Convert cefepime to oral

    • [PDF File]Cefepime - Hopkins Medicine

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      Cefepime is a fourth generation cephalosporin with activity against a wide range of Gram-negative bacteria including Enterobacteriaceae, Pseudomonas spp., and Acinetobacter spp. Cefepime is stable against Amp-C beta-lactamase-producing organisms (e.g., Enterobacter spp.). Its Gram-positive activity includes Streptococcus spp. and MSSA.


    • [PDF File]Medication Administration: Extended-Infusion Cefepime (Maxipime ...

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      Extended-Infusion Cefepime (Maxipime ... If IV access or medication timing is a problem, the pharmacist may convert the order to the equivalent intermittent dosingregimen without a physician’s order. 4. Maintenance to start based on order frequency a) E.g. cefepime 1gm x1 (over 30’), then 1g q8h (over 4 hours) starting 8 hours after bolus ...


    • [PDF File]Intravenous to Oral Conversion for Antimicrobials - Northern Health

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      Oral antimicrobials less potent than IV formulation. Step-down to a less potent oral agent requires individual patient assessment Parenteral Therapy Oral Therapy*** Oral Bioavailability Azithromycin 500 mg IV once daily x 3 days (5 days if suspected legionella) Azithromycin 500 mg PO x 1 then 250 mg PO once daily x 4 days Or


    • [PDF File]Converting from Intravenous to Oral Antibiotic Therapy - Remedi SeniorCare

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      automatically converting levofloxacin route from IV to oral. Am J Health-Syst Pharm. 2002; 59(22):2209-2215. 4. Mertz D, Koller M, Haller P, et al. Outcomes of early switching from intravenous to oral antibiotics on medical wards. J Antimicrob Chemother. 2009;64(1):188-199.


    • [PDF File]SKIN AND SOFT TISSUE INFECTIONS - Michigan Medicine

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      Cefepime* 2 g IV q8h + Clindamycin 900 mg IV q8h + Vancomycin* (see nomogram, AUC goal 400-600) another Anaphylaxis: Aztreonam* 2 g IV q8h administered). + Clindamycin 900 mg IV q8h + Vancomycin* (see nomogram, AUC goal 400-600) Optimal duration is unknown but should be continued for a minimum of 2-3 days after completion of surgical debridement


    • [PDF File]Table 13. Recommended Dosages for Oral and Parenteral Cephalosporins

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      Table 13. Recommended Dosages for Oral and Parenteral Cephalosporins Agent Route Adult Dose and Interval Pediatric Dose and Interval First-generation Cephalexin PO 0.25-1 g q6-12h 50-100 mg/kg/d, q6-8h Cefadroxil PO 0.5-1 g q12-24h 30 mg/kg/d, q12-24h Cephradine PO 0.5-1 g q6-12h 75-100 mg/kg/d, q6-12h


    • [PDF File]GUIDELINES FOR TREATMENT OF ODONTOGENIC INFECTIONS IN HOSPITALIZED ADULTS

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      + Cefepime 2 g IV q8h* + Metronidazole 500 mg IV/PO q8h Severe PCN or cephalosporin allergy (anaphylaxis, angioedema, hives): Vancomycin IV (see nomogram, AUC goal 400-600)* + Aztreonam 2 g IV q8h* + Metronidazole 500 mg IV/PO q8h For acute apical periodontitis and acute dentoalveolar abscess: • Duration is dependent on surgical debridement,


    • [PDF File]IV to PO Pharmacy Conversion Protocol - FormWeb

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      IV Agents Oral Agents IV Agents Oral Agents Fosphenytoin** 100 mg Q8 - 12h Phenytoin Same dose Same frequency Ampicillin 500 mg - 1g Q6 - 8h Q12h Q24h Amoxicillin 500 mg Q8h Q12h Q24h Phenytoin** 100 mg Q8 - 12h Phenytoin Same dose Same frequency ** Patient must be seizure free for 24 hours †Round to nearest tablet size; if oral dose is ...


    • [PDF File]Stanford De-escalation Guide for Gram-negative Bacteremia

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      line oral alternatives: Case by case basis. Consult ASP or ID if unsure. ... Otherwise call lab to add on cefepime testing. Ertapenem 1g IV q24h . Ciprofloxacin 500-750mg* PO BID : Levofloxacin 500-750mg* PO daily . TMP-SMX 8-10mg/kg/day PO divided in 2 or 3 doses if TMP/SMX MIC ≤ 20 (TMP MIC ≤1)


    • [PDF File]Severe Sepsis and Septic Shock Antibiotic Guide

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      • Cefepime 2g IV Q8H extended infusion • Aztreonam 2g IV Q8H Vancomycin Loading Dose + vancomycin 15mg/kg Pneumonia • Ceftriaxone 2g IV q24H plus Azithromycin 500mg IV q24h entry) + vancomycin 15mg/kg • Ceftriaxone 2g IV q24H plus Doxycycline 100mg IV Q12H • Levofloxacin 750mg IV q24h +/- Vancomycin Loading Dose (existing EPIC


    • [PDF File]Opioid PCA Conversion to Oral Opioid Regimen - Houston Methodist Hospital

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      2. Convert total IV opioid dose to oral opioid of choice 3. If converting from one opioid to another, reduce total daily dose by 20-50% to account for incomplete cross-tolerance 4. Divide total oral opioid dose by appropriate dosing frequency a. Immediate release formulations: q3-6h prn b. Extended release formulations: q8-12h scheduled i.


    • Intravenous to Oral (IV:PO) Anti-Infective Conversion Therapy

      to the oral route.However,the mean duration of IV ther apy before converting ranged from 2 to 8 days and was solely determined by clin-ical judgment in most cases.This makes interpretation of the contri-bution of oral therapy difficult. Better-defined trials have been recently conducted that facilitate the evaluation of oral conversion.Criteria ...


    • [PDF File]GUIDELINES FOR THE TREATMENT OF INTRA-ABDOMINAL INFECTIONS IN PATIENTS ...

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      cephalosporins other than cefepime, ceftriaxone, cefpodoxime, and cefotaxime can receive ceftriaxone or cefepime Oral step-down is appropriate for the following populations: Culture positive and clinically improving after 48-72 hours of IV therapy with oral antibiotic options feasible per culture and susceptibility results


    • [PDF File]SUPPORTING EVIDENCE FOR ALTERNATE CEFEPIME DOSING ... - Nebraska Medicine

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      Cefepime 2g q8hr Cefepime 1g q6hr Cefepime 2g q8hr for “Neutropenic Fever” Cefepime 2g q8hr* This includes all adults and children > 40 kg. Children weighing 40kg or less are excluded from the automatic dosage substitution. *Cefepime 2g q 8hrs is allowed only in neutropenic fever, and ordering clinicians must write the


    • [PDF File]Oral Cephalosporin Antibiotics: An Overview of Clinical ... - MDedge

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      21 days) has been reported to be an effective oral therapy alternative to doxycycline for adult patients presenting with early localized Lyme disease (ery-thema chronica migrans stage).8,21 Oral cefixime 400 mg, oral cefpodoxime proxetil 200 mg, and oral cefuroxime axetil 1000 mg may be used as single-dose therapy for uncomplicated gonorrhea.2,4,5


    • IV to Oral Switch Clinical Guideline for adult patients: Can ...

      Cefepime, gentamicin, meropenem , vancomycin Seek advice from Clinical Microbiology or Infectious Diseases The following IV drugs have equivalent oral doses: Azithromycin, Linezolid, Fluconazole, amethoxazole ^ Consider patient allergy status when converting to a penicillin. Possible to switch? (Prolonged therapy required for the


    • [PDF File]Antibiotic Therapy for Pseudomonas aeruginosa Bloodstream Infections ...

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      Pseudomonas aeruginosa; piperacillin-tazobactam; cefepime. Rising rates of antibiotic resistance, impacts on the intestinal microbiome, and antibiotic-associated adverse events [1] have ... longed-course groups transitioned to an oral fluoroquinolone during their treatment course, with the median day of transi-tion being 5 days for the short ...


    • [PDF File]HIGHLIGHTS OF PRESCRIBING INFORMATION Cefepime Injection in GALAXY ...

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      These highlights do not include all the information needed to use CEFEPIME Injection safely and effectively. See full prescribing information for CEFEPIME Injection. CEFEPIME injection, for intravenous use Initial U.S. Approval: 1996 -----INDICATIONS AND USAGE----- Cefepime Injection is a cephalosporin antibacterial indicated in the treatment ...


    • [PDF File]Antibiotics: IV to Oral - Safety and Quality

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      Lincomycin 600‐900mg IV TDS Clindamycin^ 300‐600mg oral TDS Fluconazole^ 200‐400mg IV daily Fluconazole^ 200‐400mg oral daily Metronidazole^ 500mg IV BD Metronidazole^ 400mg oral TDS *Usual dose for adult patients with normal renal function. ^Antimicrobials with excellent oral bioavailability


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