Clinical significance definition

    • [PDF File]PDF The "art" Clinical Validation - ACDIS

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      the "art" clinical validation laurie l. prescott rn, msn, ccds, cdip ahima approved icd-10 cm/pcs trainer cdi education specialist -hcpro, a division of blr

    • [PDF File]PDF The Meanings and Measurement of Clinical Significance

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      The Meanings and Measurement of Clinical Significance Alan E. Kazdin Department of Psychology Yale University ABSTRACT The previous articles in this special section make the case for the importance of evaluating the clinical significance of therapeutic change, present key measures and innovative ways in which

    • Gastrointestinal bacterial overgrowth: pathogenesis and ...

      be used as the definition of SIBO (Box 1). What is unique about SIBO is that there are exces - sive numbers of aerobic and anaerobic bacteria Gastrointestinal bacterial overgrowth: pathogenesis and clinical significance Amit H. Sachdev and Mark Pimentel Abstract: Small intestinal bacterial overgrowth (SIBO) is defined as the presence of an

    • Clinical Significance of Hyperkeratosis and Parakeratosis in ...

      To ascertain the clinical significance of hyperkeratosis and par- akeratosis in otherwise negative Papanicolaou smears, we ret- rospectively reviewed 96 patients with these findings seen during a 32-month period. Evaluation included repeating the smear and performing colposcopy in all patients.

    • [PDF File]PDF Clinical Significance: A Statistical Approach to Defining ...

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      Clinical Significance: A Statistical Approach to Defining Meaningful Change in Psychotherapy Research Neil S. Jacobson and Paula Truax University of Washington In 1984, Jacobson, Follette, and Revenstorf defined clinically significant change as the extent to

    • [PDF File]PDF Urinary Tract Infection - What is It? Definition of "UTI"

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      Clinical: bacteria causing dz, need treatment >10 5cfu/mL criterion for "significance" - Microbiological Designed for voided samples in asxpatients to distinguish vaginal and urethral contamination from bacteria truly from the bladder Not informative re. clinical significance of bacteria Unsuited for symptomatic or catheter-associated UTI

    • [PDF File]PDF Statistical significance and statistical power in hypothesis ...

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      Statistical Significance and Statistical Power in Hypothesis Testing Richard L. Lieber Division of Orthopaedics and Rehabilitation, Veterans Administration Medical Center and University of California, Sun Diego, CA, U.S.A. Summary: Experimental design requires estimation of the sample size required to produce a meaningful conclusion.

    • Incidence and Clinical Significance

      mined the incidence and clinical significance of tracheobronchial lacerations after balloon dilation for treatment of benign tracheobronchial strictures. Methods: We evaluated 97 patients who had undergone balloon dilation in 124 sessions for the treatment of benign tracheobronchial strictures. The degree of airway laceration was evaluated

    • PDF Clinical, Significance As It Related to Evidence Based

      definition for clinical significance will enhance its usefulness in research and practice. Methods Rodgers' evolutionary approach to concept analysis provides the framework for interpreting clinical significance in the context ofits uses, measurements, and defInitions in the nursing literature.

    • [PDF File]PDF When Is a Medication Error Clinically Significant?

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      WHEN IS A MEDICATION ERROR CLINICALLY SIGNIFICANT? An important aspect of the long term care survey process consists of evaluating the safety and effectiveness of the facility's system for preparing and administering medications to its residents. This is accomplished by conducting the medication pass observation, otherwise known as "Task 5 ...

    • [PDF File]PDF P Values, Statistical Significance & Clinical Significance

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      P Values, Statistical Significance & Clinical Significance When looking at the results of a research study, a practitioner has to answer two big questions: 1. Were the results due to chance? 2. Are the results big enough to matter to a patient? P values and Statistical Significance

    • [PDF File]PDF Proteinuria and Microalbuminuria in Adults; Significance ...

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      Significance, Evaluation, and Treatment K.K. Venkat, MD ... lection in clinical practice. • Reduction of microalbuminuria in diabetics and overt proteinuria irrespective of etiology, together with strict blood pressure control, is helpful in ameliorating the

    • [PDF File]PDF The Clinical Significance of Relative Bradycardia

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      and lack of a consistent definition used. The fact that this sign is not consistently identified in case series suggests that relative bradycardia is caused by mechanisms presumably involving or influenced by pathogen and host factors. Conclusions: Relative bradycardia is a sensitive but nonspecific clinical sign that may be an

    • [PDF File]PDF Clinical Significance: A Statistical Approach to Denning ...

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      to criteria based on statistical significance, judgments regard-ing clinical significance are based on external standards pro-vided by interested parties in the community. Consumers, clini-cians, and researchers all expect psychotherapy to accomplish particular goals, and it is the extent to which psychotherapy

    • Glossary of Terms on Clinical Trials for Patient Engagement ...

      GLOSSARY OF TERMS ON CLINICAL TRIALS FOR PATIENT ENGAGEMENT ADVISORY COMMITTEE MEETING 1 TERM DEFINITION Assent A child's affirmative agreement to participate in a clinical investigation.

    • PPT Statistical vs Clinical Significance - Sportsci

      "Likely" is usually a probability of 0.95 (defining 95% limits). Clinical Significance Statistical significance focuses on the null value of the effect. More important is clinical significance defined by the smallest clinically beneficial and harmful values of the effect. These values are usually equal and opposite in sign.

    • [PDF File]PDF Monoclonal Gammopathy of Clinical Significance (MGCS)

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      * Monoclonal gammopathy of renal significance: when MGUS is no longer undetermined or significant, Leung N, Bridoux F, et al. Blood 2012 * Monoclonal gammopathy of clinical significance: a novel concept with therapeutic implications, Fermand JP, Bridoux F, et al. Blood 2018 and made recommendations based on expert opinion

    • [PDF File]PDF Differentiating statistical significance and clinical ...

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      Nursing Research 101 Differentiating. statistical. significance. andclinical. significance. ByElizabethHeavey,PhD,RN,CNM . T. O IMPLEMENT. evidence-based practice, nurses must be able to comprehend and interpret research. That means you need to understand the distinction between statistical significance and clinical significance.

    • PDF Statistical versus Practical Significance - The Atrium

      2 If we chose α= 0.05, we are insisting that evidence against H 0 is so strong that it would happen no more than 5% of the time (1 time in 20) when H 0 is true. If we chose α= 0.01, we are demanding even stronger evidence

    • The Usage and Meaning of 'Clinical Significance' in Drug ...

      phrase "clinical significance" several times throughout its opinion, nowhere does it provide any definition or explication. The best indication of the While these standards can be tied only to the word "significant," rather than to the entire phrase "clinical significance," the addition of "clinical" often appears in the Black Lung case

    • [PDF File]PDF Upper Airway Cough Syndrome - Definition, Pathogenesis And ...

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      Upper Airway Cough Syndrome - Definition, Pathogenesis and Clinical Significance. ABSTRACT. Chronic cough is a troublesome problem, which considerably reduces the quality of life of affected individuals. Standardized diagnostic protocols focus mainly to the three most frequent . reasons of chronic cough, so-called diagnostic triad.

    • Clinical significance of free-floating venous thrombi

      Clinical significance venous thrombi of free-floating E. Douglas Baldridge, MD, 1 Michael A. Martin, BS, 2 and Richard E. Welling, MD, 2 Cincinnati, Ohio To evaluate the fate of free-floating venous thrombi, venous duplex scans of 5238 con-

    • PDF Clinical Significance of CD34 Expression in Childhood Acute ...

      Clinical Significance of CD34 Expression in Childhood Acute Lymphoblastic Leukemia By Ching-Hon Pui, Michael L. Hancock, David R. Head, Gaston K. Rivera, A. Thomas Look, John T. Sandlund, and Frederick G. Behm The CD34 antigen was detected on 210% of the blast cells in 235 (70%) of 335 cases of newly diagnosed childhood

    • [PDF File]PDF A Practical Introduction to Clinical Data Acquisition ...

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      A Practical Introduction to Clinical Data Acquisition Standards Harmonization (CDASH) Jennifer Price, Phoenix Data Systems, Inc, King of Prussia, PA ABSTRACT On October 1st, 2008, CDASH released the first 16 common CRF streams (or domains) for use by the Pharmaceutical Industry.

    • Microalbuminuria: Definition, Detection, and Clinical ...

      Microalbuminuria: Definition, Detection, and Clinical Significance Robert D. Toto, MD From the University of Texas Southwestern Medical Center-Dallas, Dallas, TX Address for correspondence: Robert D. Toto, MD, Professor of Medicine, University of Texas Southwestern Medical Center-Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390-8856

    • [PDF File]PDF Clinical Significance 1 Running Head: CLINICAL ... - ERIC

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      Clinical significance is an important concept in research, particularly in education and the social sciences. The present article first compares clinical significance to other measures of "significance" in statistics. The major methods used to determine clinical significance are explained and the strengths and weaknesses of clinical ...

    • Fda Fact Sheet

      Level 3: Cancer Mutations with Potential Clinical Significance. Mutations not considered biomarkers in Level 1 or Level 2 can be described as cancer mutations with potential clinical significance.

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