Iv fentanyl to morphine equivalent

    • [PDF File] Opioid PCA Conversion to Oral Opioid Regimen

      http://5y1.org/file/22117/opioid-pca-conversion-to-oral-opioid-regimen.pdf

      Morphine sulfate 20- 35 mg Q4H PRN ... * Estimated MEDD for hydromorphone IV and fentanyl IV ** Includes 20-50% reduction for incomplete cross-tolerance *** May consider plain oxycodone (Roxicodone®) if …

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    • [PDF File] Transdermal and Parenteral Fentanyl Dosage Calculations …

      http://5y1.org/file/22117/transdermal-and-parenteral-fentanyl-dosage-calculations.pdf

      With this delivery system high voltage electric pulses of extremely short duration enhance skin permeability and consequently, fentanyl absorption. In this chapter we will focus on conversion calculations involving switching to and from transdermal fentanyl, and conversion calculations involving IV fentanyl.

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    • [PDF File] Opioid Dose Equivalence Calculation Table - ANZCA

      http://5y1.org/file/22117/opioid-dose-equivalence-calculation-table-anzca.pdf

      This opioid dose equivalence table is intended for comparison of different opioid and opioid formulations in individual patients or in patient cohorts. Caution is required if opioid dose equivalence tables are used to guide opioid switching, as the administration of a calculated ‘equivalent’ dose of the replacement opioid may lead to ...

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    • [PDF File] Slide 1

      http://5y1.org/file/22117/slide-1.pdf

      Slide 1. Table 1: Equianalgesic opioid conversions: Amount of drug administered to patient multiplied by the conversion factor equals the equianalgesic morphine equivalency. (American Pain Society, 2003 & 2008) Drug. Equivalency to 1 mg IV morphine.

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    • [PDF File] Newborn Critical Care Center (NCCC) Clinical Guidelines

      http://5y1.org/file/22117/newborn-critical-care-center-nccc-clinical-guidelines.pdf

      Patients develop tolerance to fentanyl faster than morphine. Continuous or scheduled dosing of fentanyl for 5 days or more necessitates weaning rather than abrupt discontinuation. Higher doses over shorter duration can also potentiate withdrawal.

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    • [PDF File] Opioid Equianalgesic Table - University of Toronto

      http://5y1.org/file/22117/opioid-equianalgesic-table-university-of-toronto.pdf

      Equianalgesic doses have been derived based on studies using typical opioid doses, for acute, short-term use. With chronic use, tolerance develops, resulting in reduced efficacy and increased dosing requirement. Due to lack of complete cross tolerance among opioids, when switching from one opioid to another, it is often necessary to use a lower than …

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    • [PDF File] Opioid Conversion Tables - ASHP

      http://5y1.org/file/22117/opioid-conversion-tables-ashp.pdf

      Opioid Conversion Tables. Ernest Dole, Pharm.D., BCPS, PhC, FASHP Clinical Pharmacist, University of New Mexico Hospitals Chronic Pain Consultation & Treatment Center. Table 1: Pharmacokinetic Data for Oral Opioids. Starting Dose.

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    • [PDF File] Opioid Conversion Guidance - Better Safer Care

      http://5y1.org/file/22117/opioid-conversion-guidance-better-safer-care.pdf

      Transmucosal fentanyl products are available for breakthrough cancer pain that is not adequately managed by other short-acting opioids. They can be considered in patients who are opioid tolerant, i.e. are already taking the equivalent or higher dose of oral morphine 60 mg daily or an equianalgesic dose of another opioid for at least a week.

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    • [PDF File] Opioid Dose Equivalence Calculation Table

      http://5y1.org/file/22117/opioid-dose-equivalence-calculation-table.pdf

      This opioid dose equivalence table is intended for comparison of different opioid and opioid formulations in individual patients or in patient cohorts. Caution is required if opioid dose equivalence tables are used to guide opioid switching, as the administration of a calculated ‘equivalent’ dose of the replacement opioid may lead to ...

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    • [PDF File] FEFF004C00610079006F0075007400200031 - BC Renal

      http://5y1.org/file/22117/feff004c00610079006f0075007400200031-bc-renal.pdf

      Fentanyl transdermal patch is not recommended in opioid-naïve patients. Previous opioid should be tapered over first 12 hours of fentanyl as absorption is delayed. Recommended conversion from oral daily hydromorphone equivalent to fentanyl is as follows:

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    • [PDF File] Opioid Analgesics - Home | Stanford Medicine

      http://5y1.org/file/22117/opioid-analgesics-home-stanford-medicine.pdf

      Hydrophilic, semi-synthetic (from morphine), hydrogenated ketone Potency approximately 5x greater than that of morphine Low oral bioavailability Converting from IV to PO, dosage increased by approximately 4x Peak effect at 15-30 minutes when given intravenous; duration 2-3 hours Hepatic metabolism by phase 2 glucuronidation Hydromorphone-3 ...

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    • [PDF File] Appendix A: Equianalgesic Conversion for Morphine - Gov

      http://5y1.org/file/22117/appendix-a-equianalgesic-conversion-for-morphine-gov.pdf

      Initiation of fentanyl in patients who are opioid-naïve is contraindicated at any dose. The conversion table is unidirectional only and should ONLY be used to convert adult patients from their current oral or parenteral opioid analgesic to the approximate fentanyl transdermal patch for use in chronic pain.

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    • [PDF File] Fentanyl Citrate Injection, USP - Food and Drug …

      http://5y1.org/file/22117/fentanyl-citrate-injection-usp-food-and-drug.pdf

      Fentanyl Citrate Injection, USP is a sterile, non-pyrogenic, preservative free aqueous solution for intravenous or intramuscular injection. CLINICAL PHARMACOLOGY Fentanyl citrate is a potent opioid agonist. A dose of 100 mcg (0.1 mg) (2.0 mL) is approximately equivalent in analgesic activity to 10 mg of morphine or 75 mg of meperidine.

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    • [PDF File] Opioid Conversion Tables - ASHP

      http://5y1.org/file/22117/opioid-conversion-tables-ashp.pdf

      Opioid Conversion Tables. Ernest Dole, Pharm.D., BCPS, PhC, FASHP Clinical Pharmacist, University of New Mexico Hospitals Chronic Pain Consultation & Treatment Center. Table 1: Pharmacokinetic Data for Oral Opioids. Starting Dose.

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    • [PDF File] dih33_group 1..500 - Lexicomp

      http://5y1.org/file/22117/dih33-group-1-500-lexicomp.pdf

      Opioid Conversion Table This table serves as a general guide to opioid conversion. Utilization of a direct conversion without a detailed patient and medication assessment is not recommended and may result in over- or underdosing. Consider reducing the predicted equianalgesic dose by 25% to 50% to limit significant incomplete cross-tolerance …

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    • [PDF File] Opioid dose conversion guide

      http://5y1.org/file/22117/opioid-dose-conversion-guide.pdf

      opioid conversion. 14.1 FINAL. Opioid dose conversion guide. Adapted from BNF 2020 The conversations are approximations and need to be adjusted to the individual patient. Oral morphine. Subcutaneous morphine. Oral oxycodone. Subcutaneous oxycodone/diamorphine*. Subcutaneous alfentanil.

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    • [PDF File] Causes of death definitions

      http://5y1.org/file/22117/causes-of-death-definitions.pdf

      Comparing opioids: A guide to estimating oral morphine equivalents (OME) in research. Technical Report No. 329 Sydney: National Drug and Alcohol Research Centre, University of NSW.

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    • [PDF File] Conversion of Opioid Medicines Dosages

      http://5y1.org/file/22117/conversion-of-opioid-medicines-dosages.pdf

      699FM.3 CONVERSION OF OPIOID MEDICINES DOSAGES This guideline details equivalent dosages between opioids. There are 2 tables below: Opioid Conversion Chart: This provides advice on equivalent doses between opioid preparation for use by non-specialist clinical teams.

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    • [PDF File] Morphine - SA Health

      http://5y1.org/file/22117/morphine-sa-health.pdf

      Conversion of Intravenous to Oral Morphine, and Intravenous fentanyl to Intravenous or Oral morphine The below conversions between opiates and formulations should only serve as a general guide. Multiple factors like inter- and intra-individual difference in opioid pharmacology may influence the accuracy of dose calculations.

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    • [PDF File] PRINCIPLES OF ANTINEOPLASTIC THERAPY

      http://5y1.org/file/22117/principles-of-antineoplastic-therapy.pdf

      The analgesic activity ratio of 10 mg IM morphine to 100 micrograms of IV fentanyl was used to derive the equivalence of morphine to fentanyl patches. A 10 mg IM or 60 mg PO dose of morphine every 4 hours for 24 hours (total 60 mg/day IM or 360 mg/day oral) was considered approximately equivalent to a fentanyl 100 microgram patch.

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    • [PDF File] PDMP Morphine Milligram Equivalents Fact Sheet

      http://5y1.org/file/22117/pdmp-morphine-milligram-equivalents-fact-sheet.pdf

      PDMPMorphine Milligram Equivalents Fact Sheet Morphine milligram equivalents (MME) or morphine equivalent doses (MED) are values that represent the potency of an opioid dose relative to morphine. MME is intended to help clinicians make safe, appropriate decisions concerning changes to opioid regimens. Using a standard conversion factor developed …

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    • [PDF File] Equianalgesic Chart (Changes in italics) - UI Health Care

      http://5y1.org/file/22117/equianalgesic-chart-changes-in-italics-ui-health-care.pdf

      The next step is to convert 25 mg of oral hydromorphone to the daily oral morphine equivalent dose (DOMED). The equianalgesic chart indicates that 7.5 mg of oral hydromorphone is equal to 30 mg of oral morphine. The patient’s calculated dose of 25 mg of oral hydromorphone is equal to 100 mg of oral morphine.

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