Ceftriaxone to po switch
[PDF File] IV to Oral Switch Clinical Guideline for Adult Patients: Can ...
http://5y1.org/file/22075/iv-to-oral-switch-clinical-guideline-for-adult-patients-can.pdf
A large number of clinical trials support the early switching to oral antimicrobials after this period of time with equal treatment efficacy and no adverse effects on patient outcome.3,8-10 The flow chart in this guideline aids the clinician in deciding if it is safe to switch a patient to oral antimicrobials.
[PDF File] IV to ORAL SWITCH & 5 DAY STOP POLICY - Doncaster and …
http://5y1.org/file/22075/iv-to-oral-switch-5-day-stop-policy-doncaster-and.pdf
IV to Oral Switch of Antibiotics All intravenous antibiotics should be reviewed after 48 hours and daily thereafter, and this should be documented clearly in the medical notes. If the patient has been afebrile for 24 hours and shown significant improvement, then an IV to oral switch should be considered. See chart on next page.
[PDF File] PO Alternatives to Commonly Prescribed IV Antibiotics (Those …
http://5y1.org/file/22075/po-alternatives-to-commonly-prescribed-iv-antibiotics-those.pdf
The following alternatives are not automatic switches per the IV to PO policy due to either poor oral bioavailability or lacking in antimicrobial coverage compared to the IV ... Ceftriaxone (Rocephin) -Cefuroxime (Ceftin)—Use for pneumonias -Cephalexin (Keflex)—Use for susceptible UTIs
[PDF File] Severe Sepsis and Septic Shock Antibiotic Guide - Stanford …
http://5y1.org/file/22075/severe-sepsis-and-septic-shock-antibiotic-guide-stanford.pdf
Pneumonia • Ceftriaxone 2g IV q24H plus Azithromycin 500mg IV q24h entry) + vancomycin 15mg/kg • Ceftriaxone 2g IV q24H plus Doxycycline 100mg IV Q12H • Levofloxacin 750mg IV q24h +/- Vancomycin Loading Dose (existing EPIC Urinary Tract Infection • Ertapenem 1g IV q24h • Aztreonam 2g iv q8h
[PDF File] Antibiotics: IV to Oral - Australian Commission on Safety and …
http://5y1.org/file/22075/antibiotics-iv-to-oral-australian-commission-on-safety-and.pdf
Benefits of Early Switch to Oral Therapy. Decreased risk of complications from IV lines: thrombophlebitis, catheter related infections. More patient friendly (improves mobility and comfort) May lead to earlier discharge. Saves medical and nursing time. Reduction in costs: Direct ‐ medication Indirect – diluents, equipment, needles.
[PDF File] Adult IV to Oral Antibiotic Switch Therapy Guidelines
http://5y1.org/file/22075/adult-iv-to-oral-antibiotic-switch-therapy-guidelines.pdf
Make the switch to oral therapy Switch to oral therapy (usually for 5 - 7 days) • Check contra-indications, ADRs and potential drug interactions in BNF • Change on medicine chart • Remove IV cannula if not required Switch to Oral Therapy - Check empirical guidelines first for recommended switch. If no oral switch given, the
[PDF File] Inpatient Empiric Antibiotic Recommendations for Adults1
http://5y1.org/file/22075/inpatient-empiric-antibiotic-recommendations-for-adults1.pdf
Use alternative regimen replacing β-lactam base with 1 of the following based on P. aeruginosa risk: If anti-pseudomonal coverage not required: *Ampicillin-sulbactam 3 gm IV q 6 hrs. -OR-. If anti-pseudomonal coverage required: *Piperacillin-tazobactam 4.5 gm IV q 8 hrs. Select regimens as above and add Metronidazole 500 mg IV q 12 hrs.
[PDF File] Conversion from IV to Oral Antibiotics Guidelines
http://5y1.org/file/22075/conversion-from-iv-to-oral-antibiotics-guidelines.pdf
CEFTRIAXONE* 1g daily CEPHAZOLIN 1-2g tds CIPROFLOXACIN* 200-400mg bd CLINDAMYCIN 450-600mg tds FLUCLOXACILLIN 1-2g qid FLUCONAZOLE* 100-400mg daily METRONIDAZOLE 500mg bd MOXIFLOXACIN* 400mg daily TAZOCIN®* 4.5g tds TIMENTIN® 3.1g qid AMOXYCILLIN 1-2g qid plus GENTAMICIN 5mg/kg/day IV TO …
[PDF File] Intravenous Antibiotic - Oral Switch Therapy (IVOST) Protocol
http://5y1.org/file/22075/intravenous-antibiotic-oral-switch-therapy-ivost-protocol.pdf
Indications to Continue IV Therapy. Continuing serious sepsis (2 or more of the following) temp > 38°C or < 36°C. tachycardia ≥ 90/min. tachypnoea > 20 breaths/min. WCC > 12 or < 4. Febrile with neutropenia (WCC <1.0) or immunosuppression. Specific infections which require high dose IV therapy eg endocarditis, septic arthritis ...
[PDF File] Tonsillitis & pharyngitis, peritonsillar abscess, bacterial …
http://5y1.org/file/22075/tonsillitis-pharyngitis-peritonsillar-abscess-bacterial.pdf
Unable to tolerate oral antibiotics (consider early IV to PO switch): Ceftriaxone IV 5 days Penicillin allergic: Clarithromycin IV 5 days ANY RED FLAGS? - <3 month old with fever >38 ... Consider IV to PO switch: First line switch: Co-amoxiclav PO 7-10 days total course Penicillin allergic: Clindamycin PO 7-10 days total course ...
[PDF File] IV to Oral Switch Clinical Guideline for Adult Patients: Can ...
http://5y1.org/file/22075/iv-to-oral-switch-clinical-guideline-for-adult-patients-can.pdf
A large number of clinical trials support the early switching to oral antimicrobials after this period of time with equal treatment efficacy and no adverse effects on patient outcome.3,8-10 The flow chart in this guideline aids the clinician in deciding if it is safe to switch a patient to oral antimicrobials.
[PDF File] Antimicrobial Stewardship Program Empiric Treatment …
http://5y1.org/file/22075/antimicrobial-stewardship-program-empiric-treatment.pdf
100 mg PO BID or 2. Ceftriaxone 2 g IV q24h + Doxycycline** 100 mg PO BID [**alt = Azithro € 500 mg PO/IV daily x 3 days] Step down to PO for total duration of 7 days CAP Inpatient Severe (ICU) CURB-65: score 3 to 5 €Consider baseline ECG to assess QTc As Above 1. Ceftriaxone 2 g IV q24h x 7 days + Azithro€ 500 mg IV/PO daily x 3 days or 2.
[PDF File] Intravenous to Oral (IV:PO) Anti-Infective Conversion Therapy
http://5y1.org/file/22075/intravenous-to-oral-iv-po-anti-infective-conversion-therapy.pdf
“switch,” “sequential,” and “step-down”therapy.1-3For the purposes of this review, the concept is referred to as IV:PO conversion. Rationale Clinical trials have been conducted that demonstrate the efficacy and safety of IV:PO con-version,4-12and several studies have addressed the economic impact of conversion.4,7,9-12 Cost savings may
[PDF File] IV to PO Antibiotic Step-Down Guidelines - University of …
http://5y1.org/file/22075/iv-to-po-antibiotic-step-down-guidelines-university-of.pdf
IV to PO Antibiotic Step-Down Guidelines. Candidates for Antimicrobial Step -Down therapy: • Patient is able to tolerate PO medication . AND. has a functioning GI tract • The infection is treatable with oral antimicrobial therapy . AND. the indications and spectrum of activity are identical or similar between alternative drugs
[PDF File] Intravenous Antibiotic - Oral Switch Therapy (IVOST) Protocol
http://5y1.org/file/22075/intravenous-antibiotic-oral-switch-therapy-ivost-protocol.pdf
Monitor patient’s progress following change to oral therapy (refer to Box 1) Box 2. Indications to Continue IV Therapy. • Continuing serious sepsis (2 or more of the following) - temp > 38°C or < 36°C. - tachycardia > 90/min. - tachypnoea > 20 breaths/min. - WCC > 12 or < 4. • Febrile with neutropenia (WCC <1.0)
[PDF File] Antimicrobial Stewardship Program Perspective: IV-to-PO …
http://5y1.org/file/22075/antimicrobial-stewardship-program-perspective-iv-to-po.pdf
nsitional antibiotic therapy,” now known as IV-to-PO switch therapy. Early experience with this therapy demonstrated that some or most antibiotic therapy in hospital could be transitioned to PO following initial IV therapy.3,4 It became clear that patients treated with IV-to-PO therapy for common infec-tious diseases, e.g., community acquired ...
[PDF File] Antibiotics: IV to PO Stepdown - VCH
http://5y1.org/file/22075/antibiotics-iv-to-po-stepdown-vch.pdf
Ceftriaxone; Pneumonia; Amoxicillin 500mg PO TID . OR. Cefuroxime 500mg PO TID. Biliary. ... Ciprofloxacin 500 mg PO BID + Clindamycin 600 mg PO TID. Vancomycin. MRSA ... If your patient is receiving IV antibiotics, consider a switch to oral if: Patient is . clinically improving, with ≥2 of: • Afebrile • HR <90 beats per minute
[PDF File] IV to PO Pharmacy Conversion Protocol - FormWeb
http://5y1.org/file/22075/iv-to-po-pharmacy-conversion-protocol-formweb.pdf
recommending switch to PO ^^Refer to Renal Dosing Protocol for indication-based dosing and adjustments Ampicillin/Sulbactam 1.5 - 3g Q6h Amox/clav 875mg/125mg Q12h Cefazolin 1 - 2 g Q8h Q12-24h Cephalexin 500 mg Q6h Q8 - 12h Ceftriaxone 1 - 2 g Q24h Cefdinir 300mg Q12h TMP-SMX # 5-20mg/kg Divided q6-24h TMP-SMX Same dose Same
[PDF File] Project Switch Oral Antibiotics Fact Sheet - Ministry of Health
http://5y1.org/file/22075/project-switch-oral-antibiotics-fact-sheet-ministry-of-health.pdf
Phenoxymethylpenicillin 10-12.5 mg/kg/dose 6-hourly. Cefotaxime (restricted) 25-50 mg/kg/dose 6-to-8-hourly. Amoxicillin-Clavulanic acid. (Augmentin Duo400®) 22.5 mg/kg/dose (amoxicillin component) 12-hourly If treating a Pseudomonas or resistant Gram negative infection, seek ID advice. Amoxicillin-Clavulanic acid.
[PDF File] Inpatient Management of Febrile Neutropenia in Adult …
http://5y1.org/file/22075/inpatient-management-of-febrile-neutropenia-in-adult.pdf
Voriconazole 400 mg PO q12hr x 2, then 200 mg PO q12hr Alternative: Alternatives include amphotericin, isavuconazole, posaconazole, or caspofungin. Selection should be based on radiographic imaging and made in consultation with ICHS Heme/BMT consult service If concern for mucormycosis: Liposomal amphotericin B 5 mg/kg IV daily No
[PDF File] Antimicrobial treatment: Early intravenous to oral switch
http://5y1.org/file/22075/antimicrobial-treatment-early-intravenous-to-oral-switch.pdf
Introduction. Initially, giving antimicrobials by the intravenous (IV) route may be preferable in severe infection. However, in the majority of patients who are clinically improved and adequately absorbing oral drugs, administration can be switched to the oral route after 48 hours of IV therapy. This is known as the IV to oral switch.
[PDF File] Antibiotic Guidelines 2020 - North Bristol NHS Trust
http://5y1.org/file/22075/antibiotic-guidelines-2020-north-bristol-nhs-trust.pdf
Antibiotic Guidelines 2020. These are empirical guidelines – treatment should be reviewed clinically at 48-72 hours with the results of clinical findings, pathology and imaging results, and microbiological cultures. Antimicrobials can then be stopped, switched to oral therapy, changed to a narrow spectrum agent or continued with further review.
[PDF File] ADULT ANTIMICROBIAL DOSING GUIDELINE# - Infectious …
http://5y1.org/file/22075/adult-antimicrobial-dosing-guideline-infectious.pdf
CRRT: 6mg/kg IV Q24h Alt: 8 – 10mg/kg IV Q48h. No renal dose adjustment HD: 500mg IV x1 now, then QPM *For outpatient post-HD dosing, contact ID/ASP CRRT: 1g IV Q24h No renal dose adjustment HD: 100mg-400mg* IV/PO x1 now & post-HD CRRT: 200mg-800mg* IV Q24h Severe, CRRT: 800mg -1200mg IV divided q12h-24h.
[PDF File] Guideline/Protocol Title: Enterobacterales Bloodstream …
http://5y1.org/file/22075/guideline-protocol-title-enterobacterales-bloodstream.pdf
Dosing based on adjusted body weight (AdjBW) 70-89 kg. 2 DS PO BID. Trimethoprim-sulfamethoxazole (TMP/SMX) 8-10 mg/kg/day (doses divided into 2-3 doses) Double strength (DS) = 160/800 (TMP/SMX) Avoid use in patients who are on warfarin unless there is close monitoring plan of the INR.
[PDF File] Stanford Antimicrobial Safety and Sustainability Program …
http://5y1.org/file/22075/stanford-antimicrobial-safety-and-sustainability-program.pdf
Ceftriaxone 2g IV q24h + metronidazole 500mg PO/IV q8h If stable for outpatient management: Amoxicillin-clavulanate 875/125mg PO TID • Alternative regimen: Ciprofloxacin 500mg PO BID or 400mg IV q12h + metronidazole 500mg PO/IV q8h : 5 - 7 days: 4 *Absence of oncologic or hematologic malignancy, HIV with low CD4 (<200) , …
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