Collagen and autoimmune disease
Table S2: Cytoplasmic HEp-2 patterns (further details)
SLI is an autoimmune disorder of unknown etiology. Its varied clinical manifestations are the result of antibodies directed against tissues or cells, or the deposition of immune complexes in tissues or organs. The disease ranges in seriousness from mild and transient to severe and life threatening.
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Collagen. The most common site of cardiac valvular regurgitation are which valves? ... Dry eyes and dry mouth with the symptoms of an autoimmune disease are characteristic of? Rheumatoid arthritis. Reiters syndrome. Sjrogen’s syndrome ... Which class of immunoglobulin most commonly causes autoimmune diseases? Iga and igm. Ige and iga. Igg and ...
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Affinity differences of an immunodominant collagen peptide for IAq and I-Ap control susceptibility to collagen-induced autoimmune arthritis Lymphocyte Activation , Keystone Symposia, p. 86, 1996.
Collagen Vascular Disease: Causes, Symptoms & Treatments
CONNECTIVE-TISSUE (COLLAGEN) DISEASES. Clinical features: Autoimmune disease characterized by necrosis and degeneration of fibrous connective tissue. Clinical features depend on organs affected. LUPUS ERYTHEMATOSUS. A connective-tissue disease of young women. Associated with formation of autoantibodies and immune complexes
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But the same type of collagen (Type IV) forms the middle layer of the respiratory membrane in alveoli, so some patients who have this “anti-glomerular basement membrane disease” have an autoimmune attack of alveoli; this leads to inflammation in the lungs and can cause the alveoli to fill with fluid and blood, that, in turn, can result in ...
[DOC File]Marfan Syndrome: A genetic defect leading to problems in ...
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B. Collagen vascular disease. 1. Pathophysiology. a. Systemic lupus erythematosus (SLE or lupus) i. Suspect in women of childbearing age with fever, rash, and joint pain. ii. Multisystem autoimmune disease that affects the entire body. iii. Care should be directed at monitoring for life threats. iv. Patients may be on immunosuppressive medications.
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Scleroderma: A chronic auto-immune disease in which fibroblasts in the smallest blood vessels produce huge amounts of collagen in the skin and other tissues. Damage to these tiny vessels causes local edema and the stimulation of nearby fibroblasts.
Ohio University
Autoimmune disease Etiology: Antibodies to 3 chain of type 4 collagen present in the basement membrane Pathogenesis: Type II hypersensitivity due to antibodies that cause destruction of the basement membrane in areas with small capillary beds such as the lung and the glomerulus.
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is a multi-system inflammatory disease, probably autoimmune in nature, which affects the heart, joints, skin, and CNS. ... is an inflammatory lesion associated with swelling and fragmentation of collagen fibers and alterations in the staining characteristics of connective tissue. Treatment. Carditis with …
[DOC File]Pediatrics—Acquired Heart Disease
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Reported with relatively high prevalence (~40%) in patients with AIH type 1 and associated with more severe disease, clinical and histological disease activity, predictor of therapeutic response, and double positivity with anti-ssDNA antibodies
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