Diseases that cause muscle degeneration

    • [PDF File]CLASSIFICATION OF PERIPHERAL NERVE DISEASES

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      AXONAL DEGENERATION CLASSIFICATION OF PERIPHERAL NERVE DISEASES Myelinopathy Acute inflammatory polyneuropathy (Guillain-Barré syndrome or GBS) Chronic inflammatory demyelinating polyneuropathy (CIDP) Charcot-Marie-Tooth, type 1 (CMT-1) Axonopathy Wallerian degeneration (trauma, vasculitis etc.) Distal axonopathies (dying back neuropathies)

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    • [PDF File]Facts About Metabolic Diseases of Muscle

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      5 Metabolic diseases of Muscle • 20 MdA progressive muscle weakness, rather than exercise intolerance, is the primary symp-tom. Over time, people with acid maltase deficiency or debrancher enzyme defi-ciency may eventually need a wheelchair to get around and, as respiratory muscles weaken, may require ventilatory assistance

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    • Large Polyglutamine Repeats Cause Muscle Degeneration in ...

      Large Polyglutamine Repeats Cause Muscle Degeneration in SCA17 Mice Shanshan Huang1,2,4, Su Yang1,4, Jifeng Guo1, Sen Yan1,3, Marta A. Gaertig1, Shihua Li1,*, and Xiao-Jiang Li1,3,* 1Department of Human Genetics, Emory University School of Medicine, 615 Michael Street, Room 355, Atlanta, GA 30322, USA 2Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of

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    • Large Polyglutamine Repeats Cause Muscle Degeneration in ...

      Mutant TBP in Muscle Causes Degeneration Gait abnormalities and muscle weakness are seen in some SCA17 patients (Koide et al., 1999; Rolfs et al., 2003). The distri-bution of mutant TBP in muscle cells led us to examine whether mutant TBP could cause muscle pathology. H&E staining of muscle tissues revealed normal morphology inthe skeletal mus-

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    • [PDF File]Diseases of Skeletal Muscle - Duke University

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      Dytrophic: replacement of normal muscle with fat and collage. muscle fibers split as they try to grow and replace whats been lost. nuclei move into center. loss of muscle. kids get calf pseudohypertrophy. Symptoms become more exaggerated as they get older. Can now live into their 20's due to improved respiratory care. Becker is milder than ...

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    • Ethanol Exposure Causes Muscle Degeneration in Zebrafish

      damage [24]. Thus, the primary cause of muscle degeneration in dystrophin-null sapje mutant zebrafish is sarcolemmal damage. In contrast, the primary cause of muscle damage in laminin a2 mutant zebrafish is failure of adhesion of muscle fibers to the MTJ. …

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    • [PDF File]Large Polyglutamine Repeats Cause Muscle Degeneration in ...

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      Cell Reports Article Large Polyglutamine Repeats Cause Muscle Degeneration in SCA17 Mice Shanshan Huang,1,2,4 Su Yang,1,4 Jifeng Guo,1 Sen Yan,1,3 Marta A. Gaertig,1 Shihua Li,1,* and Xiao-Jiang Li1,3,* 1Department of Human Genetics, Emory University School of Medicine, 615 Michael Street, Room 355, Atlanta, GA 30322, USA 2Department of Neurology, Tongji Hospital, Tongji Medical College ...

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    • Skeletal Muscle Degenerative Diseases and Strategies for ...

      PM08CH17-Wagers ARI 17 December 2012 8:58 Skeletal Muscle Degenerative Diseases and Strategies for Therapeutic Muscle Repair Mohammadsharif Tabebordbar,1 Eric T. Wang,2 and Amy J. Wagers1,3,∗ 1Department of Stem Cell and Regenerative Biology, Harvard University and Harvard Stem Cell Institute, Cambridge, Massachusetts 02138; email: tabebord@fas.harvard.edu,

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    • [PDF File]Inclusion Body Myositis: A Degenerative Muscle Disease ...

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      specific vacuolar degeneration and muscle fiber atrophy, conclud-ing with muscle fiber death. The mechanism of muscle fiber death in s-IBM is not well understood.There is compelling evidence that apoptosis does not participate in this process (46, 65, 72). Also, muscle fiber necrosis is very rare in s-IBM muscle biopsy. The

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    • Degenerative Lung Disease - Chest

      degenerative lung disease, showing residual lipiodol and extensive degeneration throughout both lung fields. The lateral view reveals marked increase in the postero-anterior diameter. This patient gave no clinical history of bronchospasm, merely progressive dyspnea. Three weeks after a …

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