Clonidine for alcohol withdrawal dosing
[DOCX File]LOWELL GENERAL HOSPITAL
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The general public and many clinicians are of the opinion that treatment for drug and alcohol use is ineffective. In contrast, there is a growing consensus among the research community that treatment does work (Nathan & Gorman, 1998). The aim of this document is to demonstrate the benefit in investing in treatment for alcohol and drug problems.
[DOC File]ALCOHOL WITHDRAWAL: PATHPHYSIOLOGY, DIAGNOSIS …
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Another therapy used is clonidine, an antihypertensive (alpha-2 antagonist) which is also used as an adjunctive agent in alcohol and opiate addiction. It is thought that clonidine is most effective as a second-line agent in nicotine cessation to reduce withdrawal symptoms associated with craving, irritability, anxiety, and restlessness.
[DOC File]Substance Abuse
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The prolonged use of dexmedetomidine (DEX) for sedation can result in withdrawal when the infusion is abruptly discontinued. Enteral clonidine (CLO) has demonstrated success in preventing withdrawal symptoms and facilitating discontinuation of DEX. Various CLO dosing regimens have been utilized for this indication.
alpha2-Agonists for Acute Alcohol Withdrawal
Clonidine can cause sedation and abrupt withdrawal of clonidine can induce profound hypertension. It should be used with extreme caution in patients with intravascular volume depletion. Dexmedetomidine (Precedex®) is a highly selective alpha-2 agonist approved for short term sedation in non-intubated patients.
[DOCX File]ICU SEDATION GUIDELINES
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Clonidine is also used in the treatment of dysmenorrhea (severely painful cramps during menstrual period), hypertensive crisis (a condition in which your blood pressure is very high), Tourette's syndrome (a condition characterized by the need to perform repeated motions or to repeat sounds or words), attention deficit hyperactivity disorder (ADHD), menopausal hot …
[DOCX File]Connecticut Society of Health System Pharmacists - Home
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Predictors of outcome for short-term medically supervised opioid withdrawal during a randomized, multicenter trial of buprenorphine-naloxone and clonidine in the NIDA clinical trials network drug and alcohol dependence. Drug Alcohol Depend, 99 (1-3), 28-36. doi: 10.1016/j.drugalcdep.2008.06.016. Epub 2008 Sep 20.
[DOCX File]The effects of pharmacological treatment with ...
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Infant may continue to receive PRN dosing after transfer. Neonatal morphine should be ordered as 0.05 mg/kg/dose PO q3 hours PRN based on birthweight unless current weight is higher than birthweight. If more than 4 PRN doses are needed in a 24 hours period, begin scheduled morphine dosing as described below.
[DOCX File]Patient Handouts - Redemption Psychiatry, LLC
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Symptom-triggered vsfixed-schedule doses of benzodiazepine for alcohol withdrawal: a randomizedtreatment trial. Arch Intern Med 162: 1117-1121, 2002. 32. Myrick H, Brady KT, Malcolm R.Divalproex in the treatment of alcohol withdrawal. Am J Drug Alcohol Abuse 26: 155-160,2000. Appendix 1.
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