissue (lymphocytic hypothyroidism) reported in borzois—prolonged interval between “heat” or “estrous” cycles, poor conception rates, abortion mid-pregnancy or gestation, stillbirths
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This is called lymphocytic thyroiditis and is one of the most common causes of primary hypothyroidism in dogs. Degeneration of the thyroid tissue due to cell death (necrosis) or reduced tissue mass (atrophy) is also a common cause of hypothyroidism.
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Panciera DL. Clinical manifestations of canine hypothyroidism. Vet Med 92: 44-49, 1997. Peterson ME, Melian C, Nichols R. Measurement of serum total thyroxine, triiodothyronine, free thyroxine, and thyrotropin concentrations for diagnosis of hypothyroidism in dogs. J Am Vet Med Assoc 211:1396-1402, 1997. Dodds WJ.
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The two main causes for primary hypothyroidism are lymphocytic thyroiditis and idiopathic atrophy of the thyroid glands (Nelson & Couto, 2003). Lymphocytic thyroiditis is responsible for approximately 50% of canine primary hypothyroidism. It is characterized by infiltration of the thyroid gland with macrophages, lymphocytes and plasma cells.
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In rare cases, hypothyroidism can be due to other underlying problems such to a problem with the control centres in the brain, a congenital defect or spread of a tumour from elsewhere in the body. There seem to be certain breeds that are more prone to hypothyroidism such as the Golden Retriever and the Doberman pinscher.
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Inadequate levels of thyroid hormone (known as “hypothyroidism”)—some thyroid disorders appear to be inherited in female dogs and have specific effects on the “heat” or “estrous” cycles; the effect of hypothyroidism on male fertility is less clearly defined and probably is minimal. Signalment/Description of Pet. Species. Dogs
[DOC File]Pituitary Dwarfism - A bigger problem than expected
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It is also well known that hypothyroidism is one of the most common medical causes of aggression or abnormal behaviour in dogs, and dwarf dogs are no exception - some can become aggressive over what would be considered rather trivial issues in normal dogs - …
[DOC File]Michele Wilkinson, wilkinson@cvm
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88. Hypothyroidism causes clinical signs in many organ systems. What metabolic, neurologic, and dermatologic abnormalities are seen with this disease? 89. What breeds of dogs seem to have an higher incidence of hypothyroidism as compared to other breeds? 90. True or False. The measurement of serum T3 levels is a good indicator of hypothyroidism ...
[DOC File]Mood swings and unexplained aggression can be caused by ...
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Dogs may suffer from low thyroid due to a number of causes. Owners should be aware that it is an inheritable trait; Dr. Dodds has observed numerous cases of hypothyroid running in certain families in certain breeds – something breeders of affected animals would rather not hear.
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