Glioblastoma progression what to expect
Investor Relations | Regeneron Pharmaceuticals Inc.
The median progression-free survival and overall survival were not reached at the data cutoff date with a median follow up of 6.9 months (range: 1.1 to 13.8 months; ongoing). One patient experienced progressive disease following an initial response to cemiplimab, and two patients were not evaluable for response due to death, which was ...
[DOCX File]Research | Minnesota State University, Mankato
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Glioblastoma tumor possesses a character of genetic heterogeneity, which underlies the inherent ability of a tumor to resist most treatment options. Additionally, glioblastoma is highly aggressive and the rapid tumor growth in the brain tissue makes the tumor cells refractory to surgery and radiation, leading to a frequent relapse.
[DOCX File]A RANDOMIZED PHASE III TRIAL OF MEMANTINE AND …
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Intracranial progression will be assessed at the time of the primary endpoint analysis, which is expected to occur once all patients have 6 months of follow-up. MRI scans at baseline and 6 months will be reviewed to determine intracranial progression centrally.
[DOC File]NCI Consent Form Template for Adult Cancer Trials
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If you had any additional surgeries for glioblastoma prior to enrolling on this study, this tissue will also be collected when tissue is available. If you need further surgery for your brain tumor while you are taking part in this study, pieces of cancer tissue from your tumor will …
[DOC File]I
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We used GSEA to compare the three mouse models: KrasLA, NNK-adenoma and NNK-carcinoma with a variety of human cancer subtypes: uterus, pancreas, breast, medulloblastoma, renal, prostate, bladder, ovary, glioblastoma, lung adenocarcinoma, lung carcinoid, lung squamous, and lung small-cell.
[DOCX File]Curcumin promotes differentiation of glioma‐initiating ...
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Furthermore, AKT protein levels reduction was confirmed. Our data, strongly suggest that curcuminexerts its cell-death properties by affecting the integrity of the reticulum, leading to paraptosis in the glioblastoma cells. These data unveils the versatility of curcumin to control cancer progression. Article Published . Date : Apr 29, 2018. 5.
First Keynote Lecture - ResearchGate
Taken together, our current results indicate that CIP2A is involved in human breast cancer progression and strongly suggest that CIP2A expression is linked to agressiveness of the mammary tumors.
[DOC File]PHS 2013-1 Solicitation for SBIR Contract Proposals
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Include the potential barriers to market entry and how you expect to overcome them. g. Senior/Key Personnel and Bibliography of Directly Related Work. ... analysis at the single cell level in order to understand the origin and role of these subpopulations of CTCs in cancer progression and treatment response. Enabling CTC analysis at the single ...
[DOCX File]AusPAR Attachment 2: Extract from the Clinical Evaluation ...
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Progression was also assessed with the MS functional composite (MSFC), which is a performance-based assessment of neurological disability in 3 domains: upper limb function is assessed with the 9-hole peg test, lower limb function with a 25-ft timed walk, and cognitive function with a paced auditory serial addition test (PASAT).
[DOC File]Research Area: This application addresses the broad ...
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TMEFF1 gene expression in glioblastoma varies by 4 orders of magnitude (row 1, column 1). The influence of TMEFF1 copy number on gene expression is modest (correlation=0.31, row 2, column 1 and row 1, column 2), while there is robust linear anti-correlation between TMEFF1 and hsa-mir-34a expression (correlation=0.53, row 4, column 1 and row 1 ...
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