Ertapenem spectrum of coverage
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Introduction: serious infections on soft tissue wounds especially induce, apart from sepsis, problems of coverage and healing. They therefore require care and prolonged antibiotic therapy, as well as staff mobilization for bandage. That is why in this context, we proposed as alternative to conventional therapy to develop the technique of ...
[DOC File]Antimicrobial Pharmacotherapy in Children
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Ertapenem’s antimicrobial spectrum more closely resembles that of ampicillin-sulbactam (see section below on (-lactamase and antimicrobial resistance) than that of the other carbapenems. Major side effect of concern: seizures. Risk appears lowest with meropenem and it …
[DOCX File]ICU SEDATION GUIDELINES
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In patients with penicillin allergies, ertapenem (Invanz) is used as an alternative. While empiric monotherapy with either of these agents is acceptable, coverage for MRSA with an agent such as vancomycin is advisable as methicillin resistance is now found …
Investor Overview | Endo International plc
Ertapenem for injection. 17,874. 32,219. ... Amounts recovered under our insurance policies could be materially less than stated coverage limits and may not be adequate to cover damages, other relief and/or costs relating to claims. In addition, there is no guarantee that insurers will pay claims or that coverage will otherwise be available. ...
[DOC File]General Outline for Antibiotics (a good study guide)
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A. spectrum of coverage . 1. broad (both G+ and G-, but some fluoroquinolones have better coverage against G+ than others) 2. works well against intracellular pathogens. 3. newer fluoroquinolones work against anaerobes. B. mechanism of action. 1. targets are DNA gyrase (for G-) …
[DOCX File]Northwestern Medicine Antimicrobial Stewardship
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Going home on ertapenem and require a one-time dose prior to discharge to verify tolerance With documented ESBL infection in which Pseudomonal coverage is not required; this indication requires approval by the Antimicrobial Stewardship Team or an ID physician
[DOC File]Drug
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Spectrum (Gm+, Gm-, anaerobes) Very good coverage of almost all Gram negatives; borderline for Pseudomonas. Decent Streptococcus coverage and non-resistant S. …
[DOC File]PHARMACOLOGY BASIC PRINCIPLES
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QT interval: (++++) (but low incidence of torsade de pointes due to broad spectrum of activity) Bretylium: interferes with neuronal release of NE; lengthen ventricular but not atrial AP, effect most pronounced in ischaemic cells; has +ive inotropic action when first administered due to release of NE.
Case Notes for:
The use of empiric broad-spectrum antimicrobial coverage is recommended to cover aerobic organisms, facultative Enterbacteriacae and anaerobic organisms, such as B. fragilis. The Infectious Disease Society of America and the American Surgical Infection Society supports the use of targeted emperic therapy for the treatment of intra-abdominal ...
Investors | Tetraphase
Due to gaps in the spectrum of coverage of antibiotics, ... In December 2014, we announced that Xerava met the primary endpoint of statistical non-inferiority compared to ertapenem in IGNITE1 for the treatment of cIAI. In July 2017, we announced that Xerava met the primary endpoint of statistical non-inferiority compared to meropenem in IGNITE4 ...
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