Chronotropic agents
[DOC File]Lecture #1 - Jewish Hospital Cardiothoracic Surgical ...
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D. Cardioactive Agents. Inotropic – effect the contractility of the heart (myocardium) Chronotropic – effect the conduction rate of the heart (pacemaker) Example-1: positive inotropic effect will increase force of contraction. Example-2: negative chronotropic effect will decrease heart rate. E. Cell Receptors
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Regitine produces an alpha-adrenergic block of relatively short duration. It also has direct, but less marked, positive inotropic and chronotropic effects on cardiac muscle and vasodilator effects on vascular smooth muscle.
[DOC File]Lecture #1 - Jewish Hospital Cardiothoracic Surgical ...
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D. Cardioactive Agents. Inotropic – effect the contractility of the heart (myocardium) Chronotropic – effect the conduction rate of the heart (pacemaker) ...
[DOCX File]Acute Spinal Cord Injury 2018
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Evans CH, Duby JJ, Berry AJ, et.al. Enteral albuterol decreases the need for chronotropic agents in patients with cervical spinal cord injury – induced bradycardia. J …
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Negative Inotropic, Chronotropic and Dromotropic Agents. Non-Selective Beta Blocker – Propanolol . Contraindication . Asthma . COPD . Heart block . Peripheral heart disease . Blocks both Beta 1 and Beta 2 receptors . If Channel Blocker – Ivabradine . Block the HCN channel/ Funny channel.
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Cardiotonic mechanism of action of cardiac glycosides. Influence of cardiac glycosides on the main functional indexes of the heart (positive inotropic, positive batmotropic, negative dromotropic, negative chronotropic, positive tonotropic and mechanisms of these phenomena). Systolic and diastolic effects. ECG changes caused by cardiac glycosides.
[DOC File]ICU SEDATION GUIDELINES
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It exerts its effects primarily through stimulation of cardiac beta1 receptors, resulting in potent inotropic activity with weaker chronotropic activity. On vascular smooth muscles, dobutamine (at lower doses) can decrease SVR as a result of reflex vasodilation and beta2 receptor activation leading to significant hypotension (18).
MCQ 1
7. The following are true of alpha-adrenoceptor blocking agents: a) they increase blood flow in normal skin and muscle b) they cause drowsiness c) the clinically useful drugs are competitive antagonists d) they have only alpha 1- blocking activity e) they are chronotropic agents. 8. In the normal cardiac cycle:
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