Endogenous pathway lipid metabolism
[DOC File]440 LN Part 1
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Metabolism and Biotransformation of Pesticides. Biotransformation refers to alteration of a chemical by a biological system. It includes microbial action, but excludes (for example) photodegradation. Metabolism is often used as a synonym for biotransformation, but this is not strictly accurate. Metabolism is a somewhat narrower term.
Fat Metabolism: Fat Digestion, Absorption & Assimilation
In addition, they act as ligands for interaction with lipoprotein receptors in tissues such as apo B-100 and apo E for the LDL receptor, apo E for the remnant receptor, and apo A-I for the HDL receptor.12 The liver plays a vital role in lipid metabolism. The endogenous lipids produced by the liver account for about 1.5 g of lipids daily and ...
[DOC File]Lipids, lipoproteins, apolipoproteins and their disease ...
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For instance, ApoAII and ApoB48 as structural elements, while ApoB100 and ApoE as ligands, ApoAI and ApoCII as enzyme activators. The way, which leads to LDL synthesis, is an endogenous pathway. It also exist an exogenous pathway, which can implicate into endogenous pathway and interferes with the LDL metabolism (Silbernagl, 2009).
[DOCX File]C O N T E N T
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Interstrain Differences in the Severity of Liver Injury Induced by a Choline- and Folate-Deficient Diet in Mice are Associated with Dysregulation of Genes Involved in Lipid Metabolism.
[DOC File]The role of Wnt signaling pathway in tumor metabolic ...
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Lipid Metabolism: TAG synthesis from glucose, fructose, and certain a.a.s. (esp. low-fat diet/high intakes of CHO/proteins). b. Endogenous synthesis of TAG: Excess f. as. in. relation to protein will lead to fatty liver. Fatty acid synthesis. Cholesterol synthesis and excretion. Lipoprotein metabolism: assessed by serum lipid and lipoprotein ...
[DOC File]STATIN-FIBRATE REPORT: Focus on Safety
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Transfer of -ketols (pentose phosphate pathway) -- 10% of carbohydrate metabolized . this way. This pathway provides pentoses for RNA and DNA synthesis and NADPH . for the biosynthesis of fatty acids and other endogenous reactions. c. Non-coenzyme function – TTP involved in the control of chloride channels in brain
[DOCX File]Lipid metabolism - Imperial College London
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In recent years, it has been found that the metabolic reprogramming of tumor cells also includes pentose phosphate bypass, lipid and protein and anabolism associated with nucleic acid synthesis, and a large number of endogenous oxygen free radicals, which are involved in the development of tumors has played an important role [15-18].
[DOC File]Chapter 11 - Introduction to Metabolism
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Changes to skeletal muscle expression of enzymes integral to lipid metabolism tend to support these changes in lipid uptake, oxidation and storage. The expression of lipoprotein lipase, an enzyme that hydrolyses circulating triglycerides to provide free fatty acids to cells, has been reported to increase in rodents and rabbits following SCFA ...
[DOC File]Biochemistry of Specialized Tissues
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Klosiewicz-Latoszek, Szostak WB. Comparative Studies on The Influence of Different Fibrates on Serum Lipoproteins in Endogenous Hyperlipoproteinemia. Eur J Clin Pharmacol 1991;40:33-41. Gaist D, Garcia-Rodriquez LA, Huerta C, et al. Lipid-Lowering Drugs and Risk of Myopathy: A Population-Based Follow-Up Study. Epidemiology 2001;12:565-569.
Bio-Sketches of
lipid digestion - triacylglycerols hydrolyzed to fatty acids by phospholipases. absorption occurs in intestine ---> blood ---> body. can also have endogenous sources, such as glycogen and triacylglycerols. catabolism yields 3 possible compounds: 1) acetyl CoA. 2) …
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