Drugs that block dopamine
[DOC File]Pharmacology—Antipsychotic Drug Therapy
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Dopamine Hypothesis. The dopamine hypothesis . suggests that excessive dopaminergic activity underlies schizophrenia includes the following: Drugs that increase dopaminergic activity either aggravate existing schizophrenia or induce psychosis. Traditional antipsychotic drugs block D2 receptors in the CNS.
[DOC File]Schizophrenia
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Anti-psychotic drugs block dopamine receptors very quickly, yet it can take days to change the behaviour of people with schizophrenia. Barlow and Durand (1995) believe that neuroleptic drugs block dopamine fairly rapidly, but generally fail to reduce the symptoms of schizophrenia for …
[DOC File]STRENGTHS AND WEAKNESS OF THE DOPAMINE HYPOTHESIS
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Drugs such as L-Dopa give psychotic symptoms Some genes are link to dopamine production Brain differences in the front and temporal lobes seem to be different for schizophrenics. PET scans have shown that drugs that block dopamine don’t always reduce the symptoms Anti-schizophrenic drugs take a few days to work
[DOC File]Psychoactive Drugs
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An example is Ecstasy. Ecstasy is also known as MDMA, and like all designer drugs, is both a stimulant (derived from amphetamines) and a hallucinogen. It triggers the release of dopamine, but its main effect is to release stored serotonin and block its reabsorption.
[DOC File]Neurotransmitter Notes:
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Drugs like cocaine, opium, heroin, and alcohol increase the levels of dopamine, as does nicotine. If it feels good, dopamine neurons are probably involved! The severe mental illness . schizophrenia. has been shown to involve excessive amounts of dopamine in the frontal lobes, and drugs that block dopamine are used to help schizophrenics.
[DOC File]Drugs for GI Tract Disorders - Josh Corwin
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Phenothiazines (PTZ) primarily block dopamine (D2) receptors at the CTZ, thereby decreasing stimulation of the vomiting center. Also block D2 receptor in the solitary tract nucleus. As a class, PTZ have anti-emetic, anti-psychotic, anticholinergic, antihistamine, and sedative properties.
[DOC File]THORAZINE MEDICATION SHEET
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Drug classes . Phenothiazine. Dopaminergic blocking agent. Antipsychotic. Antiemetic. Antianxiety agent. Therapeutic actions . Mechanism not fully understood; antipsychotic drugs block postsynaptic dopamine receptors in the brain; depress those parts of the brain involved with wakefulness and emesis; anticholinergic, antihistaminic (H 1), and alpha-adrenergic blocking.
[DOC File]Best Student Essay: Chloe Parkinson
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Finally, although it is widely accepted that the majority of anti-psychotic drugs block dopamine receptors, to infer from this that dopamine hyper-activity is the major cause of schizophrenia is to oversimplify. It is now clear that the neurotransmitter systems interact and that the mapping of these cortical pathways is only just being explored.
[DOC File]TOXICOLOGY – TEST 1 STUDY GUIDE
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These drugs block dopamine in the brain and periphery. Efficacy or usage correlates w/ ability to block dopamine receptors in the limbic system. Include thioridazine, chlorpromazine, and haloperidol.
[DOC File]Drug Therapy & Research
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Dopamine Agonists . These drugs act like dopamine in that they send the same message to nerve cells. They are less likely to result in dyskinesias, because dyskinesias are actually caused by too much dopamine. Researchers believe they may have a neuroprotective effect. bromocriptine (Parlodel) [usually given with L-dopa] pramipexole (Mirapex)
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