How do chemo drugs work
[DOC File]Pharmacology—Chemotherapy and Supportive Care
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The average growth fraction is 20%. Small, rapid growing (higher growth fraction) cancers respond better to chemo. Normal cells with high growth fractions are more susceptible to chemo drugs (GI mucosa, bone marrow). Log Kill Effect. Cancer growth is exponential. Chemo drugs are cytotoxic; they kill cells at various points of the cell cycle.
[DOCX File]Chemo/Haz Drugs SOP Template - University of Washington
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Purchase the smallest amount of [chemo/haz drug] feasible for specific tasks, or purchase [chemo/haz drug] diluted to the concentration for use. Provide hazardous chemical and specific SOP training to personnel working with [chemo/haz drug] and any other personnel authorized or required to be in the laboratory or shared space during work with ...
[DOCX File]TABLE OF CONTENTS
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UH Guideline for Chemotherapy and Other Hazardous Drugs Usage. INTRODUCTION
[DOC File]Clinical Applications of Antineoplastic Chemotherapy
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Understanding of mechanisms through which the drugs work. History . Paul Erlich coined the term chemotherapy . George Clowes at Roswell Park developed rodent lines to test potential drugs. Alkylating agents – First class. Product of a secret gas programme by USA. 1943 use in Hodgkin’s lymphoma.
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