Fusion body myositis

• [PDF File]Chaperonemediated autophagy components are upregulated in …

  https://info.5y1.org/fusion-body-myositis_1_20cfec.html

  Chaperone-mediated autophagy components are upregulated in sporadic inclusion-body myositis muscle fibres M. Cacciottolo, A. Nogalska, C. D’Agostino, W. K. Engel and V. Askanas

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• [PDF File]Inclusion body myopathy associated with Paget disease of bone …

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  LETTERS Inclusion body myopathy associated with Paget disease of bone and frontotemporal dementia (IBMPFD) is a dominant progressive disorder that maps to chromosome 9p21.1–p12.

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• [PDF File]Mitochondrial profile and amyloidogenic molecules in sporadic …

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  myositis (NAM) and sporadic inclusion body myositis (sIBM). The common features are proximal muscle wasting and increasing difficulty with tasks requiring these muscles such as lifting objects or climbing steps among others. In addition, neck extensors and pharyngeal

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• Sporadic Inclusion Body Myositis: An Acquired Mitochondrial …

  Sporadic inclusion body myositis (IBM) is a rare condition, yet the most common inflammatory muscle disease in patients over 50 years old, with an annual incidence between 1 and 8 per million [1]. Most patients present initially with slowly progressive weakness of legs, arms, fingers and wrists.

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• [PDF File]Development of autoantibodies against muscle- specific FHL1 in …

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  myositis, which causes progressive muscle weakness. Several forms of the disease, including polymyositis (PM), dermatomyositis (DM), inclusion body myositis (IBM), and immune-mediated necrotizing myopathy can be distinguished on the basis of clinical features, muscle histopathology, and autoantibody profiles (1–4). For IBM,

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• Localization and Expression of Nuclear Factor of Activated T-Cells …

  (n = 10), inclusion body myositis (n = 11) and were compared to NFAT5 localization and expression in non-myopathic controls (n = 13). Muscle biopsies were studied by means of quantitative IHC and WB of total protein extracts. Results: In unaffected myoblasts, hyperosmolar stress ensues in NFAT5 nuclear

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• [PDF File]A Graph Theoretical Approach to Data Fusion

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  A Graph Theoretical Approach to Data Fusion Justina Zurauskienˇ e˙1+*, Paul DW Kirk2+, and Michael PH Stumpf1 1Theoretical Systems Biology group, Centre for Bioinformatics, Imperial College London, South Kensington Campus, SW7 2AZ, London, UK 2MRC Biostatistics Unit, Cambridge, CB2 0SR, Cambridge, UK *j.norkunaite@imperial.ac.uk +these authors contributed equally to this work ABSTRACT The rapid …

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• REVIEW Open Access Sporadic inclusion body myositis: the …

  REVIEW Open Access Sporadic inclusion body myositis: the genetic contributions to the pathogenesis Qiang Gang1,2*, Conceição Bettencourt1, Pedro Machado2, Michael G Hanna1,2 and Henry Houlden1,2 Abstract Sporadic inclusion body myositis (sIBM) is the commonest idiopathic inflammatory muscle disease in people over

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• [PDF File]Expression of myogenic regulatory factors and myo-endothelial ...

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  Expression of myogenic regulatory factors and myo-endothelial remodeling in sporadic inclusion body myositis Julia V. Wanschitza,d,⇑, Odile Dubourgf, Emmanuelle Lacened, Michael B. Fischerb, Romana Ho¨ftbergerc, Herbert Budkac, Norma B. Romerod, Bruno Eymardd,e, Serge Hersond,g, Gillian S. Butler-Browned, Thomas Voitd, Olivier Benvenisted,g aClinical Department of Neurology, Innsbruck Medical …

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• [PDF File]Mitochondrial Dysregulation in Skeletal Muscle from Patients …

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  the development of sporadic Inclusion Body Myositis (sIBM), however, mtDNA dyshomeostas along with structural and functional abnormalities have been observed in patients diagnosed with the disease [17]-[19]. Furthermore, Boncompagni, et al [20]. observed structural and functional alterations in mitochondria from

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