Continuous infusion vancomycin dosing
University of Wisconsin Hospital and Clinics
During each admission, patients were randomized to one of three dosing regimens. The 13.5g continuous infusion regimen consistently resulted in higher concentrations above the breakpoint for K. pneumoniae and many of the susceptible strains of P. aeruginosa than did the 6.75g continuous infusion (6). (Class II) Vancomycin
jdc.jefferson.edu
Nephrotoxic agents include frusemide, vancomycin, amphotericin, cisplatin, other aminoglycosides, aciclovir, regular use of NSAIDs . ... In vitro, once daily dosing results in lower renal cortical concentrations compared to continuous infusions or traditional dosing and it is therefore hypothesised that once daily dosing may lessen nephrotoxicity.
[DOCX File]Home Page: Clinical Microbiology and Infection
https://info.5y1.org/continuous-infusion-vancomycin-dosing_1_bfda4d.html
Factors that influence vancomycin dose requirements in neonates and young infants were used to create guidelines for vancomycin administration by intermittent infusion (Reference 3). Simulations based on this and other population models led to new guidelines that were designed to achieve target vancomycin concentrations using a continuous ...
[DOCX File]Gentamicin - Clinical Guidelines for Dosing and Monitoring ...
https://info.5y1.org/continuous-infusion-vancomycin-dosing_1_cd5dcd.html
Typical vancomycin pharmacokinetics following the first dose of vancomycin administered to a standard patient (male, 50 years old, body weight: 75 kg, body height: 1.7 m, serum creatinine of 85 μmol/L, vancomycin dosing of 1000 mg with an infusion length of two hours) simulated with the one-compartment models (left) and the two-compartment ...
[DOCX File]Word: Pediatric Intensive Care Unit: Continuous Infusion ...
https://info.5y1.org/continuous-infusion-vancomycin-dosing_1_c064d6.html
Vancomycin can also be given via 24-hour continuous infusion. Cefepime and ceftazidime can potentially be infused as 2 x12 hr infusions but are not stable enough for 24-hour infusion at …
[DOC File]ICU SEDATION GUIDELINES
https://info.5y1.org/continuous-infusion-vancomycin-dosing_1_303e02.html
Vancomycin. Loading dose 25mg/kg. ... LD 25mg/kg dosing based on total body weight (infusion over 30 minutes) was reported to result in insufficient peak serum concentrations in 25% of patients ... Alternative dosing strategies such as prolonged or continuous infusions have been suggested in critically ill patients in the setting of elevated ...
[DOC File]University of Strathclyde
https://info.5y1.org/continuous-infusion-vancomycin-dosing_1_b4d1a7.html
PEDIATRIC INTENSIVE CARE UNIT: CONTINUOUS INFUSION GUIDELINES FOR INFANTS AND CHILDREN . ... sodium bicarbonate, sodium nitroprusside, vancomycin ... and visual stimulation after dosing decreases the likelihood of these reactions. May see increased secretions. Glycopyrrolate may be effective in reversing some of the sialogogue effect.
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