Dopaminergic drugs
4.9.1 Dopaminergic drugs used in Parkinson's disease
Drugs that stimulate dopaminergic release, like cocaine and amphetamine, or that are agonist of DA receptors promote waking and behavioral activation in mammals (Wise & Bozarth 1987, Di Chiara & Imperato 1988, Monti et al. 1990, Trampus et al. 1991, 1993, Nishino et al. 1998, Wisor et al. 2001).
Charla dopaminergic modulation of GHRH-GH axis
Previously, we suggested an involvement of D2-dopaminergic function in the expression of suicidal behavior by demonstrating a smaller growth hormone (GH) response to apomorphine, a dopaminergic agonist, in depressed patients with a history of suicide attempts in comparison to …
[DOCX File]CURRICULUM VITA
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The role of dopaminergic receptors in the control of GH release remains controversial. The dopamine receptor 2 (D2R) knockout mouse represents a useful model to study the participation of the D2R ...
[DOC File]Introduction - Bowling Green State University
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The effects of dopaminergic drugs and deep brain stimulation on speech in Parkinson’s disease. Poster presented at the annual convention of the Movement Disorders Society, Stockholm, Sweden. Darling White, M., Huber, J.E., and Barnes, D. (2014, February). Syntactic disambiguation in individuals with Parkinson’s disease.
[DOCX File]CURRICULUM VITA - Purdue University
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Stimulating PD drugs like selegiline, amantadine and modafanil may turn out to have a role. Impulsive Behaviours. A wide range of impulsive, repetitive and either purposeless or potentially harmful behaviours have been described in response to dopaminergic medication (both levodopa but especially dopamine agonist drugs).
[DOC File]PARKINSON’S DISEASE
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The single most useful measure is an otherwise unexplained drop in systolic blood pressure by ( 20 or 30 mmHg, depending on criteria used, in systolic BP three minutes after assuming the erect position.5 Unfortunately, dopaminergic drugs can cause OH, which makes results difficult to interpret.
[DOC File]Medical Management of Parkinson's Disease
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Dopaminergic receptors in the chemoreceptor trigger zone responsible for vomiting are accessible to dopaminergic antagonists which do not cross the blood-brain barrier. Drugs stimulating gastrointestinal motility are called prokinetic agents and are used specially in treating gastroesophageal reflux.
[DOC File]Medical Management of Parkinson's Disease
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The effects of dopaminergic drugs and deep brain stimulation on speech in Parkinson’s disease. Poster presented at the annual convention of the Movement Disorders Society, Stockholm, Sweden. Darling White, M., Huber, J.E., and Barnes, D. (2014, February). Syntactic disambiguation in individuals with Parkinson’s disease.
[DOC File]Reduced dopaminergic activity in depressed suicides
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Drugs that increase dopaminergic activity either aggravate existing schizophrenia or induce psychosis. Traditional antipsychotic drugs block D2 receptors in the CNS. Post-mortem studies show increase dopamine receptor density in brains of schizophrenics who were not treated with antipsychotics.
[DOC File]Pharmacology—Antipsychotic Drug Therapy
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Dopaminergic neurons are highly concentrated in certain areas of the brain, e.g., the limbic system and the basal ganglia. Drugs can affect the dopaminergic system by acting as direct stimulants of dopamine receptors (agonists), by inhibiting the breakdown of dopamine, or acting a a direct source of dopamine.
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