Direct vs indirect bilirubin
Difference Between Direct and Indirect Bilirubin
indirect bilirubin - bilirubin (insoluble) bound to albumin in circulating blood. Transported to liver for waste removal. direct bilirubin - bilirubin with glucose attached (soluble) Secreted by liver into the small intestine as part of bile . Bilirubin is converted to urobilinogen then stercobilin (brown pigment in feces) by bacteria of large intestine
[DOC File]Gastroenterology - Stanford University
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Elevated direct (or conjugated) bilirubin level Do urinalysis and urine culture. Evaluate for sepsis if indicated by history and physical. examination Jaundice present at or beyond age 3 wk, or sick infant. Total and direct (or conjugated) bilirubin. level If direct bilirubin elevated, evaluate for
CPQCC
7% higher by direct ISE. than by indirect ISE or FAES. What was previously observed in the field was a wide range of biases between direct ISE and FAES or indirect ISE results that varied depending on instrument-specific design features. These observations did not result from a flaw in the physiological model of electrolyte behavior.
[DOC File]Chapter 17: Blood
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Indirect hyperbilirubinemia, >85% of total bilirubin is unconjugated. Total bilirubin usually never >6 mg/dL in hemolysis. Check reticulocyte count and hemolysis labs . Direct hyperbilibinemia, >50% of total bilirubin is conjugated. Causes of indirect hyperbilirubinemia. Hemolysis. Ineffective erythropoiesis. Resorption of large hematoma ...
[DOC File]Estimation of Blood Glucose .ps
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• Bilirubin • Iron • Protein • Lipids ... Direct and indirect immunofluorescence, FPIA, RIA, Flow cytometry. V. Bacterial Serology: Non treponemal (VDRL, RPR) Treponemal (FTA-ABS), Streptozyme, Lyme Disease. To the satisfaction of the clinical instructor: Discuss the theory/principle of each test.
[DOC File]Josh Corwin
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REFERENCE VALUES Bilirubin Total Up to 1.10 mg/dL=18.81 µmol/L Bilirubin Direct Up to 0.25 mg/dL=4.27µ mol/L Questions: Write causes of jaundice. What are the commonest methods of estimating serum bilirubin in neonates? Mention the different causes of elevated direct and indirect bilirubins. Catalytic (Enzymatic) activities of Liver (ELFT)
Reference and Preferred Methods
Indirect bilirubin- glucuronosyltransferase- conjugated bilirubin. Conjugated, direct, soluble. Bile channels- ATP pump. Excreted via feces and urine. Overproduction of bilirubin. Impaired uptake or . Prehepatic increase heme production. Spherocytosis sickle …
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