Induction dose of propofol

    • [DOC File]RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES …

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      reduction in propofol dose requirements for induction than the propofol group. 4.Tzabar et al., in 1996, studied 80 patients who received an i.v. bolus of. midazolam (either 0, 1, 2 or 4mg) 4min before a propofol infusion. Anaesthesia was successfully induced in 3mins in 45% of patients receiving no

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    • [DOC File]Basic Pharmacology - Angelfire

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      Factors determining the effect of propofol What is the induction dose of propofol and what is its disposition in elderly patients? Propofol uptake and distribution Draw a concentration/time curve after an IV bolus of propofol Pharmacokinetics of propofol infusions Calculation of propofol dosage for TIVA Draw the plasma concentration time curve ...

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    • [DOC File]SMALL ANIMAL ANESTHESIA GUIDE - VASG

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      Dose lidocaine @ 1 ml per 12-14 lb. Induction. Propofol. 0.5 to 3.0 mg/lb IV over 30 to 90 seconds followed by lidocaine 1 mg/lb IV, if needed, to deepen anesthetic plane and facilitate intubation . Maintenance. Isoflurane/Sevoflurane Remember MAC decreases significantly during pregnancy. Support. IV fluid support is a basic requirement ...

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    • [DOC File]National PBM Monograph Template Rev20091005

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      At sub-anesthesia induction doses (25-75 mcg/kg/min), propofol produces sedation and amnesia. Intravenous injection of propofol has an onset of action of about 30-45 seconds …

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    • [DOC File]Propofol Dosing Guidelines

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      Propofol Dosing Caveats. I. Induction: A. Even small boluses (1 2 cc) may cause apnea, especially following a premed. B. Reduce propofol doses by 40 60% for elderly patients, sick patients, or following a heavy premed. II. Maintenance: A. Check repeatedly that the infusion is running. Continuous infusions are prone to equipment problems, such ...

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    • [DOCX File]University of Edinburgh

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      Predosing with propofol has been reported in human anaesthesia. The technique is described as the administration of a fixed dose of propofol 2 minutes before induction of anaesthesia with propofol (Anderson & Robb 1998; Djaiani & Ribes-Pastor 1999).

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    • [DOC File]ICU SEDATION GUIDELINES

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      Their protocol consisted of an induction dose of ketamine 2mg/kg IV followed by ketamine 4mg/kg IM. Subsequent IM doses of ketamine were administered when the patient made purposeful movements or nystagmus reappeared. A final dose of ketamine 1mg/kg was …

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    • [DOCX File]WordPress.com

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      Sedation Drugs; Propofol. MOA: potentiates GABA; anti-emetic; amnesia; no analgesia; decr ICP (but cerebral protective effects offset by hypotension); anti-convulsant. Onset: 9-20 seconds. Offset: 3-9 mins; rapid redistribution. Dose: Induction: 1-2mg/kg. Procedural sedation: 0.5 – 1mg/kg over 1-5mins 0.5mg/kg boluses (initial dose 2mg/kg in children;

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    • [DOC File]Stanford University

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      The induction dose of propofol ranges from 1-2.5 mg/kg, administered as several divided doses (2-3 cc per dose). Elderly patients and patients receiving opioids prior to induction should receive doses closer to 1 mg/kg.

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    • [DOC File]1

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      Propofol is a preferred inducing agent for short surgical procedures is a nonopioid, nonbarbiturate, sedative‑hypnotic agent with rapid induction and recovery times and antiemetic effects 3. However, adverse effects include dose‑dependent cardiorespiratory depression, injection pain, and having no analgesic properties 3, 4,5.

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