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What is a normal CK level?
Serum CK is “gold standard” for diagnosis and monitoring of ER; serum myoglobin is best used for risk prediction CK >5X ULN is a low threshold designed for high sensitivity, however it has low specificity. Normal baseline and post-exercise CK levels vary by age, gender, race, type of exercise, etc.

What is a mild elevation of CK?
Mild elevations of CK encompass a wide differential diagnosis and require careful consideration of the need for further investigation. Myoglobinuria- Myoglobin gives a positive reaction with conventional urine dipstick testing for haem containing components.

Does a high CK elevation increase the risk of metabolic acidosis?
There is no agreed simple answer to this question but patients with CK elevations greater than 30 X the top of normal (i.e. greater than about 5000 IU/L) probably have an increased risk as do those with a significant metabolic acidosis (bicarbonate

How should CK levels be managed in an inpatient setting?
Manage as per Algorithm II: Patients with CK levels >20,000 U/L or any significant high risk markers, may require further testing and observation17,30,31,34 in an inpatient setting. Accordingly, higher level of care should be considered and the patient should be managed as per Algorithm II. Appendix 1.

[PDF File]Muscle Edema -Recognizing Patterns and Associated Causes
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• Elevated creatinine kinase (CK) levels • Signal intensity correlates with serum CK levels Delayed Onset Muscle Soreness A-C: Note extensive muscle edema (*) in patient who presented with severe pain and elevated CK levels 3 days after a 2 hour strenuous upper body work out A: Ax STIR * * * B: Ax T2 FS * * C: Sag T2 FS * *

[PDF File]Clinical Practice Guideline for the Management of ER
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physiologic muscle breakdown (ICD-10: M62.9 D–isorder of muscle , unspecified), exertional rhabdomyolysis ( ICD-10: M62.82 – Rhabdomyolysis), or other causes for cola -colored urine such as exercise-induced hemolysis. Additional ICD-10 Y cause“ ” coding can be considered as

[PDF File]BLOOD SCIENCES DEPARTMENT OF CLINICAL BIOCHEMISTRY
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Mild to moderate CK elevations . Mild to moderate elevations of CK upto levels of 5000mIU/L have a wide variety of causes. Patients may or may not be symptomatic at this level. Common causes of mild to moderate elevations of CK include: Ethnicity CK values are typically slightly higher in non-caucasian individuals Muscle trauma/overuse Recent ...

[PDF File]Asymptomatic or Minimally Symptomatic HyperCKemia ...
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older than 40. Serum CK levels in at least three separate mea-surements after rest ranged between 265 and 8000 U/L. Twenty-one patients had serum CK levels > 1000 U/L and 19 had CK < 1000 U/L. Four subjects (10%) had familial hyperCKemia without evidence of a neuromuscular disorder. Nineteen individuals (48%) were completely asymptomatic, 20

[PDF File]Approach to asymptomatic creatine kinase elevation
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Patients who still have elevated CK after taking into account the 97.5% threshold, re-peat testing after a week of rest, and a level more than 1.5 times the upper limit of normal for sex and race should first be evaluated for the many nonneuromuscular conditions that can cause elevated CK (Table 1).7–9 Cardiac causes should be evaluated by his-

[PDF File]CKemia. Neurology International Open 2018; 00: 00–00 ...
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hyperCKemia, with CK values > 1000 U/l (16,7 µkat/l) being indicative of a primary muscle disorder. Diseases with very high CK values include subtypes of muscular dystrophies, idiopath - ic inflammatory myopathies and metabolic myopathies. How-ever, a normal or only slightly elevated CK value does not ex - clude the presence of a myopathy.

Elevated ck icd 10