Dermatomyositis clinical trials

• [PDF File]CO Recent clinical trials in idiopathic inflammatory ...

  https://info.5y1.org/dermatomyositis-clinical-trials_1_39de32.html

  clinical trials, dermatomyositis, inclusion body myositis, inflammatory muscle diseases, treatment INTRODUCTION Idiopathic inflammatory myopathies (IIMs) are autoimmune multisystemic diseases. The major subsets of IIM studied in clinical trials are dermato-myositis, polymyositis, juvenile dermatomyositis (JDM) and sporadic inclusion body ...

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• [PDF File]Safety and Efficacy of Lenabasum in Refractory Skin ...

  https://info.5y1.org/dermatomyositis-clinical-trials_1_9b79d8.html

  Keywords: Amyopathic dermatomyositis , clinical trials , Cutaneous manifestations , dermatomyositis and patient outcomes SESSION INFORMATION Background /Purpose: Lenabasum is a synthetic, non-immunosuppressive, selective cannabinoid receptor type 2 agonist that activates resolution of innate immune responses.

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• [PDF File]Design Considerations for Clinical Trials Using the ...

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  Design Considerations for Clinical Trials Using the Cutaneous Dermatomyositis Disease Area and Severity Index as a Primary Endpoint Julie A. Brevard 1*, Mark Hurtt 1, Joanna Horobin , Olga Polyanskaya , James Baker 1, Victoria P. Werth2,3 and David F. Fiorentino4

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• [PDF File]Predictors of Clinical Improvement in Rituximab-Treated ...

  https://info.5y1.org/dermatomyositis-clinical-trials_1_2a3709.html

  clinical trials can be designed with stratification of patients with a good likelihood and those with a poor likelihood of improvement. The aim of this study was to identify the clinical and laboratory predictors of clinical improvement in patients with refractory myositis …

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• [PDF File]2016 ACR/EULAR Criteria for Minimal, Moderate and Major ...

  https://info.5y1.org/dermatomyositis-clinical-trials_1_6c6d9f.html

  Clinical Response for Adult Dermatomyositis and Polmyositis and Juvenile Dermatomyositis The ACR-EULAR Myositis Response Criteria Project Steering Committee Lisa Rider, ... adult and juvenile DM/PM clinical trials . PRELIMINARY . and therefore . ACR-EULAR PROJECT TO DEVELOP NEW RESPONSE CRITERIA FOR JDM AND ADULT DM/PM . 3 .

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• [PDF File]TITLE: Rituximab for Dermatomyositis: Clinical ...

  https://info.5y1.org/dermatomyositis-clinical-trials_1_e09699.html

  controlled trials, or controlled clinical trials were identified that evaluated the clinical effectiveness of rituximab for the treatment of adult patients with dermatomyositis. Six case series and four case reports described the use of rituximab in adults with dermatomyositis.

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• International Consensus Guidelines for Trials of Therapies ...

  ticenter international trials of therapies for adult and juvenile IIM. This report describes the current IMACS consensus guidelines for the design and conduct of clinical trials in adult and pediatric patients with myosi-tis. Given the limited number of controlled trials that …

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• Disease-specifi c quality indicators, outcome measures and ...

  Clinical Study (IMACS) Group (19, 20). Consensus was achieved by this group on a core set of outcome measures de-signed to assess three dimensions of myositis disease − disease activity, dis-ease damage, and health-related quality of life − for use in clinical trials (19). The myositis disease activity score is a

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• [PDF File]2016 American College of Rheumatology/European League ...

  https://info.5y1.org/dermatomyositis-clinical-trials_1_12898a.html

  Minimal, Moderate, and Major Clinical Response in Adult Dermatomyositis and Polymyositis An International Myositis Assessment and Clinical Studies Group/Paediatric Rheumatology International Trials Organisation Collaborative Initiative Rohit Aggarwal,1 Lisa G. Rider,2 Nicolino Ruperto,3 Nastaran Bayat,2 Brian Erman,4

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• [PDF File]Efficacy of IVIg Therapy in Inflammatory Myositis

  https://info.5y1.org/dermatomyositis-clinical-trials_1_12b59e.html

  Despite two randomized controlled trials report a variable and modest response in IBM [22, 23], IVIg may however be employed for lack of alternative therapies. In 9 children with refractory juvenile dermatomyositis, IVIg induced clinical improvement and allowed to reduce corticosteroids dose [24].

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