Inducible ischemia definition

    • [DOCX File]XV - Harvard University

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      Inducible Pluripotent Stem Cells and Kidney Regeneration. 1RC1 DK0864406-01. PI ($313,966) ... Mechanisms of kidney mitochondrial injury with ischemia. Symposium on Clinical Ischemic Syndromes, U. of Michigan. 1988. Calcium and phospholipase activation in the mesangial cell.

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    • [DOCX File]Imperial College London

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      in patients with stable CAD. However, at variance with hs-cTnT, only the presence of inducible myocardial ischemia was an independent predictor of higher NT-proBNP. Patients with obstructive coronary lesions and inducible ischemia had significantly higher values of NT-proBNP than all the other patients (Figure 2).

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    • ARTHUR J

      A Single Blind, Randomized, Placebo-Controlled Phase II Multi-Center Trial to Evaluate the Ability of DMP 115 Dobutamine Stress Echocardiography to Detect Inducible Ischemic Heart Disease in Subjects with Suspected Coronary Artery Disease. DuPont Pharmaceuticals, November 1999 - 2000.

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    • [DOC File]UKZN Innerweb - Home

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      Β-blockers for inducible ischemia . Hypertension should be controlled preferably with ACE inhibitor . OPERATIVE MANAGEMENT10,11,12. The relative indication for OPEN repair versus Endovascular repair (EVAR) is in a constant state of evolution, and currently the choice is left to the surgeon.

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    • [DOC File]Microsoft

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      In certain instances, troponin elevation due to ischemic demand may unmask severe coronary artery disease (CAD) by increasing myocardial oxygen demand in the presence of fixed coronary stenosis. Consequently once the patient recovers from the acute illness, a stress test for inducible ischemia or coronary angiography can be helpful.

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    • [DOC File]ICH-Protocol Template - Emmes

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      May 12, 2008 · This definition is not intended to include experiences of relatively minor medical significance such as uncomplicated headache, nausea, vomiting, diarrhea, influenza, accidental trauma (i.e., sprained ankle) that may interfere or prevent everyday life functions but do not constitute a substantial disruption.

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    • Online References:

      Inducible myocardial ischemia demonstrated by: An early positive stress test defined as ST elevation or ≥ 2 mm ST-depression prior to 5 METs. Reversible wall motion abnormality on stress echocardiography.

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    • [DOCX File]5. Study Population - TransCelerate

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      The definition of “MACE” can vary from study to study, both in the events included and in the definition of those events. ... Definite evidence of inducible myocardial ischemia as demonstrated by: • an early positive exercise stress test, defined as ST elevation or ≥ 2 mm ST depression prior to 5 mets . OR

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    • [DOC File]PubMed - Stanford University

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      Background- Under normoxic conditions, hypoxia-inducible factor (HIF)-1α is rapidly degraded by 2 hydroxylases: prolyl hydroxylase (PHD) and factor-inhibiting HIF-1 (FIH). Because HIF-1α mediates the cardioprotective response to ischemic injury, its upregulation may be an effective therapeutic option for ischemic heart failure.

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    • ir.akebia.com

      UNITED STATES. SECURITIES AND EXCHANGE COMMISSION. Washington, D.C. 20549. FORM 10-K (Mark One) ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 193

      inducible ischemia meaning


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