Frank starling effect
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The Frank-Starling law of the heart equalizes the output of the right and left ventricles and keeps the same volume of blood flowing to both the systemic and pulmonary circulations. Myocardial contractility, the strength of contraction at any given preload, is affected by positive and negative inotropic agents.
[DOC File]Congestive Heart Failure - Josh Corwin
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Frank-Starling Law of the Heart. basically, two physiologists independently determined that strength of ventricular contraction varies directly with EDV (heart can contract at different strengths) ... Cardiac muscle length has a more pronounced effect on contraction strength than observed in skeletal muscle.
[DOC File]16 - Indiana State University
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The Frank Starling mechanism means. a. The greater the heart muscle is stretched during filling, the greater will be the force of contraction. b. Within reasonable limits – changes in the arterial pressure against which the heart pumps have almost no effect on the cardiac output.
Chapter 9 - Cardiac Physiology
Explain the Frank-Starling mechanism and its relationship to excitation-contraction coupling. Frank-Starling law: "energy of contraction is proportional to the initial length of the cardiac muscle fiber." For the heart, the length of the muscle fibers (ie, the extent of the preload) is proportionate to the end- …
[DOC File]Circulation MCQs
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Frank-Starling mechanism. Control of the heart by autonomic nerves; effect of ions. Excitatory and conductive system of the heart. Role of the different components of the conductive system. Velocity of conduction of the impulse. Control of heart rhythmicity and impulse conduction by the cardiac nerves.
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30. One way of stating the Frank-Starling law of the heart is that stroke volume is proportional to ___. A. the end-systolic volume. B. the end-diastolic volume. C. the afterload. D. the heart rate. E. contractility. 31. Baroreceptors are located in ___. A. the aorta and carotid sinuses. B. …
[DOC File]Division of physiology
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In a transplanted heart, increased SV secondary to the Frank Starling mechanism and increased HR and contractility secondary to noradrenaline effect appear sequentially. The postponed HR acceleration at the exercise onset contributes to delayed CO adaptation, …
Frank-Starling Law - an overview | ScienceDirect Topics
1. intrinsic: preloading (Frank-Starling effect) the heart intrinsically varies SV according to the EDV. within physiological limits, the more the myocardial muscle cells are stretched, the stronger the resulting contraction. the tension generated is proportional to the length of the muscle cell
[DOC File]EXERCISE AND HEART TRANSPLANTATION
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Compensatory neurochromal responses- triggered in response to reduction in CO (aka Frank-Starling mechanism- counter productive) Reduction in tissue perfusion- activation of SNS and renin-angiotensin-aldosterone system- vasoconstriction and increase Na and H2O retention. Increase plasma volume and venous pressure
[DOC File]Chapter 20
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Frank-Starling Principle: chronically increased EDV results in overstretching of muscle fibers; there is a loss of the optimal approximation of the actin and myosin filaments of myocyte sarcomeres. (contractility eventually decreases)
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