Dopamine and drug addiction
[DOCX File]TwoCor - Home
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VTA, NAc dopamine transporter (DAT), etc. Psychoactive drugs / other neurotransmitter interactions. Summary of regions involved in addiction: the vicious cycle. Rate of progression from use to addiction. Depends on genetics (DAT in NAc) Depends on childhood abuse (corticosteroids?) Depends on specific drug (rate of rise of DA) All drugs push ...
Dopamine in Drug Abuse and Addiction: Results of Imaging Studie…
If dopamine is involved in cocaine-seeking behavior, we predict that dopamine levels will increase prior to the rat pressing the bar. And if dopamine is involved in cocaine-seeking behavior, then dopamine may hold the key to understanding the neurobiology of persistent drug addiction.
[DOCX File]Neurobiology of Addiction
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Di Chiara, G. A. (1998). Motivational learning hypothesis of the role of mesolimbic dopamine. in compulsive drug use. Journal of Psychopharmacology, 12 (l), 54-67. National Institute on Drug Abuse. (2012). Principles of drug addiction treatment: A research-based guide …
[DOC File]The relationship between dopamine and cocaine addiction
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: Drug tolerance results in people needing more and more of the same drug to get the same effect because, over time, drugs can cause the brain to produce less dopamine, the neurotransmitter that produces feelings of pleasure. Drug abusers may need more of the drug than before to reach the same level of dopamine to get the same “high.”
[DOC File]COGNITIVE SCIENCE 175
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These opposite proponent and opponent processes during the development of drug addiction may contribute to the intense drug craving experienced by addicts. Based largely on animal self-administration, the reinforcing effects of drugs have been linked to central dopamine activity in the mesolimbic dopamine system.
[DOC File]Quiz: The Brain and Addiction - National Institute on Drug ...
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So, because cocaine and amphetamines inhibit the reuptake of dopamine, they are stopping neurons from reabsorbing the used dopamine, so it stays present in the brain for longer periods of time. This extra dopamine causes one to experience heightened feelings of pleasure and addiction in wanting more of the drug.
[DOCX File]Overview - College of Humanities and Sciences - College of ...
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In the “new view” on dopamine reward and drug addiction, dopamine is still associated with reward and motivation but a new emphasis is also put on dopamine’s role in processing saliency. Drug addiction affects reward and saliency in the following ways: when a drug is first administered, there is a large amount of DA released by the ...
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