Eliquis 10 mg bid

    • ELIQUIS 5 MG FILM-COATED TABLETS Table of Content …

      https://labeling.pfizer.com/ShowLabeling.aspx?id=12117%20

      The recommended dose of apixaban is 5 mg taken orally twice daily. Dose reduction The recommended dose of apixaban is 2.5 mg taken orally twice daily in patients with NVAF and at least two of the following characteristics: age ≥80 years, body weight ≤60 kg, or serum creatinine ≥1.5 mg/dL (133 micromole/L).

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    • [PDF File] Anticoagulation in Venous Thromboembolism - Squarespace

      https://static1.squarespace.com/static/53c1a2cce4b0e88e61f99b70/t/5a862817652dea5036d77690/1518741528086/VTE.pdf

      (Eliquis®) 10 mg BID X 7 days then 5 mg BID Reduce dose by 50% if co-administered with strong dual inhibitors of cyto-chrome CYP3A4P and P-gp (eg. ketoconazole and clarithromycin) Avoid use with strong dual inducers of CYP3A4 and P-gp (eg. rifampin) Not recommended in patients with prosthetic heart valves

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    • [PDF File] ELIQUIS DOSAGE BY LEVEL OF RENAL IMPAIRMENT IN …

      https://www.cpd-umanitoba.com/wp-content/uploads/EN-ELI-Dosing.pdf

      Dosing schedule. Continued prevention of recurrent DVT or PE 2.5 mg BID§. Prevention of VTE in: 2.5 mg BIDfor 10 to 14 days. 2.5 mg BIDfor 32 to 38 days – elective knee replacement surgery – elective hip replacement surgery Initial dose should be given 12 to 24 hours after surgery, once hemostasis established.

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    • [PDF File] Oral Anticoagulant Comparison Chart - Remedi SeniorCare

      https://www.remedirx.com/wp-content/uploads/2015/10/2015-04-MR-Anticoagulant-Comp-Chart.pdf

      Drug 1Enoxaparin (Lovenox®) Warfarin2 Rivaroxaban (Xarelto®)3 Dabigatran (Pradaxa®)4 Apixaban (Eliquis®)5 Indications *Prophylaxis of DVT *Treatment of DVT *Prophylaxis of Ischemic Complications of UA and ... 10 mg daily for 12-14 days . Hip: 10 mg daily for 35 days 150 mg twice daily 5 mg twice daily : In patients with 2 of the following ...

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    • Dosing Guide - ELIQUIS

      https://www.eliquis.com/eliquis/servlet/servlet.FileDownload?file=00P1Y000011vwqtUAA

      10 mg twice daily for the first 7 days After 7 days, transition to 5 mg twice daily 2.5 mg twice daily after at least 6 months of treatment for DVT or PE 2.5 mg twice daily for 35 days starting 12 to 24 hours after hip replacement surgery 2.5 mg twice daily for 12 days starting 12 to 24 hours after knee replacement surgery Prophylaxis of DVT,

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    • [PDF File] label - Food and Drug Administration

      https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/202155s021lbl.pdf

      The recommended dose of ELIQUIS is 10 mg taken orally twice daily for the first 7 days of therapy. After 7 days, the recommended dose is 5 mg taken orally twice daily. Reduction in the Risk of Recurrence of DVT and PE . The recommended dose of ELIQUIS is 2.5 mg taken orally twice daily after at least 6 months of treatment for DVT or PE

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    • [PDF File] Xarelto Dosing Guide

      https://www.xarelto.com/sites/g/files/vrxlpx171/files/2020-01/dosing-guide-xarelto-effective-protection-indications-worldwide-09-2018.pdf

      4 Mode of Action 1,3 aChange from baseline (ng/ml enoxaparin).bEnoxaparin 40 mg. cXarelto 10 mg. Xarelto® is a fast-acting, oral, direct factor Xa inhibitor that provides protection for your patients, with simple dosing1 Fast onset of action3 Xarelto works as fast as enoxaparin, with no injections required3 Graph adapted from Kubitza D., et al. 2013.3 ...

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    • [PDF File] ELIQUIS (apixaban) Prescriber Guide

      https://www.sfda.gov.sa/sites/default/files/2021-02/ELIQUIS%C2%AE%20%28apixaban%29%20Prescriber%20Guid.pdf

      should also receive ELIQUIS ® 2.5 mg bid (Figure 2). MORNING NIGHT ... for the treatment of acute DVT and treatment of PE is 10 mg taken orally bid for the first 7 days followed by 5 mg taken orally bid with water, with or without food. As per available medical guidelines, short duration of treatment (at least 3 months) should be based ...

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    • Dosing Guide - ELIQUIS

      https://www.eliquis.com/eliquis/servlet/servlet.FileDownload?file=00P4z00001PhAaDEAV

      Please see attached Full U.S. Prescribing Information, including. Boxed WARNINGS, and Medication Guide. 10 mg twice daily for the first 7 days After 7 days, transition to 5 mg twice daily 2.5 mg twice daily after at least 6 months of treatment for DVT or PE 2.5 mg twice daily for. 35 daysstarting 12 to 24 hours after hip replacementsurgery 2.5 ...

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    • [PDF File] Is Apixaban (Eliquis®) an Option for Your Patient - RxFiles

      https://www.rxfiles.ca/rxfiles/uploads/documents/CLOT-Apixiban-Checklist-Final-CPP.pdf

      10 mg bid for 7 days, followed by 5 mg bid CrCl Less than 30 mL/min: After at least 6 months of treatment, recommended dose for continued prevention of recurrent DVT/PE is 2.5mg BID caution as higher bleeding risk. -29 mL/min Usual dose, but use Hip & Knee Replacement 2.5 mg bid x 10 -14 days (TKR); x 32 38 days (THR) < 15 mL/min: Avoid Use

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    • [PDF File] Direct oral anticoagulants for superficial-vein thrombosis

      https://www.thelancet.com/pdfs/journals/lanhae/PIIS2352-3026(17)30013-3.pdf

      To address some of these unmet clinical needs, the SURPRISE study compared the direct oral anticoagulant rivaroxaban with 2·5 mg fondaparinux daily for the treatment of superficial vein thrombosis.10 Rivaroxaban was given at the prophylactic dose of 10 mg once a day and all patients received 45 days of treatment and were followed-up at 3 ...

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    • [PDF File] PRODUCT MONOGRAPH - Bristol Myers Squibb

      https://www.bms.com/assets/bms/ca/documents/productmonograph/ELIQUIS_EN_PM.pdf

      In high-risk patients following acute coronary thrombosis, apixaban 5 mg bid, as an adjunct to standard anti-platelet treatment, has led to significantly increased bleeding (see ACTION AND CLINICAL PHARMACOLOGY, Post- ... ELIQUIS 5 mg twice daily or 2.5 mg twice daily provides adequate anticoagulation in patients with prosthetic heart valves ...

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    • [PDF File] DEEP VEIN THROMBOSIS (DVT): TREATMENT

      https://thrombosiscanada.ca/wp-uploads/uploads/2021/11/3.-Deep-Vein-Thrombosis-Treatment_14November2021.pdf

      with a CrCl <25 mL/min. Apixaban is dosed at 10 mg PO twice daily for the first 7 days, followed by 5 mg PO twice daily for the duration of treatment. For patients continuing on long-term treatment be-yond 6 months, consideration can be given to reducing the dose to 2.5 mg PO BID.

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    • [PDF File] DOAC DO’S and DON’T’S - OHSU

      https://www.ohsu.edu/sites/default/files/2020-03/CPD%20IM20-Thu-05-DeLoughery.pdf

      R 15 mg bid x 21 days A 2.5 mg BID R 10 mg qD A 5.0 mg BID x 6-12 M R 20 mg qD x 6-12 M Acute 6-12 Months > 6-12 Months. Direct Oral Anticoagulants

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    • [PDF File] ELIQUIS DOSAGE BY LEVEL OF RENAL IMPAIRMENT IN …

      https://www.cpd-umanitoba.com/wp-content/uploads/2021/05/EN-ELI-Dosing.pdf

      of recurrent DVT or PE 2.5 mg BID§ Prevention of VTE in: 2.5 mg BID for 10 to 14 days 2.5 mg BID for 32 to 38 days – elective knee replacement surgery – elective hip replacement surgery Initial dose should be given 12 to 24 hours after surgery, once hemostasis established. Prevention of stroke and systemic embolism in AF (2.5 mg BID in

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    • [PDF File] ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS

      https://www.ema.europa.eu/en/documents/product-information/eliquis-epar-product-information_en.pdf

      If cardioversion is required before 5 doses of apixaban can be administered, a 10 mg loading dose should be given, followed by 5 mg twice daily. The dosing regimen should be reduced to a 5 mg loading dose followed by 2.5 mg twice daily if the patient meets the criteria for dose reduction (see above sections Dose reduction and Renal impairment ...

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    • Dosing Guide - ELIQUIS

      https://www.eliquis.com/eliquis/servlet/servlet.FileDownload?file=00P4z00001PhAa3EAF

      5 mg twice daily in most patients Dose adjustment for NVAF patients: 2.5 mg twice daily is recommended for patients with at least 2 of the following characteristics: • age ≥80 years • body weight ≤60 kg • serum creatinine ≥1.5 mg/dL 10 mg twice daily for the first 7 days CONTRAINDICATIONS • Active pathological bleeding

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    • [PDF File] Apixaban - Thrombosis Canada

      https://thrombosiscanada.ca/wp-uploads/uploads/2021/12/20.-Apixaban-Eliquis_02December2021-1.pdf

      APIXABAN (ELIQUIS®) OBJECTIVE: To provide an overview of the mechanism of action, licensed indications, dosing regimens, and ... 10 mg BID for 7 days, followed by 5 mg BID. No dose adjustment is necessary in patients with mild or moderate renal impairment (CrCl ≥30 mL/min). There are limited clinical data in patients with severe renal ...

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    • [PDF File] Anticoagulation Indications for therapeutic anticoagulation

      https://cpd.partners.org/sites/default/files/Anticoagulation_guidelines%5B1%5D.pdf

      Eliquis (Apixaban) +/- 10 mg BID loading dose x 7 days then 5mg BID. Renal dosing for afib indication 2.5mg ID with at least 2/3 criteria of age ≥ 80, Scr ≥ 1.5, or weight ≤ 60 kg. There is no FDA-approved renal dosing for VTE, patients with Scr ≥ 2.5 or a rl ≤ 25 mL/min were excluded from trials. Xarelto (Rivaroxaban) +/-

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    • [PDF File] DOAC Dosing for Atrial Fibrillation (AFib) - American College …

      https://www.acc.org/~/media/Non-Clinical/Images/Tools%20and%20Practice%20Support/Information-Graphics/2018/10/DOAC-Dosing-for-Atrial-Fibrillation-AFib-UPDATED-Feb-19-19.pdf

      Usual Dose 5mg BID 150mg BID 60mg daily (CI if CrCl ≥95 mL/min)* 20mg daily with food Reduced Dose 2.5mg BID 75mg BID 30mg daily 15mg daily with food Indications for Reduction 1. If 2 of 3 factors present: Age ≥80 years SCr ≥1.5 mg/dL Weight ≤60 kg 2. Coadministered with combined P-gp and strong CYP3A4 inhibitors (e.g., …

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    • [PDF File] HIGHLIGHTS OF PRESCRIBING INFORMATION The …

      https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/202155s032lbl.pdf

      serum creatinine greater than or equal to 1.5 mg/dL, the recommended dose is 2.5 mg orally twice daily. (2.1) • Prophylaxis of DVT following hip or knee replacement surgery: • The recommended dose is 2.5 mg orally twice daily. (2.1) • Treatment of DVT and PE: • The recommended dose is 10 mg taken orally twice daily for 7 days,

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    • Dosing Guide - ELIQUIS

      https://www.eliquis.com/eliquis/servlet/servlet.FileDownload?file=00P1Y000011vwqZUAQ

      5 mg twice daily in most patients Dose adjustment for NVAF patients: 2.5 mg twice daily is recommended for patients with at least 2 of the following characteristics: • age ≥80 years • body weight ≤60 kg • serum creatinine ≥1.5 mg/dL 10 mg twice daily for the first 7 days CONTRAINDICATIONS • Active pathological bleeding

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    • [PDF File] Direct Oral Anticoagulants: Factor IIa and Xa Inhibitors

      https://pharmacy.uconn.edu/wp-content/uploads/sites/2740/2021/09/HO-6-per-page-DOAC.pdf

      20 mg PO daily with the Treatment evening meal 10 mg PO daily without regards high to meals 15mg PO BID for 21 days followed by 20mg PO daily 2.5 mg PO BID in combo daily low‐ dose aspirin 2.5mg PO BID in combo with daily low‐dose aspirin CrCl 15‐50 mL/min 15 mg PO daily with the evening meal

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    • [PDF File] ELIQUIS (Apixaban) Leitfaden für medizinische Fachkreise

      https://www.bms.com/assets/bms/de/documents/2021%20Eliquis%20HCP%20Guide%20AT%20v11.pdf

      ELIQUIS® 5 mg ELIQUIS® 5 mg Abb. 1 Kriterien für ELIQUIS® 2,5 mg, 2 x tägliche Dosierung Körpergewicht ≤ 60 kg Alter ≥ 80 Jahre mindestens 2 Kriterien oder Schwere Nierenfunktionsstörung (CrCl 15 – 29 ml/min) ELIQUIS® 2,5 mg, 2x täglich ELIQUIS® 2,5 mg, 2x täglich Abb. 2 Tablette nicht in Originalgröße dargestellt

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    • [PDF File] VTE Prophylaxis - Rush University

      https://www.rushu.rush.edu/sites/default/files/_Rush%20PDFs%20and%20Files/IPCE/Updated%20Adult%20COVID-19%20Anticoagulation%20Treatment%20Guidelines.pdf

      Rivaroxaban 15 mg bid x 21 days followed by 20 mg daily thereafter OR apixaban 10 mg bid x 7 days followed by 5 mg bid thereafter In patients who do not have insurance coverage for a DOAC or in whom a DOAC may be contraindicated, treatment doses of enoxaparin may be continued for the time frame listed above

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