Concentric vs eccentric cardiac hypertrophy
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Explain the following contraction types: isotonic concentric, isotonic eccentric, isometric, isokinetic. Explain what changes occur in the muscular system in response to physical activity. The Cardiovascular System
[DOC File]Heart failure and PAH - Chest
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Overexpression of SRF without external stimuli is sufficient to cause eccentric hypertrophy and heart failure. In addition to its direct effects on the expression of transcription factors, calmodulin regulates Ca2+ handling and E-C coupling via LTCCs, RyR and SERCA, with a recent report demonstrating early cardiac hypertrophy in mice with ...
[DOC File]Adverse Left Ventricular Remodeling, Incident Heart ...
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In eccentric geometry with increased LV mass (eccentric LVH, n=191) incident heart failure (IHF) was more common (37 vs 29%, p=0.02) than in eccentric geometry without LVH (n= 286). In concentric geometry and LVH (concentric LVH, n=223), IHF was more common (32 vs 16%, p= 0.001) than in those without LVH (n=2481).
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Overloads in both pressure and volume change the geometry of the heart chambers; these changes can be either concentric or eccentric (Dorn, 2007). Pathological cardiac hypertrophy is not reversible and ultimately leads to decreased cardiac function and heart failure (Chung & Leinwand, 2014; Dorn, 2007).
[DOCX File]ABSTRACT - American Society of Exercise Physiologists :: Home
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Morganroth et al. (104) suggested that eccentric hypertrophy adaptation (i.e., proportional increase in ventricle chamber size and LV wall thickness) is a product of a high cardiac output while concentric hypertrophy characterized by an increased ratio of wall thickness to radius appears as a product of the volume of blood pumped, which might ...
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Mihl C, Dassen WR, Kuipers H. Cardiac remodelling: concentric versus eccentric hypertrophy in strength and endurance athletes. Neth Heart J. 2008; 16: 129-33. Pluim BM, Zwinderman AH, van der Laarse A, et al. The athlete's heart. A meta-analysis of cardiac structure and function. Circulation. 2000; 101: 336-44.
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