How to treat vancomycin extravasation

    • [PDF File] VANCOMYCIN (FOR IV USE IN ADULTS)

      http://5y1.org/file/20478/vancomycin-for-iv-use-in-adults.pdf

      Vancomycin has a low pH and may cause venous irritation and tissue damage in cases of extravasation. If a central venous access device is unavailable, administer via a large peripheral vein monitoring insertion site closely using a recognised phlebitis scoring tool. Resite cannula at first signs of inflammation.

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    • [PDF File] Caring for a Suspected or Actual Extravasation

      http://5y1.org/file/20478/caring-for-a-suspected-or-actual-extravasation.pdf

      An extravasation is when a medication leaks from your vein into the tissue around it. This can cause skin irritation, blisters, and open wounds. It can happen anywhere an intravenous (IV) line is put into your skin.

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    • [PDF File] Microsoft Word - 311026-Non-Chemo extravasation

      http://5y1.org/file/20478/microsoft-word-311026-non-chemo-extravasation.pdf

      Some non-chemo drugs may be especially likely to harm soft tissue with infiltration or extravasation.21 They can be classified as follows:16,17,21,22,25 Hyperosmolar agents, which cause osmotic shifts leading to inflammation and cell death (e.g., hypertonic saline, parenteral nutrition, sodium bicarbonate).

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    • [PDF File] Vancomycin extravasation: Evaluation, treatment, and …

      http://5y1.org/file/20478/vancomycin-extravasation-evaluation-treatment-and.pdf

      Vancomycin extravasation was successfully managed by utilizing cold compress for the first 24 hours post-extravasation with common gauze open dressings and silver sulfadiazine 1% until the wound was healed. With a potential for vancomycin extravasation when administered peripherally, we would recommend central venous administration.

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    • [PDF File] Chemotherapy Extravasation Management - AAHA

      http://5y1.org/file/20478/chemotherapy-extravasation-management-aaha.pdf

      Extravasation is a term that describes a drug inadvertently or accidentally leaking into surrounding tissue or the subcutaneous space during IV infusions. The volume, contact time, and drug properties are all factors that have to be considered when assessing an extravasation event.

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    • [PDF File] Vancomycin extravasation: Evaluation, treatment, and …

      http://5y1.org/file/20478/vancomycin-extravasation-evaluation-treatment-and.pdf

      Vancomycin extravasation was successfully managed by utilizing cold compress for the first 24 hours post-extravasation with common gauze open dressings and silver sulfadiazine 1% until the wound was healed. With a potential for vancomycin extravasation when administered peripherally, we would recommend central venous administration.

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    • [PDF File] Guidelines for the Use of Vancomycin - UW Health

      http://5y1.org/file/20478/guidelines-for-the-use-of-vancomycin-uw-health.pdf

      The objective of this guideline is to improve the use of vancomycin by optimizing the evaluation of the clinical necessity for vancomycin therapy, dosing of vancomycin dosing based on pharmacodynamic and pharmacokinetic principles and parameters, and the monitoring of vancomycin, including therapeutic drug monitoring.

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    • [PDF File] Management Extravasation of a Systemic Anti-Cancer Therapy

      http://5y1.org/file/20478/management-extravasation-of-a-systemic-anti-cancer-therapy.pdf

      The purpose of this guideline is to provide clear guidance on the causes, prevention, recognition and management of an extravasation of a Systemic Anti-Cancer Therapy used in the treatment of malignant disease in the patient over the age of 16 who is being cared for in adult services. Extravasation is an oncology emergency and therefore it is …

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    • [PDF File] Management of Extravasation Injuries: A Focused Evaluation …

      http://5y1.org/file/20478/management-of-extravasation-injuries-a-focused-evaluation.pdf

      Prompt interdisciplinary action is often necessary for the treatment of extravasation injuries. Knowledge of the mechanism of extravasation-induced tissue injury, agents for reversal, and appropriate nonpharmacologic treatment methods is essential. The best therapeutic agent for treatment of vasopressor extravasation is intradermal phentolamine.

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    • [PDF File] Vesicant/Irritant Therapy Guide with Appropriate Vascular …

      http://5y1.org/file/20478/vesicant-irritant-therapy-guide-with-appropriate-vascular.pdf

      May be used where necessary for short term infusions depending on condition of patient, renal considerations, vascular status, awaiting CVAD insertion or culture results, length of treatement, or "line holiday" requirement. Easier to monitor extravasation to a PIV rather than a midline due to deeper vein in upper arms; makes it more difficult to dectect …

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    • [PDF File] Preventing IntraVenous Extravasation Injuries

      http://5y1.org/file/20478/preventing-intravenous-extravasation-injuries.pdf

      New Efforts: Immediate Feedback System. -Supports Reliable Hourly Checks (Volume) -Supports “R” Medication Injury Prevention (Toxicity) Automated (EPIC) Digital Messaging to VAT leadership and PIV team. Extravasations >30%. Extravasation Alert: X / Y Ratio 65% Room: B4103 Unit: B4N. Any Amount of “R” drugs.

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    • [PDF File] PRO: Extravasations and Flares with Vesicant and Irritant …

      http://5y1.org/file/20478/pro-extravasations-and-flares-with-vesicant-and-irritant.pdf

      1. Stop the administration of the drug at the first sign of flare and flush the IV line with a compatible flush solution. A flare reaction differs from extravasation. A flare reaction is characterized by streaking, erythema, pruritus, and/or hives along the affected vein without pain or loss of blood return.5,7.

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    • [PDF File] Peripheral venous extravasation injury

      http://5y1.org/file/20478/peripheral-venous-extravasation-injury.pdf

      Extravasation is the inadvertent administration or leakage of blood, lymph or other fluid (including medication) into the subcutaneous or subdermal tissues, instead of the intended vascular or lymphatic pathways.1,2 It remains a well-established risk of injection of peripheral. i. medications with reported rates between 0.1% and 6.5%.

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    • [PDF File] Appendix B: Vesicant/Irritant and Extravasation Management …

      http://5y1.org/file/20478/appendix-b-vesicant-irritant-and-extravasation-management.pdf

      Dosing Guidelines for Drugs Used to Manage Extravasations: Dexrazoxane: 1000mg/m2 (maximum dose= 2000mg/day) by intravenous infusion on days 1 and 2, followed by 500mg/m2 (maximum dose = 1000mg/day) by intravenous infusion on day 3. Do not administer into same limb or site at which extravasation occurred.

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    • [PDF File] Vesicant Extravasation Part II: Evidence-Based Management …

      http://5y1.org/file/20478/vesicant-extravasation-part-ii-evidence-based-management.pdf

      ions and differentiation of vesicant extravasation from other local IV site reactions. When evidence is weak or mis. ing, logical application of data-based or empirical management strategies is critical. Actions may include timely administration of subcutaneous or topical antidotes, comfort measures, and surgical interven.

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    • [PDF File] APPENDIX E: Medications Used to Treat or Minimize Injury …

      http://5y1.org/file/20478/appendix-e-medications-used-to-treat-or-minimize-injury.pdf

      The use of phentolamine in the prevention of dopamine-induced tissue extravasa-tion. J Crit Care. 1998;13:13-20; Camp-Sorrell D. Developing extravasation protocols and monitoring outcomes. J Intraven Nurs. 1998;21:232-239; Zenk KE, Dungy CI, Greene GR. Nafcillin extravasation injury: use of hyaluronidase as an antidote.

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    • [PDF File] Extravasation1 Management (Vesicant and Contrast Agents)

      http://5y1.org/file/20478/extravasation1-management-vesicant-and-contrast-agents.pdf

      Signs and symptoms of extravasation include but are not limited to the following: Immediate extravasation: Refers to those reactions typically occurring during or shortly after vesicant administration. Pain, redness, or swelling on or around the injection/infusion site. Resistance when performing IVP.

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    • [PDF File] Extravasation Policy

      http://5y1.org/file/20478/extravasation-policy.pdf

      This policy is the Trust approved document for managing the risks from extravasation which are associated with the administration of certain intravenous treatments including chemotherapy. It sets down general principles for dealing with an extravasation as well as drug-specific measures.

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    • [PDF File] Guidelines for the Management of Extravasation G

      http://5y1.org/file/20478/guidelines-for-the-management-of-extravasation-g.pdf

      L. The disperse and dilute strategy involves the initiation of appropriate measures for the extravasation of vinca alkaloids and non DNA binding agents, e.g taxanes the use of warm compresses to prompt vasodilatation and encourage blood flow in the tissues which helps to spread the extravasation.

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    • [PDF File] Vancomycin | Memorial Sloan Kettering Cancer Center

      http://5y1.org/file/20478/vancomycin-memorial-sloan-kettering-cancer-center.pdf

      Vancomycin This information from Lexicomp explains what you need to know about this medication, including what it’s used for, how to take it, its side effects, and when to call your healthcare provider.

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    • [PDF File] MANAGEMENT OF EXTRAVASATION: TREATMENT SUMMARY

      http://5y1.org/file/20478/management-of-extravasation-treatment-summary.pdf

      Extravasation suspected – resistance or absence of free flow, swelling, discomfort, burning, pain. STOP the injection immediately, but leave the cannula in place.

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    • [PDF File] Monographs for Commonly Administered Intravenous …

      http://5y1.org/file/20478/monographs-for-commonly-administered-intravenous.pdf

      Monographs for Commonly Administered Intravenous Medications in Home and Community Care Vancomycin. Drug Class1. Antibiotic – glycopeptide. Spectrum1. Refer to product monograph for complete spectrum. Gram positive pathogens (e.g., S. aureus, Enterococcus, S. viridans, methicillin-resistant staph aureus (MRSA) Cross Sensitivities / Allergies1.

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    • [PDF File] What is the optimal approach to infiltration and extravasation …

      http://5y1.org/file/20478/what-is-the-optimal-approach-to-infiltration-and-extravasation.pdf

      Q: What is the optimal approach to infi ltration and extravasation of nonchemotherapy medications? A: The immediate response to leakage of intra-venous (IV) medications is warm or cold compression and assessment of severity. If the severity is grade 3 or above,1 an antidote is needed and must be identifi ed quickly.

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    • [PDF File] GUIDE TO EXTRAVASATION MANAGEMENT IN ADULT

      http://5y1.org/file/20478/guide-to-extravasation-management-in-adult.pdf

      Large, well-designed, controlled clinical trials in humans are not available to support the development of extravasation management guidelines. Available data generally consists of case reports, trials utilizing animal models, and small studies with evidence of poor or inconsistent quality. This lack of evidence creates challenges in validating specific …

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    • [PDF File] Management of Extravasation Injuries: A Focused Evaluation …

      http://5y1.org/file/20478/management-of-extravasation-injuries-a-focused-evaluation.pdf

      Prompt interdisciplinary action is often necessary for the treatment of extravasation injuries. Knowledge of the mechanism of extravasation-induced tissue injury, agents for reversal, and appropriate nonpharmacologic treatment methods is essential. The best therapeutic agent for treatment of vasopressor extravasation is intradermal phentolamine.

      TAG:


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