Examples of live attenuated vaccines
Scott Winston and I had a somewhat lengthy discussion ...
A live attenuated MV vaccine (LAV), introduced in 1963, is widely used, safe, and provides long-term protection from measles. LAV was derived from Enders and Peebles’ original measles virus (MV) isolate (7) and attenuated by passage in chick cells (8).
[DOC File]comenius.susqu.edu
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Virology Class 6 – Fall, 2014. Virus Vaccines and Antiviral Agents. I. Virus Vaccines. A. Overview. B. Live, Attenuated Vaccines. i. General Considerations
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Live attenuated vaccines may revert to the wild type and cause pathology. ... Examples include, MDP (muramyl dipeptide), lipid A (purer form of LPS). C3d component of complement (stimulates innate response) Unmethylated non-mammalian DNA is a potent adjuvant (see later on DNA vaccines). Stimulates innate immune response as it is a type of PAMP ...
[DOC File]Alan Hinman
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However, live attenuated vaccines might be affected by circulating antibody to the antigen. And as I’ve mentioned, the antibody in these products are not only specific to one disease but it can be multiple diseases, it may be the disease that you’re trying to prevent with the vaccination.
[DOC File]Centers for Disease Control and Prevention’s
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Examples of off label use might include use of a product in an age group outside the recommended age group or use in a population for whom the vaccine is contraindicated. For example, administering live, attenuated influenza vaccine (LAIV) to a person with asthma would be an off-label use.
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been actively investigating the return of H1N1 in 1977, and based on that work we are convinced it leaked out of a Russian lab that was working on a live-attenuated H1N1 virus vaccine.
[DOC File]Vaccine
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Live, attenuated vaccines induce an immunologic response more similar to that resulting from natural infection than do killed vaccines. The live, attenuated viruses are believed to confer lifelong protection with one dose in those who respond. Killed vaccines do not induce permanent immunity with one dose, making repeated vaccination and ...
[DOC File]Alan Hinman
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So let’s take a look at an animation about live vaccines. (Video 3 – “Live, Attenuated Vaccine” 25:35-28:31) The events that produce immunity with a live, attenuated vaccine are almost identical to those which lead to immunity following infection with the disease-causing form of the organism.
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Examples of non-compliance: ... Varicella, zoster (shingles), and live attenuated influenza vaccines must be stored in a freezer that has its own external door separate from the refrigerator. No matter how hard you try to adjust the. temperature to +5°F in a dorm-style refrigerator’s freezer, you.
[DOC File]Summary of information required for the biosecurity risk ...
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Examples of additional requirements include pathogen testing of vaccine intermediates/final product, increased documentation requirements or on-site audit requirements. ... or live attenuated vaccines already in use in Australia? Yes – Proceed to question 14. ... The department will conduct a process of public consultation for live vaccines ...
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