Induction dose of propofol
[DOC File]RAJIV GANDHI UNIVERSITY OF HEALTH SCIENCES …
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reduction in propofol dose requirements for induction than the propofol group. 4.Tzabar et al., in 1996, studied 80 patients who received an i.v. bolus of. midazolam (either 0, 1, 2 or 4mg) 4min before a propofol infusion. Anaesthesia was successfully induced in 3mins in 45% of patients receiving no
[DOC File]Basic Pharmacology - Angelfire
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Factors determining the effect of propofol What is the induction dose of propofol and what is its disposition in elderly patients? Propofol uptake and distribution Draw a concentration/time curve after an IV bolus of propofol Pharmacokinetics of propofol infusions Calculation of propofol dosage for TIVA Draw the plasma concentration time curve ...
[DOC File]SMALL ANIMAL ANESTHESIA GUIDE - VASG
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Dose lidocaine @ 1 ml per 12-14 lb. Induction. Propofol. 0.5 to 3.0 mg/lb IV over 30 to 90 seconds followed by lidocaine 1 mg/lb IV, if needed, to deepen anesthetic plane and facilitate intubation . Maintenance. Isoflurane/Sevoflurane Remember MAC decreases significantly during pregnancy. Support. IV fluid support is a basic requirement ...
[DOC File]National PBM Monograph Template Rev20091005
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At sub-anesthesia induction doses (25-75 mcg/kg/min), propofol produces sedation and amnesia. Intravenous injection of propofol has an onset of action of about 30-45 seconds …
[DOC File]Propofol Dosing Guidelines
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Propofol Dosing Caveats. I. Induction: A. Even small boluses (1 2 cc) may cause apnea, especially following a premed. B. Reduce propofol doses by 40 60% for elderly patients, sick patients, or following a heavy premed. II. Maintenance: A. Check repeatedly that the infusion is running. Continuous infusions are prone to equipment problems, such ...
[DOCX File]University of Edinburgh
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Predosing with propofol has been reported in human anaesthesia. The technique is described as the administration of a fixed dose of propofol 2 minutes before induction of anaesthesia with propofol (Anderson & Robb 1998; Djaiani & Ribes-Pastor 1999).
[DOC File]ICU SEDATION GUIDELINES
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Their protocol consisted of an induction dose of ketamine 2mg/kg IV followed by ketamine 4mg/kg IM. Subsequent IM doses of ketamine were administered when the patient made purposeful movements or nystagmus reappeared. A final dose of ketamine 1mg/kg was …
[DOCX File]WordPress.com
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Sedation Drugs; Propofol. MOA: potentiates GABA; anti-emetic; amnesia; no analgesia; decr ICP (but cerebral protective effects offset by hypotension); anti-convulsant. Onset: 9-20 seconds. Offset: 3-9 mins; rapid redistribution. Dose: Induction: 1-2mg/kg. Procedural sedation: 0.5 – 1mg/kg over 1-5mins 0.5mg/kg boluses (initial dose 2mg/kg in children;
[DOC File]Stanford University
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The induction dose of propofol ranges from 1-2.5 mg/kg, administered as several divided doses (2-3 cc per dose). Elderly patients and patients receiving opioids prior to induction should receive doses closer to 1 mg/kg.
[DOC File]1
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Propofol is a preferred inducing agent for short surgical procedures is a nonopioid, nonbarbiturate, sedative‑hypnotic agent with rapid induction and recovery times and antiemetic effects 3. However, adverse effects include dose‑dependent cardiorespiratory depression, injection pain, and having no analgesic properties 3, 4,5.
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