Insulin and cholesterol synthesis
[DOC File]Lipid Metabolism
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During fasting cholesterol synthesis is low. HMG-CoA reductase is the key enzyme for cholesterol synthesis. It is present in two forms active (dephosphorylated) and inactive (phosphorylated). The activity of the enzyme is regulated by cAMP dependent enzyme system, increased by carbohydrate feeding and by insulin and decreased by fasting and ...
[DOC File]Chapter 16 Section A: Control and Integration of ...
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Cholesterol isn’t a source of energy. What are its roles in human physiology? ... How does insulin lead to protein synthesis in muscle cells? Create a negative feedback loop for plasma glucose homeostasis beginning with the stimulus: eating a large Snickers candy bar. Be sure to include the sensors (receptors), afferent pathway (if there is ...
INSULIN, GLUCAGON, AND DIABETES MELLITUS
G. Insulin promotes protein formation and prevents the degradation of proteins. H. Lack of insulin leads to catabolism of protein, cessation of protein synthesis, plasma AA increase . I. Insulin in combination with growth hormone stimulates growth. VI. Control of Insulin Secretion. A. …
[DOC File]1
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Statins: inhibit HMG-CoA-Reductase, the rate limiting enzyme in the cholesterol synthesis pathway => increased uptake of LDL from plasma Fibrates: PPAR agonists that trigger upregulation of fatty acid metabolizing enzymes and stimulate lipoprotein-lipase activity.
[DOC File]Introduction to the Endocrine System
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Stimulate synthesis of enzymes or structural proteins. ... Stores lipids, especially cholesterol and fatty acids. Manufactures steroid hormones: adrenocortical steroids (corticosteroids) ... Beta cells secrete insulin, stimulating transport of glucose across plasma membranes.
[DOC File]Introduction to Cholesterol Metabolism
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Cholesterol synthesis in microsomal (endoplasmic reticulum) and cytosol fraction of the cell is responsible for cholesterol synthesis from the two-carbon acetate group of acetyl-CoA. A little more than half the cholesterol of the body arises by synthesis (about 700 mg/dL), and the remainder is provided by the average diet.
[DOC File]Diabetes, Insulin Resistance and Cardiovascular Disease 8 ...
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The researchers also found that cholesterol synthesis was reduced with increased meal frequency. They also observed lower GIP (a hormone that stimulates insulin release) levels and lower insulin levels throughout the day in subjects consuming 6 vs 3 meals daily.
[DOC File]Lipid and Insulin Resistance
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Lipid and Insulin Resistance. 5. ... due to complications, clearly correlated with efficaciousness of tissue repair, bone synthesis, tissue heal, a.s.o., all events genetically directed. ... among children of dyslipidemic parents only some present high cholesterol blood concentration (total Ch. …
Endo 1 - Ohio University
The largest genetic risk of T1 diabetes involves certain polymorphisms of Major Histocompatibility Complex (MHC) genes on Chromosome 6; more than 90% of those with T1 diabetes have one or both of the following two human leukocyte antigen (HLA) alleles: HLA-DR3,DQB1*0201 and HLA-DR4,DQB1*0302; in fact, these alleles account for about 50% of the genetic risk of T1 diabetes; non-HLA polymorphisms ...
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