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[DOCX File]Australian Public Assessment Report for Lenvatinib mesilate
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Levothyroxine is used after initial thyroidectomy in patients to prevent hypothyroidism and to minimise potential thyroid stimulating hormone (TSH) stimulation of tumour growth. External beam radiation may be useful in patients with metastatic DTC that is refractory to radioiodine or in patients whose tumours do not concentrate radioiodine. Management of persistent or recurrent disease ...
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[DOC File]Pituitary Dwarf Skin Conditions
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There are a number of manufacturers producing these specialist medicated shampoos under license which in most countries are only available by prescription from a Vet. The shampoos are too numerous to mention and also the same product may have a different trade name in certain countries making them difficult to list. Malaseb for example uses chlorhexidine and miconazole as the active ...
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[DOC File]Digital Imaging and Communications in Medicine (DICOM)
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6.2.1 Multiple Value Sets Depending on Different Conditions 66 . 6.2.2 Target Content Items of Relationships 66. 6.2.3 ‘Include Template’ Macro 66. 6.2.4 Post-coordinated Codes and Has Concept Modifier Relationship 66. 7 DCMR Context Group Specifications 67. 7.1 Context group Table field definition 67. 7.2 Special Conventions for context group tables 67. 7.2.1 Include Context Group 67. 7.2 ...
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[DOCX File]FAISD Handbook March 2021
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In the event that submission of data for a new source of an active constituent reveals a significantly different toxicological profile from the reference active constituent, revised safety directions for products based on this new source may need to be developed. Label layout. The label layout requirements specified in the SUSMP shall also apply to first aid instructions, safety directions ...
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[DOC File]INDUSTRY OVERVIEW
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When the drug product is a racemate and the pharmacokinetic profiles of the isomers are different, manufacturers should monitor the enantiomers individually to determine such properties as dose linearity and the effects of altered metabolic or excretory function and drug-drug interactions. If the pharmacokinetic profile is the same for both isomers or a fixed ratio between the plasma levels of ...
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[DOCX File]U.S. Food and Drug Administration
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Because manufacturing processes and sources of raw materials differ among manufacturers, the interchangeability of extracts from different manufacturers cannot be assured. In general, a dose ...
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[DOCX File]The Tyranny of False Assumptions - Hormone Restoration
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hypothyroidism is central to medical practice, and, I will argue, the key to understanding the endocrine system as a whole. In particular, one must be able to diagnose and effectively treat hypothyroidism in order to understand cortisol deficiency (adrenal insufficiency).
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[DOCX File]Australian Public Assessment Report for Sodium zirconium ...
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The objectives of the study were to evaluate the safety and efficacy of three different doses of ZS administered daily for 28 days in maintaining normokalaemia (3.5 to 5.0 mmol/L) in subjects who had achieved normokalaemia following 2 days of acute therapy with ZS 10 g TDS. The dose in the chronic phase was randomised as 5, 10 or 15 g once daily. The dose was decreased to every second day if ...
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[DOC File]Soy Side Effects, Interactions and Warnings
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((Administration of levothyroxine concurrently with a soy protein dietary supplement results in decreased absorption of levothyroxine and the need for higher oral doses of levothyroxine to attain therapeutic serum thyroid hormone levels. - Endocr Pract 2001 May-Jun;7(3):193-4 -- Use of soy protein supplement and resultant need for increased dose of levothyroxine. -- Bell DS, Ovalle F ...
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[DOC File]PANDRH WG BE Criteria to require BE testing (in-vivo and ...
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Drug products are considered pharmaceutical alternatives if they contain the same therapeutic moiety, but are different salts, esters, or complexes of that moiety, or are different dosage forms or strengths (e.g., tetracycline hydrochloride, 250mg capsules vs. tetracycline phosphate complex, 250mg capsules; quinidine sulfate, 200mg tablets vs. quinidine sulfate, 200mg capsules). Data are ...
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Different manufacturers of levothyroxine