First line antihypertensive drugs

    • [PDF File]Choosing a first-line drug in the management of elevated ...

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      Articles 1816 www.thelancet.com Vol 394 November 16, 2019 Comprehensive comparative effectiveness and safety of first-line antihypertensive drug classes: a …

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    • Antihypertensive Medicine

      First-line drugs for hypertension. Cochrane Database of Systematic Reviews 2009, Issue 3. Art. No.:CD001841. DOI: 10.1002/14651858.CD001841.pub2. Research question - PICOS Q Based on RCTs do first-line antihypertensive drugs as compared to placebo or untreated ... First line treatment of primary hypertension • Therapy can be started from ...

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    • [PDF File]First-line medicines in the treatment of hypertension

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      Antihypertensive drugs as first-line therapy Version 1.0 15.07.2009 Institute for Quality and Efficiency in Health Care (IQWiG) - 2 - Data on an outcome were quantitatively synthesized in a meta-analysis, provided that the contents and methods of the study data made it feasible. A model with fixed effects was used for the primary analysis.

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    • [PDF File]First line treatment of primary hypertension

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      of first-line drugs. The World Health Organization program, the 'Guide to good prescribing', emphasises comparative safety, convenience and cost as well as efficacy as important discriminators in making choices.6 Comparative safety Compared with drugs used for other chronic disorders, antihypertensives are among the safest. They cause very little

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    • [PDF File]Hypertension Diagnosis and Treatment Guideline

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      to other second-line therapy drug regimens after their initially allocated treatments during the monotherapy and second-line therapy periods. Statistical analysis. The objective of these analyses was to com-pare SBP and DBP responses to both first-line (atenolol and amlodipine) and second-line drugs (bendroflumethiazide and

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    • [PDF File]Different antihypertensive drugs as first line therapy in ...

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      amines the evidence for thiazide diuretics as a class of first-line antihypertensive drugs in light of these treatment goals. The evidence indicates that low-dose thi-azides are preferable to high-dose thiazides and that low-dose thiazides are better than or equivalent to other antihypertensive drugs for each of the goals of therapy. T

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    • [PDF File]Comprehensive comparative effectiveness and safety of ...

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      single antihypertensive medicine is appropriate first-line treatment Selecting which antihypertensive to use can be based on co-morbidities and individual patient characteristics Thiazide diuretics, ACE inhibitors and calcium channel blockers are all appropriate initial …

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    • [PDF File]Which Antihypertensive? - bpac

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      first C Begin 2 drugs at same time, as separate pills or combination pill. Initial combination therapy is recommended if BP is greater than ... Pregnancy labetolol (first line), nifedipine, methyldopa Beta-1 Selective Beta-blockers – possibly safer in patients with COPD, asthma, diabetes, and …

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    • [PDF File]JNC 8 Hypertension Guideline Algorithm Initial Drugs of ...

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      Hypertension Diagnosis and Treatment Guideline ... are now listed as equivalent first-line choices for the general population. ACE inhibitor s and diuretics were first-line ... Alcohol, illicit drugs (e.g., cocaine and other stimulants), and smoking. Consider screening (see

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