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[DOC File]BISPNENOL A
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xiv. studies reporting no in vivo effects of low doses of bisphenol that used an insensitive rat, the charles river sprague-dawley (cd-sd) rat 194. xv. findings of no significant effects in experimental animals at doses of bisphenol a below 50 mg/kg/day or at ppb doses in aquatic animals (including studies with cd-sd rats) 201. xvi.

[DOC File]EN
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The eyes of the test animals should not be washed for at least 24 hours following instillation of the test substance, except for solids (see section 1.4.2.3.2), and in case of immediate corrosive or irritating effects. At 24 hours a washout may be used if considered appropriate.

[DOCX File]1439 Final Protocol
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Intravesical instillation of sodium hyaluronate (1.6%) and sodium chondroitin sulphate (2.0%) therapy (trade name iAluRil®) is indicated to re-establish the glycosaminoglycan layers (GAGs) of the urothelial vesical tissue in cases in which their loss can cause frequent and recurring problems such as painful bladder syndrome (PBS), interstitial cystitis (IC), treatment and prevent of recurrent ...

[DOC File]Interstitial Cystitis
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During a bladder instillation, also called a bladder wash or bath, the bladder is filled with a solution that is held for varying periods of time, averaging 10 to 15 minutes, before being emptied. The only drug approved by the U.S. Food and Drug Administration (FDA) for bladder instillation is dimethyl sulfoxide (DMSO, RIMSO-50).

[DOC File]A scoping study to identify hazard data needs for ...
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The effects of NP on bone marrow, spleen, liver, heart and placenta/foetus. Penetration and toxicity of different NP in the skin. The effects of ingested and inhaled NP on the normal functioning and immunological homeostasis of the gut. For NT, information is required regarding the following:

[DOC File]WHALE
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The so-called "side effects" of drugs are, in truth, unwanted direct effects. ... Bladder Fistula Wounds, Ulcers Varicosities ... Vitamin C, etc.. DMSO has only one side effect of which I am aware, i.e. all patients have a characteristic garlic-like odor from their body when receiving DMSO. ENZYME THERAPY.

[DOCX File]1439-FinalPSD-accessible
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Bladder instillation with HA-CS will be provided as an alternative to bladder instillation using DMSO, and to be utilised before more serious invasive interventions such as surgery or neuromodulation. In the case of DMSO, it is claimed that HA-CS is as effective (non-inferior comparative effectiveness) to DMSO with fewer side effects (superior ...

[DOC File]Defra, UK - Science Search
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The main metabolite of enrofloxacin, ciprofloxacin, has been widely used in human medicine for several years; side effects reported include gastrointestinal disturbances, some hypersensitivity reactions and crystalluria (EMEA, 1998c). 4.2 Repeat dose toxicity.

[DOC File]Engineered nanomaterials: A review of the toxicology and ...
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Intratracheal instillation of particulates at loading of more than about 100 – 200 µg per rat lung has the potential to cause effects associated with particulate overload of the lung. Exposing mice by nasopharyngeal aspiration provides better particle dispersion in the lower lung and is not as susceptible to lung overload issues as is ...

[DOC File]Emerging Intravesical Therapies for Non Muscle Invasive ...
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While high prevalence of local effects has hampered the use of doxorubicin, randomized trials have demonstrated that recurrence rates following treatment with epirubicin is inferior to BCG17, 18, which has limited its use to immediate post-operative instillation, BCG refractory disease, and carcinoma in situ.

[DOC File]Chapter 1
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Chapter 1 Introduction An overview of the anatomy and physiology of the bladder 1.1 Anatomy of the urinary bladder. Regions of the bladder. The urinary bladder is a hollow, muscular and distensible organ located posteriorly to the pubic symphysis bone in the pelvis when empty, but extends into the lower part of the abdominal space when filled.

Dmso bladder instillation side effects