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[DOC File]STATIN-FIBRATE REPORT: Focus on Safety
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There was no significant difference between the two groups for major coronary events and the study did not show any significant difference in progression to end-stage renal disease among non-dialysis patients (3). ... myalgia and rhabdomyolysis. Renal impairment may be a pre-disposing factor for rhabdomyolysis and the manufacturer of ...
what is myopathy and rhabdomyolysis

myopathy and rhabdomyolysis symptoms | Answers from Doctors …
In a letter to the editor, pharmacists working with the FDA collected all cases of statin-associated fatal rhabdomyolysis that had been reported to the FDA before June 26, 2001.77 Cases were included if there was a clinical diagnosis of rhabdomyolysis, a temporal association between rhabdomyolysis and the use of a statin, and death was either ...
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[DOC File]UKMi Q&A xx - SPS
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Reports of myalgia and clinically significant increases in liver function tests (LFTs) were noted to be as high as 4% and 7.4%, respectively.1-7 Although the exact incidence is unknown, the most severe side effects of pitavastatin include hypersensitivity reactions and rhabdomyolysis; similar to other statins.
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[DOC File]Pharmacy Benefits Management Services Home
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Myalgia was assessed using a 100mm VAS. Primary outcomes were the number of patients taking simvastatin 40mg at 12 weeks, the number remaining on simvastatin therapy and the change in myalgia score. The study was powered (80%) to detect a 9-mm difference in the myalgia score between treatment groups.
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[DOCX File]Australian public assessment report for Ezetimibe ...
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Modest systemic reactions (e.g., myalgia, malaise, low-grade fever) are uncommon, and severe systemic reactions such as anaphylaxis, which precludes additional vaccination, are rare. The vaccine should be stored between 2-6 oC (refrigerator temperature, not frozen).
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[DOC File]Science Manuscript Template
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In the Musculoskeletal SOC, the most frequent serious ADRs were myalgia, rhabdomyolysis, muscle spasms, muscle weakness and extremity pain. The serious Gastrointestinal disorders were abdominal pain, nausea, pancreatitis, vomiting and upper abdominal pain with vomiting. ... simvastatin, pravastatin and atorvastatin, respectively. The difference ...
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UKMi Q&A xx - SPS
Once the depolarization was reversed, Sch-induced paralysis, rhabdomyolysis, hyperkalemia and cardiac arrhythmia would be alleviated simultaneously. Of note, CB[7] binds Sch with a similar binding affinity to that between WP[6] and Sch, however WP[6] exhibited much better antidotal efficacy than CB[7] in reversal of the Sch-induced mortality.
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Difference between myalgia and rhabdomyolysis