Cholesterol transport pathways
Understanding the Essentials of Blood Lipid Metabolism
High-density lipoprotein (HDL) plays an essential role in plasma lipid transport. HDL is also the major vehicle for the transport of cholesterol from peripheral cells to the liver for excretion and catabolism. This process, known as reverse cholesterol transport (Fig. 4.), occurs in three stages: extravascular, intravascular, and intrahepatic.
[DOC File]Introduction to Cholesterol Metabolism
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Importantly, monensin did not prevent transport of CTB to GA in Balb3T3 cells, but it prevented transport to lysosomes and degradation. Conclusion From these results we can conclude that CTB enters Balb3T3 cells mainly via cholesterol dependent endocytic pathway, while in HeLa cells both clathrin and cholesterol dependent pathways have ...
[DOC File]CHOLERA TOXIN USES MULTIPLE TRAFFICKING PATHWAYS …
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Defect or changes in the pathways of lipid metabolism are directly related to development of diseases. ... Transport and storage of triglycerides are affected in obesity, diabetes and hyper lipoproteinemia. ... containing cholesterol and triglycerides that transport lipids out of the intestinal cells and into the lymphatic and circulatory systems.
[DOCX File]C O N T E N T
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Cholesterol Metabolism. Cholesterol is present in tissues and in plasma either as free cholesterol or as a storage form, combined with along-chain fatty acid as cholesteryl ester. In plasma, both forms are transported in lipoproteins . Functions of Cholesterol. Cholesterol is an amphipathic lipid and as such is an essential structural 1.
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