Ceftriaxone po conversion
[PDF File] Guideline/Protocol Title: Enterobacterales Bloodstream …
http://5y1.org/file/22151/guideline-protocol-title-enterobacterales-bloodstream.pdf
Dosing based on adjusted body weight (AdjBW) 70-89 kg. 2 DS PO BID. Trimethoprim-sulfamethoxazole (TMP/SMX) 8-10 mg/kg/day (doses divided into 2-3 doses) Double strength (DS) = 160/800 (TMP/SMX) Avoid use in patients who are on warfarin unless there is close monitoring plan of the INR.
[PDF File] Last Approval Date: Policy Title: Pharmacist-Managed …
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on b. pharmacists within the guidelines established in this policy/protocol.II.III.Intravenous (IV) to oral (PO) therapy interchange programs are ofte. used in hospital settings to promote cost-effective utilization of medications. Studies have also shown that appropriate conversion from IV to PO antimicrobial therapy can decrease the length of ...
[PDF File] IV to PO Pharmacy Conversion Protocol - FormWeb
http://5y1.org/file/22151/iv-to-po-pharmacy-conversion-protocol-formweb.pdf
recommending switch to PO ^^Refer to Renal Dosing Protocol for indication-based dosing and adjustments Ampicillin/Sulbactam 1.5 - 3g Q6h Amox/clav 875mg/125mg Q12h Cefazolin 1 - 2 g Q8h Q12-24h Cephalexin 500 mg Q6h Q8 - 12h Ceftriaxone 1 - 2 g Q24h Cefdinir 300mg Q12h TMP-SMX # 5-20mg/kg Divided q6-24h TMP-SMX Same dose Same
[PDF File] 2020 Antimicrobial Stewardship Program Adult Dosing …
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(PO) 300 mg PO QID 300 mg PO TID 300 mg PO BID Dose as per CrCl less than 10 with 1 dose given AD on dialysis days Dose as per CrCl less than 10 Consider upper limit of normal dosing (e.g. up to 600 mg PO QID) Piperacillin/ Tazobactam (Reassess after 72 hours) 3.375 g IV q6h or 4.5 g IV q6 to 8h 20 to 40: 2.25 to 3.375 g IV q6h less than 20: 2 ...
[PDF File] IV to PO Antibiotic Step-Down Guidelines - University of Rhode …
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IV to PO Antibiotic Step-Down Guidelines. Candidates for Antimicrobial Step -Down therapy: • Patient is able to tolerate PO medication . AND. has a functioning GI tract • The infection is treatable with oral antimicrobial therapy . AND. the indications and spectrum of activity are identical or similar between alternative drugs
[PDF File] IV to Oral Switch Clinical Guideline for Adult Patients: Can ...
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The table in Box 3 also provides a guide for selection of the appropriate oral agent. It is important that the clinician reviews any microbiology results available prior to the change. When selecting an antimicrobial it is recommended that the clinician follow the antimicrobial creed of. MINDME:1. M.
[PDF File] Ceftriaxone for Injection, USP - Food and Drug Administration
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Ceftriaxone is a bactericidal agent that acts by inhibition of bacterial cell wall synthesis. Ceftriaxone has activity in the presence of some beta-lac - tamases, both penicillinases and cephalosporinases, of Gram-negative and Gram-positive bacteria. Mechanism of Resistance: Resistance to ceftriaxone is primarily through hydrolysis by beta-lac -
[PDF File] Stanford Health Care Antimicrobial Dosing Reference Guide
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500 mg PO q24h Pseudomonas, severe 400 mg IV q8h 750 mg PO q12h 400 mg IV q8–12h 500 mg PO q12h 400 mg IV q24h 500 mg PO q24h 200 – 400 mg IV q24h 250 – 500 mg PO q24h . Dose daily, but after HD on HD days. 400 mg IV q12h 500 mg PO q12h Severe infection with . A.baumannii. or . P.aeruginosa: 400 mg IV q8-12h . Clindamycin (IV/PO) 1,2
[PDF File] Converting from Intravenous to Oral Antibiotic Therapy
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Appropriate conversion from IV to PO antibiotic therapy can result in several significant benefits: Reducing the risk of intravascular catheter or line infection. Improved patient comfort and mobility. Decreased length of stay. Reduced nursing preparation and administration time. Reduced medication and supply costs.
[PDF File] Clinical Practice Standard 1-20-6-1-010 TITLE: INTRAVENOUS …
http://5y1.org/file/22151/clinical-practice-standard-1-20-6-1-010-title-intravenous.pdf
Ceftriaxone 1 to2 g IV q24h Ciprofloxacin 500 to 750 mg PO BID +/- Cephalexin 500 mg PO QID Cipro = 70% Cephalexin = 90% ... Pharmacist –initiated IV to PO conversion program of antimicrobials. 290.914.916.010. Sun Country Health Region. (2014, September). Integrated and Primary Care. Step-
[PDF File] ADULT ANTIMICROBIAL DOSING GUIDELINE# - Infectious …
http://5y1.org/file/22151/adult-antimicrobial-dosing-guideline-infectious.pdf
CRRT: 6mg/kg IV Q24h Alt: 8 – 10mg/kg IV Q48h. No renal dose adjustment HD: 500mg IV x1 now, then QPM *For outpatient post-HD dosing, contact ID/ASP CRRT: 1g IV Q24h No renal dose adjustment HD: 100mg-400mg* IV/PO x1 now & post-HD CRRT: 200mg-800mg* IV Q24h Severe, CRRT: 800mg -1200mg IV divided q12h-24h.
[PDF File] Intravenous to Oral (IV:PO) Anti-Infective Conversion Therapy
http://5y1.org/file/22151/intravenous-to-oral-iv-po-anti-infective-conversion-therapy.pdf
IV:PO conversion a desirable treat-ment option. Several factors play a role in the scientific basis of IV:PO con-version. These include (1) newer concepts of antimicrobial pharma-codynamic action and the realiza-tion that this can be achieved by oral agents, (2) the advent of newer, more potent, broad-spec-trum oral agents that achieve high-
[PDF File] Eligibility for IV-to-PO Inclusion criteria for IV-to-PO Exclusion ...
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Additional Antimicrobial therapy inclusion criteria. Must satisfy above criteria. Afebrile (< 100.4 ̊F in the last 24 hours) WBC < 11,000 cells/μL. Received ≥ 24 hours of IV antibiotics. Documentation of clinical improvement. Infection does not require IV antibiotics*. Exclusion criteria for IV-to-PO. Nausea/vomiting or diarrhea.
[PDF File] PO Alternatives to Commonly Prescribed IV Antibiotics (Those …
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PO alternatives are indication- and organism-dependent. IV Antibiotic Possible PO Alternative(s)* ... Ceftriaxone (Rocephin) -Cefuroxime (Ceftin)—Use for pneumonias ... Intravenous Medication Oral Conversion Levofloxacin 750mg IV Levofloxacin 750mg PO
[PDF File] SHC “Tips” for Discharging Patients on Parenteral Antibiotics
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Master Reference Table for Outpatient Antibiotics (IV or PO if anticipate extended duration) Dosing Considerationsa Monitoring Considerationsb Drug Consider Oral Therapy (Direct IV to PO Conversion) Once-daily Injection (Select Cases) Intravenous Push (IVP), Programmed Intermittent (PI) Infusion, or Continuous Infusion (CI) Post-HD Injection
[PDF File] Ceftriaxone for Injection, USP
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Bulk Package bottles containing sterile ceftriaxone sodium, USP equiv-alent to 10 grams of ceftriaxone and is intended for intravenous infusion only. Ceftriaxone sodium contains approximately 83 mg (3.6 mEq) of sodium per gram of ceftriaxone activity. A Pharmacy Bulk Package is a container of a sterile preparation for par-
[PDF File] Project Switch Oral Antibiotics Fact Sheet - Ministry of Health
http://5y1.org/file/22151/project-switch-oral-antibiotics-fact-sheet-ministry-of-health.pdf
Suggested PO conversion* Ampicillin/Amoxicillin 25-50 mg/kg/dose 6-hourly Amoxicillin 15-25 mg/kg/dose 8-hourly Benzylpenicillin 30-60 mg/kg/dose 6-hourly Amoxicillin (dose as above) OR Phenoxymethylpenicillin 10-12.5 mg/kg/dose 6-hourly Cefotaxime (restricted) 25-50 mg/kg/dose 6-to-8-hourly Amoxicillin-Clavulanic acid (Augmentin Duo400®)
[PDF File] Conversion from IV to Oral Antibiotics Guidelines
http://5y1.org/file/22151/conversion-from-iv-to-oral-antibiotics-guidelines.pdf
NSIDER CONVERSION FROM IV TO ORAL ANTIBIOTIC. temperature <38°C or improving over 24 hrs. signs & symptoms improved or resolved. oral / nasogastric intake tolerated & absorbed. no diagnostic indication for IV therapy eg. endocarditis, febrile neutropenia, S. aureus bacteraemia, meningitis, osteomyelitis. suitable oral alternative available.
[PDF File] ROCEPHIN (ceftriaxone sodium) FOR INJECTION Rx only …
http://5y1.org/file/22151/rocephin-ceftriaxone-sodium-for-injection-rx-only.pdf
The chemical formula of ceftriaxone sodium is C18H16N8Na2O7S3•3.5H2O. It has a calculated molecular weight of 661.59 and the following structural formula: Rocephin is a white to yellowish-orange crystalline powder which is readily soluble in water, sparingly soluble in methanol and very slightly soluble in ethanol.
[PDF File] Automatic IV to PO Conversion Protocol - ADSP
http://5y1.org/file/22151/automatic-iv-to-po-conversion-protocol-adsp.pdf
Automatic IV to PO Conversion Protocol Purpose: To allow for the conversion of intravenous medications to oral equivalents when medically appropriate in an effort to reduce line-associated risk, reduce nosocomial-acquired infection risk, improve patient satisfaction, promotes earlier and easier ambulation, and reduce
[PDF File] Stanford De-escalation Guide for Gram-negative Bacteremia
http://5y1.org/file/22151/stanford-de-escalation-guide-for-gram-negative-bacteremia.pdf
• Ceftriaxone 2g IV q24h ... • TMP-SMX 2DS PO BID or 8-10mg TMP/kg/day PO divided in 2 or 3 doses 3: rd: line oral alternatives: Data supports stepdown to oral beta-lactams in uncomplicatedbacteremia. 13, 21: Higher than usual doses are recommended to achieve target attainment, especially if organism has a
[PDF File] Skin and Soft Tissue Infections: Treatment Guidance
http://5y1.org/file/22151/skin-and-soft-tissue-infections-treatment-guidance.pdf
• Cephalexin 500mg PO q6h . OR • Dicloxacillin 500mg PO q6h. Severe Penicillin Allergy: Clindamycin 300 mg PO q8h . Moderate-severe • Cefazolin 2g IV q8h . OR • Oxacillin 2g IV q6h. Severe Penicillin Allergy: Clindamycin 600 mg IV q8h. Severe systemic illness or no response/worsening at 48 hours • Consider vancomycin 10-15 mg/kg IV ...
[PDF File] Antimicrobial Stewardship Strategy: Intravenous to oral …
http://5y1.org/file/22151/antimicrobial-stewardship-strategy-intravenous-to-oral.pdf
As a general principle, patients must be monitored by the health care team after changes to therapy resulting from recommendations made by the antimicrobial stewardship team. Intravenous to oral conversion (IV to PO) involves a policy or guideline for switching the route of administration after careful patient assessment.
[PDF File] Conversion Table for IV antibiotics and antifungals to PO
http://5y1.org/file/22151/conversion-table-for-iv-antibiotics-and-antifungals-to-po.pdf
Medication IV Dosage PO Dosage Azithromycin Azithromycin 500 mg q24h 250 mg q24h 500 mg q24h 250 mg q24h Ciprofloxacin Ciprofloxacin 200 mg q12h 400 mg q12h 250 mg q12h ... Conversion Table for IV antibiotics and antifungals to …
[PDF File] Empiric Antibiotic Guidelines for Common Infections in Adults
http://5y1.org/file/22151/empiric-antibiotic-guidelines-for-common-infections-in-adults.pdf
Ceftriaxone* + Doxycycline 100mg PO BID x 7 days *Ceftriaxone dose: ≥150kg: 1g IM x 1 dose <150kg: 500mg IM x 1 dose Gentamicin 240mg IM x 1 + Azithromycin 2,000mg PO x 1 None ΔTrue allergy to beta -lactams: True and severe drug allergies to penicillin and beta lactam antibiotics are rare. Please investigate allergy history thoroughly prior ...
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