Drug metabolism chart
[DOC File]Pharmacokinetics and Pharmacodynamics
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During this “terminal phase” drug returns from the rapid and slow distribution volumes to the plasma, and is permanently removed from the plasma by metabolism or renal excretion. Equation 1 Curves which continuously decrease over time, with a continuously increasing slope (i.e., curves that look like figure 5), can be described by a sum of ...
[DOC File]National PBM Drug Monograph
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Metabolism through this system can also create drug interactions especially with potent inhibitors of CYP2D6 such as some antidepressants. The manufacturer recommends that newly diagnosed depression patients who require paroxetine or fluoxetine should half their current dose of tetrabenazine.
[DOC File]Pharmacology: Basics for RNs
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The final phase of drug metabolism is excretion. In the transport process, the drug or its metabolite is excreted via the kidney, feces, respiratory system, or by the skin [16]. Hydrophilic (water-soluble) compounds can be easily excreted. The routes include: Kidney. Bile. Saliva and sweat. Milk. Exhalation via the pulmonary system. Hepatic ...
[DOC File]UNIVERSITY OF SOUTHERN PHILIPPINES FOUNDATION
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IV. Course Description : This course deals with the Liberation, Absorption, Distribution, Metabolism, Elimination, Response, (LADMER) or the fate of . drug in living human or animal body. It monitors the movement of a drug in a living cell and the rate of eliminating through . the different organs of elimination. V. General Objectives of the ...
[DOCX File]Drug Information Common to the Class of Extended-Release ...
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High inter-patient variability in absorption, metabolism, and relative analgesic potency. Opioid detoxification or maintenance treatment shall only be provided in a federally certified opioid (addiction) treatment program (Code of Federal Regulations, Title 42, Sec 8). Specific Drug Interactions
Concept Map - Weebly
Allergies (Drug/Food/Environment): No known drug or food allergies noted in the chart. ... 2013). The patient has developed Xanthogranulomatous pyelonephritis and abnormal lipid metabolism is a possible etiologic factor for its development (Deem, 2012).
[DOC File]Equianalgesic Chart (Changes in italics)
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Drug Route Starting Dose (Adults > 50 Kg) Onset Peak Duration Metabolism Half Life Comments Codeine PO. IM. SQ 30 - 60 mg q 4 hr. 15 - 30 mg q 4 hr. 15 - 30 mg q 4 hr 30 min. 15 - 30 min. 30 - 60 min 1½ hr. 30 - 60 min. 2 - 4 hr 6 hr. 4 - 6 hr
[DOC File]RN Study Guide for Preparing for the NLN Medication ...
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Drug properties such as absorption, distribution, metabolism and excretion make up the pharmacokinetic profile of a drug. This affects the drug’s onset of action, peak concentration, duration of action, and bioavailability. Absorption - A drug must be absorbed into …
[DOC File]Drug - University of Washington
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SUMMARY: the “best” of azithro plus the “best” of clarithro rolled into one drug, with the added advantage of covering drug-resistant S. pneumoniae DOC for which diseases Indicated for CAP, AECB, sinusitis Absorption, distribution, metabolism, excretion A: oral 57% bioavailability, unaffected by food
[DOC File]DRUG ABSORPTION, DISTRIBUTION AND ELIMINATION ...
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Since the liver is a major site of drug metabolism, this first-pass effect may reduce the amount of drug reaching the target tissue. In some cases, the first-pass effect results in metabolic activation of an inert pro-drug. 3. Gastric emptying times vary among patients and contribute significantly to intersubject variability in drug absorption.
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