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[PDF File]510(k) SUBSTANTIAL EQUIVALENCE DETERMINATION …
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– A common metabolite that is NOT 1) a separately marketed drug or 2) a manufacturing impurity or 3) a chemical decomposition product or 4) the product of an in vitro chemical reaction on the hair. • Unacceptable candidate marker to show cocaine use: – Benzoylecgonine. • Potentially good candidate marker for codeine:
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[PDF File]How to correctly interpret a urine drug screen result
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The Quest Diagnostics HairCheck-DT (Cocaine) test system utilizes an Enzyme Linked Immunosorbent Assay (ELISA) for the qualitative detection of cocaine in head hair samples through the measurement of cocaine and cocaine metabolites for concentrations at or above 300 pg/mg hair.
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[PDF File]Frequently Asked Questions - Quest Diagnostics
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metabolite morphine may be the only drug detected in a heroin user. ... Cocaine 2 – 4 days Marijuana, single use 3 days Marijuana, daily use 2 weeks ... After the confirmatory test results are available, if discrepancies remain, it is important to have a non-confrontational discussion with the patient about the urine test
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[PDF File]DEPARTMENT OF HEALTH & HUMAN SERVICES
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Frequently Asked Questions Hair Testing Q: Why drug test? A: Employee drug use can put employers at a risk of increased accidents, increased absenteeism, lower productivity, and higher insurance costs. Hair testing, like all drug testing methodologies, helps to mitigate these risks by …
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[PDF File]Quantitative Urine Levels of Cocaine and Other Substances ...
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The Emit® II Plus Cocaine Metabolite Assay is a homogeneous enzyme immunoassay with a 150 ng/mL or 300 ng/mL cutoff (SAMHSA initial test cutoff level).1 The assay is intended for use in the qualitative and semiquantitative analyses of benzoylecgonine (cocaine metabolite) in human urine.
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[PDF File]Interpretation of Opiate Urine Drug Screens
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•A positive test result should not simply lead to discharge from treatment, but an opportunity for reviewing the current plan ... •Cocaine metabolite (benzoylecgonine) What is NOTin a typical screeningtest •Buprenorphine (and nor-buprenorphine) •Fentanyl •Oxycodone •Methadone
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[PDF File]Cocaine Metabolite Assay - Beckman Coulter
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As always, clinical judgment is necessary when interpreting test results. ... Cocaine metabolites 2-4 d Marijuana Single use 3 d Moderate use (4 times/wk) 5-7 d Daily use 10-15 d ... the drug is simply a metabolite of a prescribed drug (as applicable).
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[PDF File]Immunoassay for Detection of Cocaine/Metabolites in Oral ...
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The Quest Diagnostics Urine Cocaine Metabolite EIA is a competitive immunoassay for the qualitative determination of cocaine and cocaine metabolites in urine. Cocaine metabolites in urine and the cocaine metabolite Benzoylecgonine (BE) in the enzyme conjugate compete for the finite binding sites of antibody in solution. If little
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Cocaine Metabolite, Urine (Screen), McLendon Clinical Laboratorie…
example, a patient’s urine level of the cocaine metabolite benzoylecgonine (BE) can range from 0 to 300,000 ng/mL or higher. ... in order to defeat the urine test. A Cn-adjusted level is produced by dividing the concentration (mg/mL) of excreted Cn into the analyte concentration. As …
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[PDF File]Urine drug screening
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The STC Cocaine Metabolite MICRO-PLATE EIA (STC Diag-nostics) is a competitive immunoassay for the detection of co-caine and cocaine metabolites in oral fluid collected with the Intercept collection device. To each microplate well, 50 mL of sample eluate (N = 3), control, or calibrator was added along
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Cocaine metabolite test