Gr agonist
[DOCX File]GENERAL INTRODUCTION - OECD
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Drug treatments included clenbuterol hydrochloride, a long acting β 2 AR agonist (CLEN; 0.2 mg/mL saline/kg, i.p.) followed by a GR agonist, dexamethasone (DEX; 2 mg/mL corn oil/kg, s.c.). Since we were attempting to restore the activities of epinephrine and corticosterone at the basal levels that were completely depleted by AD procedure and ...
[DOCX File]University of Edinburgh
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D2 receptor agonist Hyperprolactinemia GI Upset, CNS, Insomnia Cheaper than Bromocriptine Chorionic Gonadotropin Natural Hormone Hypogonadotropic Hypogonadism Multiple Births. Ovarian Hyperstimulation Syndrome Mimics LH Gonadorelin Acetate ... Hypokalemia 10X higher affinity for MR than GR.
Topical 'dual-soft' glucocorticoid receptor agonist for ...
Male Sprague Dawley rats received bilateral infusions of vehicle or the glucocorticoid receptor (GR) agonist RU 28362 (3.0 or 10.0 ng) alone or together with either the (-adrenoceptor antagonist atenolol (1.25 (g), the (1-adrenoceptor antagonist urapidil (0.3 (g), or the cAMP/protein kinase A (PKA) inhibitor Rp-cAMPS (4.0 (g) into the mPFC 60 ...
[DOC File]Drug - University of Kentucky
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To examine the effect of AR signaling on metabolic glucocorticoid action, 8-week old male C57BL6/J mice (Jackson Laboratory) were exposed to the GR agonist corticosterone (CORT; Sigma-Aldrich) and AR agonist dihydrotestosterone (DHT; 5α-Androstan-17β-ol-3-one, Sigma-Aldrich) via subcutaneous implantation of slow-release pellets (100 mg).
[DOC File]Glucocorticoid-related molecular signaling pathways ...
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cortisol (11(-hydroxylase) Fludrocortisone Mineralocorticoid deficiency HTN, hypokalemia 10X affinity for MR than GR Spironolactone MR antagonist Mineralocorticoid excess Hyperkalemia, hyperchloremia High doses inhibit AR Calcium homeostasis Calcitriol 1,25-(OH)2-vit.D Vit.D-dependent rickets. Renal osteodystrophy. Psoriasis, leukemia
[DOCX File]U.S EPA Web Server
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Christoph Anacker, PhD1,2,3; Annamaria Cattaneo, PhD4; Alessia Luoni5; Ksenia Musaelyan, MD1; Patricia A. Zunszain, PhD1; Elena Milanesi4; Joanna Rybka, MSc6 ...
[DOC File]THE EFFECTS OF GLUCOCORTICOIDS ON (PREFRONTAL …
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For the antagonist testing, the 3 test methods have all classifications concordant while for the agonist testing, 4 classifications are not concordant with the 22Rv1/MMTV_GR-KO ARTA. A possible reason for this could be the different cell lines …
[DOC File]Organism - University of Kentucky
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Following incubation of endothelial cells for 4-hours in the absence or presence of desired agonist (100µM heme, or 10ng/ml TNF-α), cells were harvested using 5mM EDTA in calcium- and magnesium-free Hanks balanced salt solution.
[DOC File]Weebly
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: “Effects of lateral hypothalamic injections of glutamate receptor agonist (ATPA) and antagonist (D-AP5) on food intake in rats under simulated microgravity” Jenny McCallister: “Overeating induced by the glutamate receptor antagonist CNQX within the nucleus accumbens of satiated rats” Amelia Keaton
SUPPLEMENTARY MATERIALS, METHODS, and RESULTS
1994) administered the IV beta2-agonist as an infusion (range: 8.3 - 20 ug/min. to total doses of 500 ug - 3000 ug). Most studies (73%) used salbutamol as the. beta-agonist, except for 3 studies in which terbutaline was evaluated (Sharma 1. 1984; Van Renterghem 1987; Williams 1975), and 1 study where reproterol was used (Hussein 1986).
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