Increased bilirubin in newborn
[DOC File]GI—Introduction to GI and Bilirubin
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Unconjugated hyperbilirubinemia (physiologic jaundice) – common in first week of life, due to increased bilirubin load as well as decreased hepatic cell uptake of bilirubin and deficient hepatic conjugation. Pre-term infants are more susceptible to kernicterus (neurologic damage) due to less effective blood-brain barrier.
[DOC File]Physiologic differences between infants, children and adults
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Newborn Babies have more red blood cells than they need after birth and these excess red blood cells are gradually broken down in the first few days of the baby’s life .One of the end products from this process is bilirubin. Bilirubin is normally processed in the liver and is removed from the body in the urine and bowel motions.
[DOCX File]Word: Hyperbilirubinemia Management For Preterm Infants
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In the newborn patient with hemolytic jaundice and neonatal jaundice, the increase in the total bilirubin is primarily due to the indirect bilirubin fraction. Causes of this jaundice condition include Rh, ABO, or other blood group incompatibilities, by hepatic immaturity, or by hereditary defects in bilirubin conjugation.1
[DOCX File]Baby- Jaundice and phototherapy
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- a single bilirubin measurement in the Low Intermediate Risk Zone in infants who have any of the risk factors listed in section C above. Table 2. Bilirubin Risk Determination for Well Newborns at 36 or more weeks’ gestational age with birth weight 2,000 gm or more or 35 or more weeks’ gestational age and birth weight of 2,500 gm or more*
[DOC File]A STUDY TO ASSESS THE FACTORS AFFECTING NEONATAL …
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Normal bilirubin in the newborn is 1-12mg/dL. Neonatal and breast feeding jaundice is mild, unconjugated hyperbilirubinemia between days 2-5 after birth with peak levels at 5-10mg/dL. They decline to normal concentrations within 2 weeks.
Newborn jaundice: MedlinePlus Medical Encyclopedia
The entry of bilirubin into the brain is more likely through a leaky BBB secondary to conditions such as acidosis, asphyxia, inflammation, meningitis or an abrupt increase in cerebral blood flow (including hypercarbia and seizures) ( Volpe’s Neurology of the Newborn).
[DOC File]Prepared By - Beckman Coulter
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Neonatal jaundice is the term used when a newborn has an excessive Amount of bilirubin in the blood. Bilirubin is a yellowish red pigment that Is formed and released into the blood stream when red blood cells are broken down.
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